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compositionComposition:DUTASTERIDE-0.5MG+SILODOSIN-8MG
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Prescription Medicine
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Siloflow 8 D Tablet is used to treat the symptoms of benign prostatic hyperplasia (BPH) in adults with an enlarged prostate gland. It helps to relieve symptoms such as difficulty urinating or urge to urinate more often and improve your ability to urinate. It contains Silodosin and Dutasteride, which relaxes smooth muscles in the bladder and prostate and shrink of the size of the prostate gland. It reduces the BPH symptoms and improves your ability to urinate. In some cases, you may experience certain common side effects such as dizziness, headache, nasal congestion (stuffy nose), and diarrhoea. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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More about the Product

Composition :

DUTASTERIDE-0.5MG+SILODOSIN-8MG

Manufacturer/Marketer :

Nephurocare Pharma Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Siloflow 8 D Tablet

Siloflow 8 D Tablet is a combination prescription medication used to treat the symptoms of an enlarged prostate, a condition medically known as benign prostatic hyperplasia (BPH). It helps relieve uncomfortable urinary symptoms such as a weak stream, straining, and the frequent or urgent need to urinate. This treatment is specifically formulated for men experiencing prostate gland enlargement.

To achieve the best results, you must take this medicine consistently every day as prescribed by your doctor. It should be taken with a meal, preferably at the same time each day, to help your body absorb the medicine properly. Incorporating lifestyle changes, such as limiting your fluid intake before bed and reducing caffeine, can further support the effectiveness of this treatment.

While taking Siloflow 8 D Tablet , you may experience mild side effects, such as a runny nose or changes in ejaculation. However, you must contact your doctor right away if you experience serious symptoms, such as severe dizziness, fainting, or signs of a severe allergic reaction. Your pharmacist or doctor can guide you on what to expect during your treatment.

Do not take this if you are a woman, a child, or if you have severe kidney or liver damage. It is also important to avoid this medication if you have a known allergy to any of its ingredients. Always talk to your doctor or pharmacist to ensure this medicine is safe for your specific health conditions before starting.

This medication can interact with other drugs, especially blood pressure medicines, which may increase the risk of dizziness. Pregnant women, or those who may become pregnant, must never handle these tablets because the active ingredients can be absorbed through the skin and cause harm to a male fetus. Elderly patients should also take extra care, as they may be more prone to dizziness and falls while taking this medication
 

Uses of Siloflow 8 D Tablet

Siloflow 8 D Tablet may be prescribed for the following condition: 

  • Benign Prostatic Hyperplasia (BPH): Siloflow 8 D Tablet helps shrink the enlarged prostate gland and relaxes the muscles in the bladder neck and prostate, making it easier to urinate and relieving painful or frequent urinary symptoms.
     

Key Benefits

Siloflow 8 D Tablet helps relieve urinary symptoms caused by an enlarged prostate (benign prostatic hyperplasia). This combination works to improve urine flow while also addressing the underlying enlargement of the prostate.

  • Improves Urine Flow: Helps relax the muscles around the prostate and bladder, making urination easier and improving urinary stream strength.
  • Reduces Urinary Symptoms: Helps relieve symptoms such as difficulty starting urination, weak urine flow, frequent urination, and the feeling of incomplete bladder emptying.
  • Decreases Night-Time Urination: May reduce the need to wake up frequently at night to pass urine, supporting better sleep quality.
  • Helps Shrink the Prostate: DUTASTERIDE gradually reduces prostate size, helping address the underlying cause of symptoms.
  • Reduces the Risk of Complications: Long-term treatment may lower the risk of acute urinary retention and reduce the likelihood of requiring prostate surgery.
     
