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Zolfresh 5 Tablet 15's
Zolfresh 5 Tablet 15's
Zolfresh 5 Tablet 15's
Zolfresh 5 Tablet 15's
Zolfresh 5 Tablet 15's

Zolfresh 5 Tablet is used in the short-term treatment of insomnia. It contains Zolpidem which relaxes muscles, reduces anxiety, and helps to fall asleep. Some people may experience dizziness, diarrhoea, drowsiness, headache, nausea, vomiting, nose or throat infections, tiredness, stomach pain, double vision, and back pain. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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Health Queries

I'm having trouble falling asleep and can't get a good night's sleep. Exams are coming up. Please assist

Y. Lakshmi Thulasi

Y. Lakshmi Thulasi

Pharm-D (Post baccalaureate)

If exams are causing sleep trouble, focus on calming your mind rather than using strong medicines, keep a fixed sleep time, avoid screens and caffeine at night, and try simple relaxation like deep breathing or light reading before bed.

My doctor prescribed 5 mg of zolfresh, but I have anxiety. Could you help suggest some medication?

Y. Lakshmi Thulasi

Y. Lakshmi Thulasi

Pharm-D (Post baccalaureate)

Zolfresh helps sleep but does not treat anxiety, so your doctor may consider adding a safer long-term option like escitalopram or sertraline, and sometimes buspirone for anxiety control instead of increasing sleeping pills.

She may have a sleep apnea?issue that prevents her from getting a good night's sleep. How to reduce it?

Y. Lakshmi Thulasi

Y. Lakshmi Thulasi

Pharm-D (Post baccalaureate)

If she may have Sleep apnea, help reduce it by maintaining a healthy weight, sleeping on the side instead of the back, and avoiding alcohol or sedatives at night as they worsen breathing. Most importantly, consult a doctor for proper evaluation

Despite taking 2 mg of Attivan and 0.5 mg of Alprex after dinner, I have trouble falling asleep. What should I do?

Y. Lakshmi Thulasi

Y. Lakshmi Thulasi

Pharm-D (Post baccalaureate)

Taking both Ativan (lorazepam) and Alprex together can increase tolerance and reduce effect over time, so avoid adding more doses on your own and don?t mix further sedatives. Instead, consult your doctor to review and adjust your medicines safely

How does stress affect health?

Bayyarapu Mahesh Kumar

Bayyarapu Mahesh Kumar

M Pharmacy

Stress affects health by disrupting the body’s normal hormonal and nervous system balance, which can increase the risk of heart disease, diabetes, anxiety, depression, and weaken the immune system, making it harder to fight infections.

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Side effects of Zolfresh 5 Tablet
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
  • Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
  • Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
  • Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
  • Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • Get enough sleep. Maintain a regular sleep cycle.
  • Eat a healthy diet and exercise regularly.
  • Manage stress with yoga or meditation.
  • Limit alcohol and caffeine.
  • Avoid driving or operating machinery unless you are alert.
  • Uncoordinated muscle movements need immediate medical attention.
  • Observe your movements and try to understand and control the particular movement.
  • Regularly do strengthening exercises to improve blood flow throughout the body and avoid involuntary movements.
  • Implement massage techniques to enhance blood flow to organs.
  • Take a balanced diet and quit smoking.
  • Practice yoga and meditation to improve thought processes and reduce uncontrolled and involuntary movements.
  • Hallucination is a major psychotic disorder that needs immediate medical attention.
  • Acknowledge your experience and put effort to control hallucinations. You can share what is being seen with a therapist to know whether they are real or imaginary.
  • Avoid smoking and alcohol intake as it can worsen the condition and increase your imagination.
  • Practice meditation and yoga to avoid anxiety, which can be one of the leading causes of hallucinations.
  • Talk to your dietician and consume food that can improve your mental health.

Drug-Drug Interactions

verifiedApollotooltip
ZolpidemSodium oxybate
Critical
ZolpidemSufentanil
Severe

Drug-Drug Interactions

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ZolpidemSodium oxybate
Critical
How does the drug interact with Zolfresh 5 Tablet:
Using sodium oxybate together with Zolfresh 5 Tablet can significantly increase the risk of severity of low blood pressure, breathing difficulties, fainting and unconsciousness.

