Bdparp 150 Tablet 28's
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28 ₹20756.3
(₹741.3 per unit)
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56 ₹41512.5
(₹741.29 per unit)
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MRP ₹25312.5
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About Bdparp 150 Tablet
Bdparp 150 Tablet is an 'anti-cancer' drug used to treat various cancers, including ovarian, breast, pancreatic, and prostate. Cancer is a condition where cells in a specific body part grow and reproduce uncontrollably. The cancerous cells can attack and destroy surrounding healthy tissue, including organs.
Bdparp 150 Tablet contains Olaparib, a targeted drug called a PARP inhibitor. PARP (polyadenosine 5’-diphosphoribose polymerase) is a protein that helps damaged cells repair themselves. Olaparib stops PARP working. Some cancer cells rely on PARP to keep their DNA healthy. So, the cancer cells die when Olaparib stops PARP from repairing DNA damage.
Use this medicine as directed by your doctor. You may sometimes experience shortness of breath (dyspnoea), feeling very tired, pale skin or fast heartbeat, anaemia, feeling sick (nausea), being sick (vomiting), indigestion or heartburn (dyspepsia), loss of appetite, headache, changes in taste of foods (dysgeusia), feeling dizzy, cough and diarrhoea. Most of these side effects may gradually resolve over time. However, if the side effects persist or worsen, consult your doctor.
To treat your condition effectually, continue taking Bdparp 150 Tablet for as long as your doctor has prescribed. Do not stop using the Bdparp 150 Tablet midway. Talk to your doctor before taking Bdparp 150 Tablet if you have severe allergic reactions to Bdparp 150 Tablet or other medicines or suffer from severe infections, renal dysfunction, hepatic disorders and blood cell counts are too low. Avoid taking Bdparp 150 Tablet if you are pregnant or breastfeeding because this Bdparp 150 Tablet can cause harmful effects on the unborn baby. Both women and men using this Bdparp 150 Tablet should use birth control to avoid pregnancy. While on Bdparp 150 Tablet treatment, you should avoid eating grapefruit, Seville oranges or consuming grapefruit juice since it can affect how the medicine works.
Uses of Bdparp 150 Tablet
Bdparp 150 Tablet is used in the treatment of Ovarian cancer, breast cancer, pancreatic cancer, and prostate cancer. The detailed uses of Bdparp 150 Tablet are as follows:
- Ovarian Cancer: Bdparp 150 Tablet helps in maintenance treatment for advanced epithelial ovarian, fallopian tube, or primary peritoneal cancer after response to platinum-based chemotherapy and especially effective in patients with BRCA mutations or homologous recombination deficiency (HRD).
- Breast Cancer: Bdparp 150 Tablet is used for HER2-negative, BRCA-mutated metastatic or high-risk early breast cancer and used after chemotherapy and sometimes endocrine therapy.
- Pancreatic Cancer: Bdparp 150 Tablet helps in maintenance treatment for germline BRCA-mutated metastatic pancreatic cancer that hasn’t progressed after platinum-based chemotherapy.
- Prostate Cancer: Bdparp 150 Tablet is for BRCA-mutated metastatic castration-resistant prostate cancer, often after prior hormonal therapy.
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Directions for Use
- Bdparp 150 Tablet can be taken with or without food as prescribed by your doctor.
- It is usually taken twice a day in the morning and evening, or as prescribed by your doctor.
- Swallow the medicine as a whole with a glass of water.
- Do not break, crush or chew Bdparp 150 Tablet .
Key Benefits
Bdparp 150 Tablet belongs to a group of medicines known as 'anti-cancer' drugs used to treat various cancers, including Ovarian, breast, pancreatic, and prostate. Bdparp 150 Tablet contains Olaparib, a targeted drug called a PARP inhibitor. PARP (polyadenosine 5’-diphosphoribose polymerase) is a protein that helps damaged cells repair themselves. Olaparib stops PARP working. Some cancer cells rely on PARP to keep their DNA healthy. So, the cancer cells die when Olaparib stops PARP from repairing DNA damage.
How Bdparp 150 Tablet Works
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- Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
- Divide your daily food intake into smaller, more frequent meals to reduce nausea.
- Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
- Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
- Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
- Use ginger (tea, ale, or candies) to help relieve nausea.
- Get adequate rest and also avoid strenuous activities that can worsen nausea.