Side effects of Siloflow 8 D Tablet
Here are the steps to manage the medication-triggered Common Cold:
  • Inform your doctor about the common cold symptoms you're experiencing due to medication.
  • Your doctor may adjust your treatment plan, which could include changing your medication, adding new medications, or offering advice on managing your symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Drink plenty of fluids, such as warm water or soup, to help thin out mucus.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your symptoms don't subside or worsen, consult your doctor for further guidance.
  • A blocked nose can be relieved by drinking more water, which helps clear fluids.
  • Use saline nasal spray available over the counter to relieve blockage or blow harder to remove the mucus.
  • Use nasal strips that can be placed on the nose to widen nostrils and increase airflow.
  • Keep a humidifier around to moisten air at home/workplace.
Here are the steps to manage the medication-triggered Sinusitis (Sinus infection or Inflammation Of Sinuses):
  • Consult your doctor if you experience symptoms of sinusitis, such as nasal congestion, facial pain, or headaches, which may be triggered by your medication.
  • Your doctor may adjust your treatment plan by changing your medication, adding new medications, or providing guidance on managing your sinusitis symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • If your doctor advises, you can use nasal decongestants or saline nasal sprays to help relieve nasal congestion and sinus pressure.
  • To help your body recover, get plenty of rest, stay hydrated, and engage in stress-reducing activities. If your symptoms persist or worsen, consult your doctor for further guidance.
  • To help reduce symptoms, eat foods high in vitamin C, such as oranges, bell peppers and strawberries.
  • Lightly blow your nose to remove mucus; steer clear of blowing hard.
  • Infections can be prevented from spreading by washing hands frequently and staying away from other people.
  • If you have allergies, do your best to avoid triggering allergens that could contribute to a runny nose.
  • Don't smoke, as irritating the nasal passages can make a runny nose worse.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.

Directions for Use

Follow these step-by-step instructions to take this medication safely and effectively:

  • Swallow the tablet whole with a full glass of water.
  • Do not crush, chew, or break the tablet, as this can destroy the protective coating and irritate your mouth or throat.
  • Take the tablet with a meal, preferably at the same time every day, to ensure proper absorption and to reduce the risk of dizziness.
  • Always follow your doctor's exact instructions regarding your treatment plan. Do not stop taking this medication suddenly without consulting your healthcare provider first.
     

How Siloflow 8 D Tablet Works

Siloflow 8 D Tablet contains silodosin and dutasteride, which work together to help relieve urinary symptoms caused by an enlarged prostate. Silodosin is an alpha-blocker that relaxes the smooth muscles in the prostate gland and the neck of the bladder. This helps widen the urinary passage, making it easier for urine to flow and reducing symptoms such as difficulty starting urination, a weak urine stream, and the feeling of incomplete bladder emptying. Dutasteride is a 5-alpha reductase inhibitor that works by reducing the production of dihydrotestosterone (DHT), a hormone that contributes to prostate enlargement. Over time, lowering DHT levels helps shrink the enlarged prostate and reduces the underlying obstruction to urine flow. Together, these actions help improve urinary flow, reduce symptoms of benign prostatic hyperplasia (BPH), and support long-term prostate health.
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Alcohol

Unsafe

You are advised not to consume alcohol while taking Siloflow 8 D Tablet as it makes you pee more and can irritate your bladder and also increased dizziness and lower blood pressure.

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Pregnancy

Not applicable

Women should not use Siloflow 8 D Tablet as it is used to treat benign prostatic hyperplasia (BPH) in men only.

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Breast Feeding

Not applicable

Women should not use Siloflow 8 D Tablet as it is used to treat benign prostatic hyperplasia (BPH) in men only.

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Driving

Unsafe

Siloflow 8 D Tablet may cause dizziness. Therefore you are advised to drive and operate machinery only if you are alert.

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Liver

Caution

Siloflow 8 D Tablet should be used with caution in patients with liver disease. The dose adjustment may be needed in such patients.

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Kidney

Caution

Siloflow 8 D Tablet should be used with caution in patients with kidney disease. The dose adjustment may be needed in such patients.

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Children

Unsafe

Siloflow 8 D Tablet is not recommended for children below 18 years of age as the safety and efficacy are not established.

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Heart

Consult your doctor

Please consult your physician if you have any heart-related problems before taking Siloflow 8 D Tablet .

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Geriatrics

Caution

Siloflow 8 D Tablet should be used in elderly patients with proper monitoring and individualised care.

What if I have taken an overdose of Siloflow 8 D Tablet

Do not take more than the prescribed dose of Siloflow 8 D Tablet as it may cause overdose. Symptoms of overdose include dizziness, drowsiness, fainting, or severe decrease in blood pressure. If you suspect you have taken overdose, please consult a doctor immediately.

Diet & Lifestyle Advise

  • Limit Evening Fluid Intake: Reduce fluid consumption 2 to 4 hours before bedtime to help minimise night-time urination.
  • Avoid Bladder Irritants: Limit caffeine and alcohol, as they may worsen urinary frequency and urgency.
  • Practice Double Voiding: After urinating, wait briefly and try to urinate again to help empty the bladder more completely.
  • Stay Physically Active: Regular moderate exercise may help improve urinary symptoms associated with an enlarged prostate.
  • Be Careful with Cold Medicines: Consult your doctor or pharmacist before using decongestants or other cold remedies, as they may worsen urinary difficulties.
     
health query

Have a query?

