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  3. Diever-250 Tablet 10's

Diever-250 Tablet 10's, Pack of 10
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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Diever-250 Tablet is used to treat epilepsy, seizures or fits. Additionally, it is also used to treat manic episodes associated with bipolar disorder and to prevent migraine. It contains Divalproex sodium, which decreases the brain's excessive and abnormal nerve activity, thereby helping to control seizures. It helps block the nerve transmission across the brain and provides a calming effect. Thereby, helps treat bipolar disorder. In some cases, it may cause common side effects, such as abdominal pain, back pain, constipation, diarrhoea, dizziness, nausea, increased appetite, and vomiting. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Composition :

DIVALPROEX SODIUM-250MG

Manufacturer/Marketer :

Everen Healthcare

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Diever-250 Tablet

Diever-250 Tablet belongs to a group of medicines called anticonvulsants or anti-epileptics used to treat epilepsy, seizures or fits. Additionally, Diever-250 Tablet is also used to treat manic episodes associated with bipolar disorder and to prevent migraine. Epilepsy is a sudden rush of electricity in the brain. In epilepsy, the brain's electrical rhythms become imbalanced, resulting in recurrent seizures.

Diever-250 Tablet contains 'Divalproex sodium', which decreases the brain's excessive and abnormal nerve activity, thereby helping in controlling seizures. Diever-250 Tablet increases the amount of a chemical substance called GABA, which helps block the nerve transmission across the brain and provides a calming effect. Thereby, it helps treat bipolar disorder. 

Take Diever-250 Tablet with or without food. You are advised to take Diever-250 Tablet as prescribed by your doctor, depending on your medical condition. In some cases, you may experience certain common side effects, such as abdominal pain, back pain, constipation, diarrhoea, dizziness, nausea, increased appetite, and vomiting. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Please do not stop taking Diever-250 Tablet without consulting your doctor to avoid worsening of seizures. Do not take Diever-250 Tablet if you are pregnant, as it could cause severe birth defects. If you are of childbearing age, use effective contraception while taking Diever-250 Tablet . Consult your doctor before taking Diever-250 Tablet if you are breastfeeding. Avoid driving or operating machinery, as Diever-250 Tablet can cause dizziness, and may affect thinking and motor skills. Avoid consuming alcohol along with Diever-250 Tablet as it could lead to increased dizziness. Care should be taken while giving Diever-250 Tablet to children below 2 years as there is a higher risk of liver intoxication during the first 6 months of treatment. Keep your doctor informed about your health condition and any medications you are taking to help rule out any potential side effects.

Uses of Diever-250 Tablet

Diever-250 Tablet is used in the treatment of seizures, bipolar disorder, and migraine. The detailed uses of Diever-250 Tablet are as follows:<br/>• Bipolar Disorder: Diever-250 Tablet treats manic episodes associated with bipolar disorder, stabilizes mood, and reduces symptoms.<br/>• Seizure Treatment: Diever-250 Tablet is used for treating complex partial seizures, absence seizures, and multiple seizure types by stabilizing electrical activity in the brain.<br/>• Migraine Prevention: Diever-250 Tablet prevents migraine headaches by reducing frequency and severity.<br/>

Directions for Use

  • Diever-250 Tablet can be taken with or without food, or as advised by the doctor.
  • It is usually taken once daily; however, your doctor may adjust the dose and frequency based on your medical condition.
  • Swallow Diever-250 Tablet as a whole with a glass of water.
  • Do not crush, chew, break, or open it.

Medicinal Benefits

Diever-250 Tablet belongs to a group of medicines called anticonvulsants or anti-epileptics. Diever-250 Tablet is used to treat epilepsy/seizures/fits. Additionally, Diever-250 Tablet is also used to treat mood disorders and to prevent migraine headaches. Diever-250 Tablet decreases the excessive and abnormal nerve activity in the brain. Thereby helps in controlling seizures. Diever-250 Tablet treats mood disorder by increasing the amount of a chemical substance called GABA, which helps block the nerve transmission across the brain and provides a calming effect. Diever-250 Tablet prevents migraine headaches by limiting the transmission of nerve pain. Diever-250 Tablet is used alone or in combination to treat simple seizures, complex partial seizures, and complex absence seizures. Diever-250 Tablet is used in combination to treat multiple seizures, such as absence seizures.

How Diever-250 Tablet Works

Diever-250 Tablet contains 'Divalproex sodium', which decreases the brain's excessive and abnormal nerve activity, thereby helping in controlling seizures. Diever-250 Tablet increases the amount of a chemical substance called GABA, which helps block the nerve transmission across the brain and provides a calming effect. Thereby, it helps treat bipolar disorder.