How to manage the interaction:
Taking Sodium oxybate with Zolfresh 5 Tablet is generally avoided as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you notice any symptoms of headache, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate consult a doctor immediately. You should refrain from operating any dangerous machinery or driving a car. Do not stop using any medications without talking to a doctor.
ZolpidemSufentanil
Severe
How does the drug interact with Zolfresh 5 Tablet:
Using Zolfresh 5 Tablet together with Sufentanil can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking Sufentanil and Zolfresh 5 Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience dizziness, drowsiness, difficulty concentrating, impairment in judgment, or reaction speed, consult a doctor. You should refrain from using dangerous machinery or driving a car. Do not discontinue any medications without consulting a doctor.
ZolpidemCiprofloxacin
Severe
How does the drug interact with Zolfresh 5 Tablet:
Coadministration of Zolfresh 5 Tablet with ciprofloxacin can increase the blood levels and effects of Zolfresh 5 Tablet. This can increase the risk or severity of side effects.

How to manage the interaction:
Although taking ciprofloxacin and Zolfresh 5 Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience drowsiness, dizziness, or sleep disturbances, consult a doctor. Do not discontinue any medications without consulting a doctor.
ZolpidemFentanyl
Severe
How does the drug interact with Zolfresh 5 Tablet:
Using Zolfresh 5 Tablet together with Fentanyl can cause central nervous system depression.

How to manage the interaction:
Although taking Fentanyl and Zolfresh 5 Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult a doctor if you experience dizziness, sleepiness, difficulty concentrating, and impaired judgment. Do not discontinue any medications without consulting a doctor.
ZolpidemButorphanol
Severe
How does the drug interact with Zolfresh 5 Tablet:
Using Zolfresh 5 Tablet together with Butorphanol can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking Butorphanol and Zolfresh 5 Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience dizziness, drowsiness, difficulty concentrating, and impairment in judgment, or reaction speed, avoid driving or operating hazardous machinery consult a doctor. Do not stop using any medications without a doctor's advice.
ZolpidemPentazocine
Severe
How does the drug interact with Zolfresh 5 Tablet:
Using Zolfresh 5 Tablet together with Pentazocine can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking Pentazocine and Zolfresh 5 Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience dizziness, drowsiness, difficulty concentrating, impairment in judgment, or reaction speed, consult a doctor. You should refrain from using dangerous machinery or driving a car. Do not discontinue any medications without consulting a doctor.
ZolpidemPindolol
Severe
How does the drug interact with Zolfresh 5 Tablet:
Taking Zolfresh 5 Tablet with Pindolol may increase the risk of low blood pressure.

How to manage the interaction:
Although taking Pindolol and Zolfresh 5 Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience headache, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
ZolpidemPethidine
Severe
How does the drug interact with Zolfresh 5 Tablet:
Taking Zolfresh 5 Tablet with Pethidine may increase the risk of central nervous system depression, which can lead to breathing difficulty and unconsciousness.

How to manage the interaction:
Although taking Pethidine and Zolfresh 5 Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience dizziness, drowsiness, difficulty concentrating, impairment in judgment, or reaction speed, consult a doctor. Do not discontinue any medications without consulting a doctor.
ZolpidemCodeine
Severe
How does the drug interact with Zolfresh 5 Tablet:
Using Zolfresh 5 Tablet together with Codeine can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking codeine and Zolfresh 5 Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience dizziness, drowsiness, difficulty concentrating, impairment in judgment, or reaction speed, consult a doctor. Do not discontinue any medications without consulting a doctor.
ZolpidemTramadol
Severe
How does the drug interact with Zolfresh 5 Tablet:
Using Zolfresh 5 Tablet together with Tramadol can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking Tramadol and Zolfresh 5 Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience dizziness, drowsiness, difficulty concentrating, impairment in judgment, or reaction speed, consult a doctor. You should refrain from using dangerous machinery or driving a car. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Nov 18, 2025 | 7:34 AM IST

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