How Soon It Starts Working

The time required for Siloflow 8 D Tablet to start to work: Siloflow 8 D Tablet ideally shows its action within 2 to 6 hours after administration. The time for which the effects of Siloflow 8 D Tablet last: The duration of action for Siloflow 8 D Tablet is unknown.

What if you forget to take Siloflow 8 D Tablet

If you miss a dose of Siloflow 8 D Tablet , take it as soon as you remember. However, if it is almost time for the next dose, skip the missed one and continue with your regular schedule. Do not take a double dose to make up for the missed one.

Storage

• Store Siloflow 8 D Tablet tablets at a controlled room temperature between 20°C and 25°C (68°F to 77°F). • Keep the tablets in their original packaging to protect them from moisture and direct light.

Drug Warnings

  • Inform Your Eye Surgeon: Tell your eye specialist if you are taking this medicine before cataract or glaucoma surgery, as it may affect the procedure.
  • Stand Up Slowly: Rise gradually from sitting or lying positions to help prevent dizziness and reduce the risk of falls.
  • Avoid Handling During Pregnancy: Pregnant women or women who may become pregnant should not handle broken or crushed tablets because the medicine may be absorbed through the skin.
  • Do Not Donate Blood: Avoid donating blood while taking Siloflow 8 D Tablet and for at least 6 months after stopping treatment.
  • Use Appropriate Contraception: Use a barrier contraceptive if your partner is pregnant or may become pregnant, as small amounts of the medicine may be present in semen.
     

Drug-Drug Interactions

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Drug-Drug Interactions

Inform your doctor if you are taking any of the following medicines, as they may interact with Siloflow 8 D Tablet :

  •  Blood pressure medicines or other alpha-blockers: May increase the risk of severely low blood pressure and extreme dizziness upon standing.
  • Erectile dysfunction medicines (such as sildenafil or tadalafil): Can cause a dangerous drop in blood pressure when taken together with this medication.
  • Strong CYP3A4 inhibitors (such as ketoconazole, ritonavir, or clarithromycin): May increase the concentration of the medicine in your body, raising the risk of severe side effects.


Drug-Food Interactions

Certain foods and beverages may affect how Siloflow 8 D Tablet works or increase the likelihood of side effects: 

  • Grapefruit and grapefruit juice: May interfere with how your body breaks down the medication, potentially increasing its level in your bloodstream and causing side effects.


Drug-Disease Interactions

Inform your doctor if you have any of the following medical conditions before taking Siloflow 8 D Tablet , as dose adjustments or additional monitoring may be required: 

  • Severe liver damage: May cause the medicine to build up in your body, increasing the risk of side effects.
  • Severe kidney damage: Can affect how the medicine is cleared from your body, requiring caution or dose adjustments.
  • Low blood pressure (hypotension): May worsen your symptoms of dizziness, lightheadedness, or fainting.
     
Silodosin + DutasterideAmprenavir
Critical
Silodosin + DutasterideCobicistat
Critical

Drug-Drug Interactions

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Silodosin + DutasterideAmprenavir
Critical
How does the drug interact with Siloflow 8 D Tablet:
Co-administration of Amprenavir and Silodosin together can increase the effect of Siloflow 8 D Tablet.

How to manage the interaction:
Taking Amprenavir and Siloflow 8 D Tablet together is not recommended, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as dizziness, lightheadedness, fainting, headache, flushing, nose congestion, or rapid heartbeat. Do not discontinue any medications without consulting a doctor.
Silodosin + DutasterideCobicistat
Critical
How does the drug interact with Siloflow 8 D Tablet:
Co-administration of Cobicistat and Siloflow 8 D Tablet together can increase the effect of Silodosin.

How to manage the interaction:
Taking Cobicistat and Siloflow 8 D Tablet together is not recommended as it can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as dizziness, lightheadedness, fainting, headache, flushing, nose congestion, or rapid heartbeat. Do not discontinue any medications without consulting a doctor.
Silodosin + DutasterideNefazodone
Critical
How does the drug interact with Siloflow 8 D Tablet:
When Siloflow 8 D Tablet and Nefazodone are taken together, may significantly increase the blood levels and effects of Silodosin.