Storage

Keep Diever-250 Tablet out of reach and sight of children.
Side effects of Diever-250 Tablet
  • Reduce salt intake to minimize fluid buildup.
  • Use compression stockings, sleeves, or gloves.
  • Gently massage the affected area towards the heart.
  • Protect the swollen area from injury and keep it clean.
  • Use lotion or cream to keep the skin moisturized.
  • Do not stand up suddenly. Lie down and get up slowly only when you feel better.
  • Avoid alcohol and large meals.
  • Drink enough water before standing for long periods.
  • Exercise regularly; however, avoid exercising in extreme heat.
  • Eat small, low-carb meals.
  • Wear compression stockings.
Here are the steps to manage the medication-triggered Tachycardia (Fast Heart Rate):
  • Contact your doctor immediately if you're experiencing a fast heart rate, palpitations, or other heart-related symptoms. This is crucial to determine whether the symptoms are related to your medication.
  • Your doctor may need to adjust your medication regimen to alleviate the fast heart rate symptoms. This could involve changing the medication, reducing the dosage, or adding new medications to counteract the side effects.
  • Follow your doctor's advice on monitoring your heart rate and blood pressure. This will help track any changes and ensure your heart rate returns normal.
  • If you experience severe symptoms such as chest pain, dizziness, or shortness of breath, seek immediate medical attention. These symptoms can indicate a more serious condition that requires prompt treatment.
  • Regular exercise increases nitric oxide, relaxing blood vessels and improving circulation.
  • Avoid smoking and alcohol consumption as they can damage blood vessels and worsen vasodilation.
  • Foods high in omega-3 fatty acids such as walnuts, flaxseeds and fatty fish improve cardiovascular health and lower inflammation.
  • Limit the amount of salt in your regular diet.
  • Avoid triggers like alcohol, caffeine, and energy drinks.
  • Try relaxation techniques such as yoga, meditation, or deep breathing.
  • Exercise regularly as it helps maintain heart health.
  • Follow a nutritious and balanced diet.
  • Hallucination is a major psychotic disorder that needs immediate medical attention.
  • Acknowledge your experience and put effort to control hallucinations. You can share what is being seen with a therapist to know whether they are real or imaginary.
  • Avoid smoking and alcohol intake as it can worsen the condition and increase your imagination.
  • Practice meditation and yoga to avoid anxiety, which can be one of the leading causes of hallucinations.
  • Talk to your dietician and consume food that can improve your mental health.

What if I have taken an overdose of Diever-250 Tablet

Please do not take more than the prescribed dose of Diever-250 Tablet , as it may lead to an overdose. The symptoms of an overdose may include heart block, excess sleepiness, and deep coma. If you suspect you have taken an overdose or notice any of these symptoms, please consult a doctor immediately.

Drug Warnings

Do not take Diever-250 Tablet if you are allergic to any of its contents, have/had liver problems, or urea cycle disorders. Inform your doctor before taking Diever-250 Tablet if you have pancreatitis, blood problems, or multi-organ hypersensitivity. Consult your doctor immediately if you experience suicidal tendencies while taking Diever-250 Tablet . Diever-250 Tablet may cause thrombocytopenia (low blood platelets), hyperammonemia (high levels of ammonia in the blood), hypothermia (low body temperature), and liver problems. Please do not stop taking Diever-250 Tablet without consulting your doctor to avoid worsening of seizures. Do not take Diever-250 Tablet if you are pregnant, as it could cause serious birth defects. If you are of child-bearing age, use effective contraception while taking Diever-250 Tablet . Consult your doctor before taking Diever-250 Tablet if you are breastfeeding. Avoid driving or operating machinery, as Diever-250 Tablet can cause dizziness and may affect thinking and motor skills. Avoid consuming alcohol along with Diever-250 Tablet as it could lead to increased dizziness. Care should be taken while giving Diever-250 Tablet to children below 2 years as there is a higher risk of liver intoxication during the first 6 months of treatment.

Drug-Drug Interactions

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Sodium ValproateSodium phenylbutyrate
Critical
Sodium ValproateLeflunomide
Severe

Drug-Drug Interactions

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Sodium ValproateSodium phenylbutyrate
Critical
How does the drug interact with Diever-250 Tablet:
Combining Sodium phenylbutyrate and Diever-250 Tablet can increase ammonia levels in the blood.

How to manage the interaction:
Taking Sodium phenylbutyrate with Diever-250 Tablet is not recommended, but it can be taken if prescribed by a doctor. If you experience any symptoms like sudden dizziness, lightheadedness, fainting, headache, shortness of breath, nausea, vomiting, chest pain or tightness, rapid heartbeat, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateLeflunomide
Severe
How does the drug interact with Diever-250 Tablet:
Co-administration of Leflunomide and Diever-250 Tablet can increase the risk of causing liver problems.