- Talk to your doctor about taking anti-nausea medication if your nausea is severe.
- Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
- Rest well; get enough sleep.
- Eat a balanced diet and drink enough water.
- Manage stress with yoga and meditation.
- Limit alcohol and caffeine.
- Physical activities like walking or jogging might help boost energy and make you feel less tired.
- Include iron-rich foods like dark leafy vegetables, lean red meat, legumes and fish in your diet.
- Consume vitamin C-rich foods as they aid iron absorption.
- Limit tea, cocoa, and coffee as these can slow iron absorption.
- Exercise regularly; however, do not overdo it.
- Preventing Vomiting (Before it Happens)
- Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
- Having a small meal before taking your medication can help reduce nausea and vomiting.
- Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
- Managing Vomiting (If it Happens)
- Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
- What to Do if Vomiting Persists
- Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
- Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
- Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
- Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
- Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
- Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
- Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
- Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
- Hydrate your body: Drink enough water to prevent dehydration and headaches.
- Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
- Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
- Take rest: lie down in a quiet, dark environment.
- Cold or warm compresses can help reduce tension.
- Stay Upright: Maintain good posture to keep symptoms from getting worse.
- To treat headaches naturally, try acupuncture or massage therapy.
- Over-the-counter pain relievers include acetaminophen and ibuprofen.
- Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
- Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
- Frequent Headaches: If you get reoccurring headaches, consult your doctor.
- Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
- Regularly brush and floss your teeth.
- Rinse your mouth with water and baking soda a solution to neutralize acid in the mouth. This makes your food taste as it should.
- Drink plenty of water or non-caffeinated drinks to prevent dry mouth which may lead to altered taste.
- Try ginger, peppermint, fruit or green teas, lemonade, ginger ale or fruit juice to help mask unpleasant tastes.
- Try sucking on sugar-free ice pops or ice cubes to prevent dry mouth.
What if I have taken an overdose of Bdparp 150 Tablet
Drug Warnings
Always take this medicine exactly as your doctor or healthcare professional has told you. To treat your condition effectually, continue taking Bdparp 150 Tablet for as long as your doctor has prescribed. Do not stop Bdparp 150 Tablet midway. Talk to your doctor before taking Bdparp 150 Tablet if you have severe allergic reactions to Bdparp 150 Tablet or other medicines or suffer from any medical illness. Avoid taking Bdparp 150 Tablet if you are pregnant or breastfeeding because this Bdparp 150 Tablet can cause harmful effects on the unborn baby. Both women and men using this Bdparp 150 Tablet should use birth control to avoid pregnancy. Do not start Bdparp 150 Tablet unless patients have recovered from haematological damage induced by previous chemotherapy (Grade 1). Check full blood count for cytopenia at baseline and monthly afterwards for clinically significant changes during treatment. For persistent haematological toxicity, discontinue Bdparp 150 Tablet and monitor blood count weekly until recovery. Do not receive any immunization or vaccination without your doctor's approval while taking the Bdparp 150 Tablet .
Drug-Drug Interactions
Drug-Drug Interactions
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Using Atazanavir and Bdparp 150 Tablet can increase the blood levels of Bdparp 150 Tablet. This can increase the risk and/or severity of side effects Bdparp 150 Tablet.
How to manage the interaction:
Combining Atazanavir and Bdparp 150 Tablet can lead to an interaction, but it can be taken if your doctor advises. However, if you experience paleness, fatigue, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhoea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact the doctor immediately. Do not discontinue any medications without consulting your doctor.
Using Darunavir and Bdparp 150 Tablet can increase the blood levels of Bdparp 150 Tablet. This can increase the risk and/or severity of side effects such as nausea, vomiting, diarrhea, indigestion, loss of appetite, abdominal pain or discomfort, lung problems, and impaired bone marrow function resulting in low numbers of different types of blood cells.
How to manage the interaction:
Combining Darunavir and Bdparp 150 Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like paleness, fatigue, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact the doctor immediately. Do not discontinue any medications without first consulting your doctor.
Using Ciprofloxacin and Bdparp 150 Tablet can increase the blood levels of Bdparp 150 Tablet. This can increase the risk and severity of side effects.
How to manage the interaction:
Although there is a interaction between ciprofloxacin and Bdparp 150 Tablet, it can be taken if advised by your doctor. However, if you experience any symptoms like paleness, fatigue, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact the doctor immediately. Do not discontinue any medications without consulting a doctor.
