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Manufacturer/Marketer :

Natco Pharma Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Dabigat 110 Capsule

Dabigat 110 Capsule is used to prevent and treat the risk of stroke, heart attack in patients with atrial fibrillation (irregular heart rhythm) by reducing blood clot formation. It is also used to prevent deep vein thrombosis (blood clots in leg veins) and pulmonary embolism (blood clots in the lung).

Dabigat 110 Capsule contains Dabigatran etexilate that works by inhibiting the production of clotting factor Xa, also called thrombin. This prevents the conversion of fibrinogen (soluble protein) to fibrin (insoluble protein), thereby preventing blood clots.

You may experience bleeding, anaemia (low number of red blood cells), nausea, stomach pain, and vomiting. Most of these side effects do not require medical attention. However, talk to your doctor if you experience these side effects persistently.

If you are known to be allergic to Dabigat 110 Capsule or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to consult a doctor before using Dabigat 110 Capsule . If you have a stomach ulcer, kidney or liver problems, high blood pressure, or bleeding problems, inform your doctor before taking Dabigat 110 Capsule .

Uses of Dabigat 110 Capsule

Dabigat 110 Capsule is used in the prevention of blood clot formation, deep vein thrombosis, and pulmonary embolism. The detailed uses of Dabigat 110 Capsule are as follows:

  • Stroke Prevention: Dabigat 110 Capsule is used especially in patients with non-valvular atrial fibrillation.
  • Deep Vein Thrombosis (DVT): Dabigat 110 Capsule treats and prevents clots in the legs.
  • Pulmonary Embolism (PE): Dabigat 110 Capsule prevents clots from traveling to the lungs.
  • Post-Surgical Clot Prevention: Dabigat 110 Capsule is used in clot prevention after hip or knee replacement surgery.
  • Recurrent Clot Prevention: Dabigat 110 Capsule reduces risk of DVT/PE recurrence.

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Directions for Use

  • Dabigat 110 Capsule can be taken with or without food.
  • It is usually taken twice daily, or as prescribed by your doctor.
  • Swallow the whole Dabigat 110 Capsule with a glass of water.
  • Do not break, chew, or open it.

Medicinal Benefits

  • Dabigat 110 Capsule is primarily used to prevent and treat the risk of stroke and heart attack by reducing blood clot formation.
  • It makes the blood flow easily through the veins, making it less likely to form a serious blood clot. Thus, Dabigat 110 Capsule helps prevent blood clots, thereby reducing the risk of heart attack/stroke.
  • It also reduces the risk of getting clots in people who have undergone knee or hip replacement surgeries. Dabigat 110 Capsule works by stopping the action of the clotting factor (thrombin).
  • Dabigat 110 Capsule prevents the conversion of fibrinogen (soluble protein) to fibrin (insoluble protein), thereby preventing blood clots.
  • Reduces the risk of stroke in persons with atrial fibrillation (irregular heartbeat).

How Dabigat 110 Capsule Works

Dabigat 110 Capsule contains Dabigatran etexilate that works by inhibiting the production of clotting factor Xa, also called thrombin. This prevents the conversion of fibrinogen (a soluble protein) to fibrin (an insoluble protein), thereby preventing blood clots. It facilitates the smooth flow of blood through the veins, reducing the likelihood of forming a serious blood clot. Thus, Dabigat 110 Capsule helps prevent blood clots, thereby reducing the risk of heart attacks and strokes.

Storage

• Store in a cool and dry place away from sunlight. • Keep Dabigat 110 Capsule out of the sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Dabigat 110 Capsule
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
  • Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
  • Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
  • Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
  • Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
  • Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
  • Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
  • Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
  • Avoid other medicines that increase the risk of bleeding.
  • Use an electric razor and a soft-bristled toothbrush.
  • Monitor for signs of bleeding like bleeding gums, unusual bruising, blood in stool, nosebleeds, or heavy menstrual bleeding.
  • If you experience severe bleeding, apply direct pressure on the wound and consult a doctor promptly.
  • If the risk of bleeding is high, discuss with your doctor about possibility of switching to different medicine with a lower bleeding risk.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.