How to manage the interaction:
Co-administration of Leflunomide and Diever-250 Tablet can lead to an interaction, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateLithium
Severe
How does the drug interact with Diever-250 Tablet:
Co-administration of Lithium with Diever-250 Tablet can increase the risk irregular heart rhythm.

How to manage the interaction:
Co-administration of Lithium and Diever-250 Tablet can lead to an interaction, but it can be taken if advised by your doctor. However, consult your doctor immediately if you experience any symptoms like dizziness, drowsiness, confusion, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, and difficulty concentrating. Do not discontinue any medications without consulting a doctor.
Sodium ValproateVorinostat
Severe
How does the drug interact with Diever-250 Tablet:
Co-administration of Vorinostat with Diever-250 Tablet can increase the risk of unusual bleeding.

How to manage the interaction:
Co-administration of Vorinostat and Diever-250 Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult your doctor immediately. Do not discontinue any medications without consulting your doctor.
Sodium ValproateErtapenem
Severe
How does the drug interact with Diever-250 Tablet:
The combined use of Ertapenem and Diever-250 Tablet can reduce the blood levels of valproic acid.

How to manage the interaction:
Co-administration of Ertapenem and Diever-250 Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like loss of seizure control or changes in behavior, consult your doctor immediately. Do not discontinue any medications without consulting the doctor.
Sodium ValproateKetamine
Severe
How does the drug interact with Diever-250 Tablet:
Co-administration of Ketamine and Diever-250 Tablet can increase side effects and cause respiratory depression.

How to manage the interaction:
Co-administration of Ketamine and Diever-250 Tablet can lead to an interaction, but it can be taken if your doctor advises. However, consult your doctor immediately if you experience any symptoms like dizziness, drowsiness, confusion, difficulty concentrating, excessive sedation, impaired thinking, judgment, and motor coordination. Avoid driving or operating hazardous machinery until you know how these medications affect you. Do not discontinue any medications without consulting the doctor.
Sodium ValproateMeropenem
Severe
How does the drug interact with Diever-250 Tablet:
Co-administration of Meropenam and Diever-250 Tablet together can reduce the effect of Diever-250 Tablet.

How to manage the interaction:
Co-administration of Meropenam and Diever-250 Tablet can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any unusual symptoms, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateTeriflunomide
Severe
How does the drug interact with Diever-250 Tablet:
Co-administration of Teriflunomide and Diever-250 Tablet can increase the risk of causing liver problems.

How to manage the interaction:
Co-administration of Teriflunomide and Diever-250 Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-colored urine, light-colored stools, and yellowing of the skin or eyes. Avoid alcohol while taking these medications, and consult your doctor immediately. Do not discontinue any medications without consulting your doctor.
Sodium ValproateBuprenorphine
Severe
How does the drug interact with Diever-250 Tablet:
Using buprenorphine together with Diever-250 Tablet may increase the risk of severe side effects, including respiratory problems and loss of consciousness.

How to manage the interaction:
Although the administration of buprenorphine alongside Diever-250 Tablet can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateDoripenem
Severe
How does the drug interact with Diever-250 Tablet:
Co-administration of Diever-250 Tablet with doripenem can reduce the blood levels of valproic acid.

How to manage the interaction:
Co-administration of Doripenam and Diever-250 Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, involuntary muscle movements, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • A ketogenic diet (low in carbohydrates and high in fats) is recommended for children with epilepsy. This diet helps in utilising fat instead of glucose for energy generation.
  • The Atkins diet (high fat and controlled carbohydrates) is recommended for adolescents and adults.
  • Exercising regularly helps maintain weight and improve overall health.
  • Rest well, get plenty of sleep.
  • Avoid smoking and alcohol consumption.
  • Meditation and yoga can help lower stress, decrease pain sensitivity, and improve coping skills.
  • Have a seizure response plan, and help those around you know what to do.
  • Prepare your living area; small changes may reduce the risk of physical injury during a seizure.
  • Understand what triggers seizures and try reducing or avoiding them.
  • Please pay attention to overall health, as it can help in reducing seizure activity.
  • Install an alarm or emergency device to get assistance during a seizure attack.