Phenobarbital can drastically lower Bdparp 150 Tablet levels in the blood, making the medicine less effective in treating the cancer.
How to manage the interaction:
Although taking phenobarbital and Bdparp 150 Tablet together can possibly result in an interaction, it can be taken if a doctor has prescribed it. Do not stop using any medications without a doctor's advice.
Using Letermovir and Bdparp 150 Tablet can increase the blood levels of Bdparp 150 Tablet. This can increase the risk and/or severity of side effects such as nausea, vomiting, diarrhea, indigestion, loss of appetite, abdominal pain or discomfort, lung problems, and impaired bone marrow function resulting in low numbers of different types of blood cells.
How to manage the interaction:
Combining Letermovir and Bdparp 150 Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like paleness, fatigue, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact the doctor immediately. Do not discontinue any medications without first consulting your doctor.
Taking Armodafinil and Bdparp 150 Tablet may reduce the blood levels of Bdparp 150 Tablet, which may reduce the effect of Bdparp 150 Tablet.
How to manage the interaction:
Although there is a possible interaction between Armodafinil and Bdparp 150 Tablet, you can take these medicines together if prescribed by a doctor. Contact a doctor if your symptoms do not improve. Do not stop using any medications without consulting a doctor.
Using Certolizumab together with Bdparp 150 Tablet may increase the risk of infections.
How to manage the interaction:
Combining Certolizumab and Bdparp 150 Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact the doctor immediately. Do not discontinue any medications without first consulting your doctor.
When Bdparp 150 Tablet is taken with Fosaprepitant, can increase the levels of Bdparp 150 Tablet in the body. This can increase the risk or severity of side effects.
How to manage the interaction:
Taking Bdparp 150 Tablet with Fosaprepitant together can result in an interaction, but it can be taken if your doctor has advised it. If you notice any of these symptoms paleness, fatigue, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, it's a good idea to call a doctor right away. Do not discontinue any medications without consulting a doctor.
Taking Ritonavir and Bdparp 150 Tablet may significantly increase the blood levels of Bdparp 150 Tablet.
How to manage the interaction:
There may be a possibility of interaction between Bdparp 150 Tablet and Ritonavir, but it can be taken if prescribed by a doctor. However, if you experience tiredness, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, red or inflamed skin, body sores, and pain or burning during urination contact a doctor. Do not stop using any medications without talking to a doctor.
Using Ceritinib and Bdparp 150 Tablet can increase the blood levels of Bdparp 150 Tablet.
How to manage the interaction:
Although there is a interaction between ceritinib and Bdparp 150 Tablet, it can be taken if advised by your doctor. However, if you experience any symptoms like paleness, weakness, dizziness, fainting, unusual bruising or bleeding, fever, chills, loose stools, sore throat, muscle aches, shortness of breath, blood in phlegm, red or inflamed skin, body sores, and pain or burning during urination, contact the doctor. Do not discontinue any medications without consulting a doctor.
Drug-Food Interactions
Drug-Food Interactions
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Diet & Lifestyle Advise
- De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
- Performing yoga may also help in improving both physical and mental health.
- Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
- Eat a healthy diet and exercise regularly to maintain proper weight.
- Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs.
- Get optimal sleep; rest well.
- Avoid smoking and alcohol consumption.
- Avoid fast, fried, processed meats, refined carbs and added sugars.
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Alcohol
Safe if prescribed
Avoid alcohol consumption while on treatment with Bdparp 150 Tablet .
Pregnancy
Consult your doctor
Bdparp 150 Tablet should not be used during pregnancy because it can harm your fetus (newborn baby). Both women of childbearing potential and men must use an effective contraception method while taking Bdparp 150 Tablet and at least for six months later treatment. Your doctor will weigh the benefits and risks before prescribing this medicine.
Breast Feeding
Consult your doctor
Do not breastfeed during this treatment because the medicine may pass into your milk. Doctors normally advise against breastfeeding throughout this treatment and for one month after the final medication is taken.
Driving
Safe if prescribed
Bdparp 150 Tablet may affect your reactions and your ability to drive. Do not drive and/or operate machines that require your alertness.