What if I have taken an overdose of Dabigat 110 Capsule

Please do not exceed the recommended dose, as it might cause serious side effects. Signs and symptoms of an overdose of Dabigat 110 Capsule may include an increased risk of bleeding. If you suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

  • If you are known to be allergic to Dabigat 110 Capsule or any other medicines, please tell your doctor.
  • Do not stop taking this medicine on your own. Discontinuing Dabigat 110 Capsule may worsen your condition and increase the risk of heart attack and stroke.
  • Dabigat 110 Capsule is not recommended for children less than 18 years of age, as the Safety and effectiveness have not been established.
  • If you have an artificial heart valve, stomach ulcer, kidney/liver problems, high blood pressure, or bleeding problems, inform your doctor before taking Dabigat 110 Capsule .
  • Avoid consumption of alcohol while taking Dabigat 110 Capsule as it may increase the risk of stomach bleeding.
  • If you are pregnant or breastfeeding, it is advised to consult a doctor before using Dabigat 110 Capsule .
  • You should inform the doctor that you are taking Dabigat 110 Capsule if you are due to undergo surgery.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Dabigat 110 Capsule:
When Mifepristone is taken with Dabigat 110 Capsule, it may increase the risk of severe vaginal bleeding in women.

How to manage the interaction:
Taking Mifepristone with Dabigat 110 Capsule is not recommended, but it can be taken if prescribed by the doctor. However, if you experience heavy, persistent vaginal bleeding, consult the door. Do not stop using any medications without talking to a doctor.
How does the drug interact with Dabigat 110 Capsule:
Taking Dabigat 110 Capsule with Tolmetin can increase the risk of bleeding leading to serious blood loss.

How to manage the interaction:
Taking Dabigat 110 Capsule with Tolmetin together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Dabigat 110 Capsule:
Taking Dabigat 110 Capsule with Reteplase can increase the risk of bleeding leading to serious blood loss.

How to manage the interaction:
Taking Dabigat 110 Capsule with Reteplase together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Dabigat 110 Capsule:
Using Indomethacin with Dabigat 110 Capsule can increase the risk of bleeding.

How to manage the interaction:
Taking Indometacin with Dabigat 110 Capsule together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Dabigat 110 Capsule:
Taking Dabigat 110 Capsule with Tenecteplase can increase the risk of bleeding leading to serious blood loss.

How to manage the interaction:
Taking Dabigat 110 Capsule with Tenecteplase together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
Severe
How does the drug interact with Dabigat 110 Capsule:
Taking Dabigat 110 Capsule with Defibrotide can increase the risk of bleeding leading to serious blood loss.

How to manage the interaction:
Taking Dabigat 110 Capsule with Defibrotide together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Dabigat 110 Capsule:
Using dabigatran together with dalteparin may increase the risk of bleeding.

How to manage the interaction:
Although taking Dalteparin with Dabigat 110 Capsule may possibly lead to an interaction, they can be taken if a doctor prescribes it. Consult a doctor if you have any symptoms including dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that resembles coffee grounds, severe headache, and weakness. Without consulting a doctor, never stop taking any medication.
How does the drug interact with Dabigat 110 Capsule:
Taking Dabigat 110 Capsule with Ketoprofen can increase the risk of bleeding leading to serious blood loss.

How to manage the interaction:
Taking Dabigat 110 Capsule with Ketoprofen together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Dabigat 110 Capsule:
Taking Dabigat 110 Capsule with Ticlopidine can increase the risk of bleeding leading to serious blood loss.

How to manage the interaction:
Taking Dabigat 110 Capsule with Ticlopidine together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Dabigat 110 Capsule:
Taking Dabigat 110 Capsule with Bivalirudin can increase the risk of bleeding leading to serious blood loss.

How to manage the interaction:
Taking Dabigat 110 Capsule with Bivalirudin together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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DABIGATRAN ETEXILATE-110MGHerbal products/medicines

Drug-Food Interactions

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DABIGATRAN ETEXILATE-110MGHerbal products/medicines
Common Foods to Avoid:
St. John’S Wort, Garlic Pill

How to manage the interaction:
Herbs and supplements may interact with Dabigat 110 Capsule. Avoid St. John's Wort, herbs including garlic, ginger, bilberry, danshen, piracetam, and ginkgo biloba during Dabigat 110 Capsule treatment.

Diet & Lifestyle Advise

  • Maintain healthy cholesterol and triglyceride levels.
  • Eat at regular intervals, and maintain a healthy diet that includes fresh fruits and vegetables.
  • Limit alcohol intake since it raises blood pressure and increases the risk of heart disease.
  • Monitor your weight and exercise regularly to maintain a healthy heart.