How to manage the interaction:
Taking Nefazodone and Siloflow 8 D Tablet together is not recommended as it can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as dizziness, lightheadedness, fainting, headache, flushing (skin becomes red and hot), nose congestion, or rapid heartbeat. Do not discontinue any medications without consulting a doctor.
Silodosin + DutasterideItraconazole
Critical
How does the drug interact with Siloflow 8 D Tablet:
When Siloflow 8 D Tablet and Itraconazole are taken together, may significantly increase the blood levels and effects of Silodosin.

How to manage the interaction:
Taking Itraconazole and Siloflow 8 D Tablet together is not recommended as it can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as dizziness, lightheadedness, fainting, headache, flushing (skin becomes red and hot), nose congestion, or rapid heartbeat. Do not discontinue any medications without consulting a doctor.
Silodosin + DutasterideTelithromycin
Critical
How does the drug interact with Siloflow 8 D Tablet:
When Siloflow 8 D Tablet and Telithromycin are taken together, may significantly increase the blood levels and effects of Silodosin.

How to manage the interaction:
Taking Telithromycin and Siloflow 8 D Tablet together is not recommended as it can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as dizziness, lightheadedness, fainting, headache, flushing (skin becomes red and hot), nose congestion, or rapid heartbeat. Do not discontinue any medications without consulting a doctor.
Silodosin + DutasterideDelavirdine
Critical
How does the drug interact with Siloflow 8 D Tablet:
When Siloflow 8 D Tablet and delavirdine are taken together, may significantly increase the blood levels and effects of Silodosin.

How to manage the interaction:
Taking delavirdine and Siloflow 8 D Tablet together is not recommended as it can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as dizziness, lightheadedness, fainting, headache, flushing (skin becomes red and hot), nose congestion, or rapid heartbeat. Do not discontinue any medications without consulting a doctor.
Silodosin + DutasterideNelfinavir
Critical
How does the drug interact with Siloflow 8 D Tablet:
When Siloflow 8 D Tablet and Nelfinavir are taken together, may significantly increase the blood levels and effects of Silodosin.

How to manage the interaction:
Taking Nelfinavir and Siloflow 8 D Tablet together is not recommended as it can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as dizziness, lightheadedness, fainting, headache, flushing (skin becomes red and hot), nose congestion, or rapid heartbeat. Do not discontinue any medications without consulting a doctor.
Silodosin + DutasterideVoriconazole
Critical
How does the drug interact with Siloflow 8 D Tablet:
When Siloflow 8 D Tablet and Voriconazole are taken together, may significantly increase the blood levels and effects of Silodosin.

How to manage the interaction:
Taking Voriconazole and Siloflow 8 D Tablet together is not recommended as it can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as dizziness, lightheadedness, fainting, headache, flushing (skin becomes red and hot), nose congestion, or rapid heartbeat. Do not discontinue any medications without consulting a doctor.
Silodosin + DutasterideClarithromycin
Critical
How does the drug interact with Siloflow 8 D Tablet:
Taking Siloflow 8 D Tablet with Clarithromycin may significantly increase the blood levels and effects of Silodosin.

How to manage the interaction:
Taking Clarithromycin and Siloflow 8 D Tablet together is not recommended as it can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as dizziness, lightheadedness, fainting, headache, flushing, nose congestion, or rapid heartbeat. Do not discontinue any medications without consulting a doctor.
Silodosin + DutasterideTelaprevir
Critical
How does the drug interact with Siloflow 8 D Tablet:
When Siloflow 8 D Tablet and Telaprevir are taken together, may significantly increase the blood levels and effects of Silodosin.

How to manage the interaction:
Taking Telaprevir and Siloflow 8 D Tablet together is not recommended as it can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as dizziness, lightheadedness, fainting, headache, flushing (skin becomes red and hot), nose congestion, or rapid heartbeat. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[GENITOURINARY TRACT AGENTS]