Liver
Consult your doctor
In patients with mild or moderate liver impairment, there is no need to alter the initial dose. There is no information available on patients with severe liver impairment.
Kidney
Consult your doctor
In patients with mild or moderate kidney impairment, there is no need to alter the initial dose. There is no information available on patients with severe kidney impairment.
Children
Safe if prescribed
The safety and effectiveness of Bdparp 150 Tablet in pediatric patients have not been established.
Heart
Please consult your doctor before receiving Bdparp 150 Tablet if you have pre-existing heart problems. Your doctor will prescribe Bdparp 150 Tablet if the benefits outweigh the risks.
Geriatrics
Consult your doctor
Please consult a doctor before administering Bdparp 150 Tablet to geriatric patients. Your doctor will prescribe Bdparp 150 Tablet if the benefits outweigh the risks.
FAQs
Bdparp 150 Tablet is used to treat ovarian, breast, pancreatic, and prostate cancers.
Bdparp 150 Tablet contains Olaparib, a targeted drug called a PARP inhibitor. PARP is a protein that helps damaged cells to repair themselves. Olaparib stops PARP working. Some cancer cells rely on PARP to keep their DNA healthy. So, the cancer cells die when Olaparib stops PARP from repairing DNA damage.
If you are allergic to Olaparib or any other ingredients in this medication, are breastfeeding, or have too low blood cell counts, you should not use Bdparp 150 Tablet .
Yes, Bdparp 150 Tablet can cause low neutrophils levels, a type of white blood cells that help fight infections. If your white blood cells become low, you can be at higher risk for infections. Tell your doctor if you develop a fever or have an infection.
Do not have immunizations/vaccinations without talking to your doctor first. Also, avoid contact with people who recently had immunizations /vaccinations.
Bdparp 150 Tablet is not a traditional chemotherapy pill. It's a targeted therapy, also known as a PARP inhibitor, which works differently from chemotherapy.
When taking Bdparp 150 Tablet , avoid or limit foods high in grapefruit or grapefruit juice, as these can interact with the medication. Additionally, consult your doctor or pharmacist for personalized dietary advice.
The duration of Bdparp 150 Tablet treatment can vary depending on the type of cancer being treated and the patient's response to the medication. Generally, Bdparp 150 Tablet is taken until disease progression, unacceptable toxicity, or completion of a specified treatment period. Therefore, follow your doctor's instructions carefully.
Before taking Bdparp 150 Tablet , inform your doctor about all your medical conditions, sensitivities, and medications. Also, mention if you're pregnant, planning to become pregnant, or breastfeeding. This will ensure safe use and help avoid any potential interactions.
Bdparp 150 Tablet can interact with other medications, so do not use any other medications unless your doctor advises. Your doctor will check for potential interactions and advise you on how to take them safely with Bdparp 150 Tablet .
No, Bdparp 150 Tablet is not recommended for use during pregnancy and breastfeeding, and it causes unwanted side effects. However, please consult your doctor if you have any concerns.
The common side effects of Bdparp 150 Tablet are feeling very tired, pale skin, feeling sick (nausea), being sick (vomiting), indigestion or heartburn (dyspepsia), loss of appetite, headache, changes in taste of foods (dysgeusia), feeling dizzy, cough and diarrhoea. Please consult your doctor if any of these side effects persist or worsen.
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Reference
- https://www.myeloma.org.uk/wp-content/uploads/2023/04/Myeloma-UK-Panobinostat-Treatment-Guide.pdf
- https://www.lynparza.com/
- https://medlineplus.gov/druginfo/meds/a614060.html#:~:text=Olaparib%20is%20used%20alone%20or,tissue%20that%20lines%20the%20abdomen)
- https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/208558s001lbl.pdf
- https://www.medicines.org.uk/emc/product/9204/pil#gref
- https://reference.medscape.com/drug/lynparza-olaparib-999934
- https://www.medicines.org.uk/emc/files/pil.9204.pdf
- https://www.lynparzahcp.com/
- https://www.cancerresearchuk.org/about-cancer/treatment/drugs/olaparib-lynparza#:~:text=Olaparib%20stops%20PARP%20working.&text=healthy.,damage%2C%20the%20cancer%20cells%20die.
- https://www.lynparza.com/what-is-lynparza.html
- https://www.drugs.com/drug-interactions/olaparib-index.html?filter=3