Habit Forming

No

Therapeutic Class

ANTICOAGULANT/ANTITHROMBOTIC
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Alcohol

Unsafe

You are recommended to avoid consumption of alcohol with Dabigat 110 Capsule as it may increase the risk of bleeding.

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Pregnancy

Consult your doctor

Please consult your doctor if you are planning to become pregnant or are already pregnant before starting Dabigat 110 Capsule . Your doctor will prescribe Dabigat 110 Capsule only if the benefits outweigh the risks.

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Breast Feeding

Unsafe

Avoid breastfeeding while taking Dabigat 110 Capsule . Consult your doctor if you have any concerns.

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Driving

Consult your doctor

Dabigat 110 Capsule usually does not affect your ability to drive or operate machinery. Consult your doctor if you have any concerns.

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Liver

Caution

Let your doctor know if you have/had liver diseases or hepatic impairment. Your doctor will weigh the benefits and potential risks before prescribing Dabigat 110 Capsule . However, it is not recommended for patients with severe liver diseases.

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Kidney

Caution

Let your doctor know if you have/had kidney diseases. Your doctor will weigh the benefits and potential risks before prescribing Dabigat 110 Capsule . However, it is not recommended for patients with severe kidney diseases.

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Children

Unsafe

Dabigat 110 Capsule is not recommended for children below the age of 18 years, as the safety and efficacy of Dabigat 110 Capsule have not been established in children.

FAQs

Dabigat 110 Capsule is used to prevent blood clot formation, deep vein thrombosis (blood clots in deep veins), and pulmonary embolism (blood clots in the lungs).

Dabigat 110 Capsule is a thrombin inhibitor. The inhibition of thrombin reduces the formation of blood-clotting material fibrin, thereby leading to fewer clots and aiding the free flow of blood.

Please consult your doctor if you are due to undergo surgery. The doctor might ask you to stop taking Dabigat 110 Capsule a few days before surgery since it can cause an increased risk of bleeding during surgery.

Taking Dabigat 110 Capsule during pregnancy may cause bleeding in the mother or the newborn baby. However, please consult your doctor if you are planning to become pregnant or already pregnant before starting Dabigat 110 Capsule .

Dabigat 110 Capsule may increase the risk of bleeding. It is advised to be cautious during your daily activities like shaving, cutting fingernails, or using sharp objects. Inform your doctor immediately if you notice any abnormal staining or bleeding.

No, you are not recommended to stop taking Dabigat 110 Capsule without consulting your doctor as it may worsen the condition. Therefore, take Dabigat 110 Capsule for as long as your doctor has prescribed it.

Because of the risk of bleeding, your dose of dabigatran may need to be lowered or stopped a few days before you have an operation.

You can take Dabigat 110 Capsule with or without food but try to take it at the same time every day. Swallow the capsules whole with a drink of water. Do not open dabigatran capsules before taking them, as this increases the risk of side effects.

Take Dabigat 110 Capsule as prescribed by your doctor. Depending on your medical conditions, you are advised to take Dabigat 110 Capsule as long as your doctor has prescribed it for you.

You are recommended to avoid consumption of alcohol with Dabigat 110 Capsule as it may increase the risk of bleeding.

Hair loss is not a known side effect of Dabigat 110 Capsule . However, it is known to occur with anticoagulants. Consult your doctor if you observe hair loss. Your doctor will guide you on how to cope with this situation.

It varies from person to person and depends on the conditions that we treat.

Limited research available. Let your doctor know if you have/had liver diseases or hepatic impairment. Your doctor will weigh the benefits and potential risks before prescribing Dabigat 110 Capsule . However, it is not recommended in patients with severe liver diseases.

Store in a cool and dry place away from sunlight. Keep Dabigat 110 Capsule out of the sight and reach of children.

Yes, bleeding is the main risk associated with Dabigat 110 Capsule treatment; patients should be monitored for signs of bleeding.

Dabigat 110 Capsule is not suitable for some people with existing medical conditions. So, to ensure safety, let your doctor know about all your medical conditions and medications. Your doctor will weigh the benefits and potential risks before prescribing Dabigat 110 Capsule .

Common side effects of Dabigat 110 Capsule may include bleeding, anaemia, nausea, stomach pain, and vomiting.

Country of origin

INDIA

Manufacturer/Marketer address

Natco House, Road No.2, Banjara Hills, Hyderabad-500 034, India
Other Info - DAB0380

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