FAQs

Siloflow 8 D Tablet is used to treat the symptoms of Benign Prostatic Hyperplasia (BPH) in men.
No, Siloflow 8 D Tablet should not be taken along with blood-pressure-lowering medicines. Siloflow 8 D Tablet may cause a sudden drop in your blood pressure which could lead to dizziness or fainting. Therefore, if Siloflow 8 D Tablet is taken along with blood pressure lowering medicines, it could lead to a severe decrease in blood pressure which could be lethal.
Yes, Siloflow 8 D Tablet may cause dizziness. You are advised not to drive or operate heavy machinery after taking Siloflow 8 D Tablet as it may cause dizziness. Drive or operate machinery only if you are alert.
Siloflow 8 D Tablet is a combination of two drugs, namely; Silodosin and Dutasteride used to treat the symptoms of benign prostatic hyperplasia (BPH) in adults with an enlarged prostate gland. Silodosin belongs to a class of alpha-1 receptors (located in prostate and bladder) blocker that works by blocking the action of alpha-1 receptors and causes smooth muscle relaxation in the bladder and prostate. Dutasteride belongs to a class of 5-alpha reductase that works by blocking the action of a 5-alpha reductase enzyme, resulting in a shrink of the size of the prostate gland. Siloflow 8 D Tablet reduces the BPH symptoms and improves your ability to urinate.
The side effects of Siloflow 8 D Tablet include dizziness, headache, diarrhoea, nasal congestion (stuffy nose), impotence (erectile dysfunction) and ejaculation disorder. If these side effects persist or worsen, please consult your doctor.
You should take Siloflow 8 D Tablet for as long as it is prescribed by your doctor. It is usually advised for long term use. If you discontinue Siloflow 8 D Tablet in the midway, it may worsen your condition.
Take Siloflow 8 D Tablet as advised by your doctor. Swallow it as a whole with a glass of water. Do not crush, chew or break it. Take it at the same time every day. Do not miss doses or stop the treatment before the prescribed duration, even if you feel well.
Siloflow 8 D Tablet is effective if used in the dose and duration prescribed by your doctor. Even if you see improvement in your condition, do not stop using Siloflow 8 D Tablet too early as the symptoms may return or worsen.
Benign prostatic hyperplasia (BPH) also known as prostate gland enlargement is a common condition in older men. The symptoms include urgent or frequent need to urinate, inability to completely empty the bladder and increased frequency of urination at night (nocturia).
The use of Siloflow 8 D Tablet is contraindicated in patients who are allergic to any ingredients of it. Siloflow 8 D Tablet should be used with caution in patients with underlying liver or kidney disease. If you have any concerns, consult your doctor.
Store Siloflow 8 D Tablet in a cool, dry and dark place. Keep it out of reach of children.
Siloflow 8 D Tablet is safe if used in the dose and duration prescribed by your doctor. Take it exactly as advised and do not miss any dose. Follow your doctor's instructions carefully and if any of the side effects bother you, inform your doctor.
It is best to take Siloflow 8 D Tablet after meals. Swallow it as whole with water. Do not open, chew or crush it. Follow your doctor’s instructions carefully.
You may notice an improvement in your urinary flow within a few days due to the muscle-relaxing effect. However, it can take several weeks or even months for the prostate-shrinking effect to become fully noticeable. Talk to your doctor if your symptoms do not improve after a few weeks.
o, Siloflow 8 D Tablet is prescribed only for men with an enlarged prostate. Women, especially those who are pregnant or may become pregnant, must not take this medication or handle the tablets, as it can cause serious developmental issues in a male fetus.
The medicine remains in your blood for a long time. If a pregnant woman receives your donated blood, the active ingredients could cause birth defects in her developing male baby. You must wait at least 6 months after stopping the medicine before donating blood.
Yes, this medication can cause sexual side effects, such as reduced semen during ejaculation (retrograde ejaculation) or difficulty maintaining an erection. These effects are usually temporary and stop after the medication is discontinued. Talk to your doctor if you have concerns.
It is best to limit or avoid alcohol while taking this medicine. Alcohol can worsen dizziness and lightheadedness caused by the medication and can also irritate your bladder, worsening your urinary symptoms. Talk to your doctor for personalised advice.
If you feel dizzy or lightheaded, sit or lie down immediately until the feeling passes. To prevent this, avoid standing up too quickly from a sitting or lying position. If dizziness persists or causes fainting, contact your doctor right away.
Do not stop taking your medication without consulting your doctor. However, you must inform your eye surgeon well in advance of any cataract or glaucoma surgery that you are taking Siloflow 8 D Tablet , as it can affect your pupils during the procedure.
You should take Siloflow 8 D Tablet with a meal, preferably at the same time every day. Taking it with food helps your body absorb the medication properly and reduces the risk of side effects like dizziness. Talk to your doctor or pharmacist if you have trouble taking it with food.

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Country of origin

India

Manufacturer/Marketer address

Nephurocare Pharma Pvt. Ltd. , E-609, Titanium City Center, Nr. 100Ft Road, Anand Nagar, Satellite, Ahmedabad - 380015, Gujarat, India
Other Info - SIL0571
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