Habit Forming

No

Therapeutic Class

ANTICONVULSANT

Diever-250 Tablet Substitute

Substitutes safety advice

Product Substitutes

bannner image

Alcohol

Unsafe

Avoid consumption of alcohol while taking Diever-250 Tablet , as it may cause increased dizziness.

bannner image

Pregnancy

Unsafe

Diever-250 Tablet belongs to pregnancy category D. Avoid taking Diever-250 Tablet if you are pregnant, as it could lead to serious birth defects. Consult your doctor for further advice.

bannner image

Breast Feeding

Caution

Diever-250 Tablet may pass into breastmilk. Consult your doctor before taking Diever-250 Tablet if you are breastfeeding.

bannner image

Driving

Unsafe

Diever-250 Tablet causes dizziness and may affect thinking and motor skills. Do not drive or operate machinery until you are mentally alert.

bannner image

Liver

Unsafe

Diever-250 Tablet should not be used if you have liver problems or your family has a history of liver problems. Please consult your doctor if you have liver problems or any concerns regarding this.

bannner image

Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

bannner image

Children

Caution

Diever-250 Tablet can be given to children if prescribed by the doctor. The doctor will adjust the dose depending on the child's body weight. Care should be taken in children below 2 years as they are at a higher risk of liver toxicity.

Have a query?

FAQs

Diever-250 Tablet belongs to a group of medicines called anticonvulsants or anti-epileptics used to treat epilepsy/seizures/fits. Additionally, Diever-250 Tablet is also used to treat manic episodes associated with bipolar disorder and to prevent migraine.

Diever-250 Tablet contains 'Divalproex sodium', which decreases the brain's excessive and abnormal nerve activity, thereby helping to control seizures. Diever-250 Tablet increases the amount of a chemical substance called GABA, which helps block the nerve transmission across the brain and provides a calming effect. Thereby, it helps treat bipolar disorder.

Diever-250 Tablet helps to treat manic episodes associated with bipolar disorder by increasing the amount of a chemical substance called GABA, which helps in blocking the nerve transmission across the brain and provides a calming effect.

Diever-250 Tablet limits the transmission of nerve pain, thereby preventing migraine headaches. Migraine is a neurological condition characterised by intense headaches.

Do not discontinue Diever-250 Tablet without consulting your doctor. To treat your condition effectively, continue taking Diever-250 Tablet for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Diever-250 Tablet , your doctor will reduce the dose gradually to avoid worsening of seizures.

Diever-250 Tablet may cause weight gain due to an increase in appetite. Maintain a healthy weight by following a healthy diet and exercising regularly.

Use an effective method of contraception during the treatment with Diever-250 Tablet . Avoid getting pregnant while taking Diever-250 Tablet as it could lead to serious birth defects. Do not stop taking Diever-250 Tablet and consult your doctor immediately if you become pregnant.

Diever-250 Tablet may cause thrombocytopenia (low levels of platelets). This might increase the risk of bleeding and bruising. Be cautious while using sharp objects. Consult your doctor if you notice unexplained bleeding or bruising. Regular monitoring of blood count is advised while taking Diever-250 Tablet .

Topiramate (anticonvulsant) should not be taken along with Diever-250 Tablet as it may cause hyperammonemia (excess ammonia in the blood), hypothermia (low body temperature) and liver problems.

It is crucial to consult with your doctor before discontinuing Diever-250 Tablet . Abruptly stopping this medication can lead to severe consequences, mainly if it's prescribed to treat conditions like epilepsy.

Diever-250 Tablet is also used to treat mood disorders. It treats mood disorders by increasing the amount of a chemical substance called GABA, which helps block nerve transmission across the brain and provides a calming effect.

Diever-250 Tablet can indeed make you sleepy. This is a common side effect of the medication. If you're experiencing excessive drowsiness, please consult your doctor.

Yes, Diever-250 Tablet can cause hair loss as a side effect. While this isn't a common side effect, it can occur in some people. If you notice significant hair loss while taking Diever-250 Tablet , it's essential to consult with your doctor.

Yes, Diever-250 Tablet can potentially damage your liver. While this is a rare side effect, being aware of the risk is essential. Signs of liver damage may include yellowing of the skin or eyes or jaundice, dark urine, abdominal pain, light-coloured stools, nausea and vomiting. If you experience any of these symptoms while taking Diever-250 Tablet , seeking medical attention is crucial.

Avoid consumption of alcohol while taking Diever-250 Tablet , as it may cause increased dizziness.

If you experience abdominal pain, nausea, and anorexia while taking Diever-250 Tablet , it's essential to contact your doctor immediately. These symptoms can be signs of a severe side effect, such as liver damage.

An overdose of Diever-250 Tablet can be a severe medical emergency. The symptoms of an overdose may include heart block, excess sleepiness, and deep coma. If you or someone you know has taken an overdose of Diever-250 Tablet , please seek immediate medical attention.

Country of origin

India

Manufacturer/Marketer address

Plot no-39, Niranjan Vihar-1 , Sirsi Road, Near Bindayaka Industrial Area Phase-1 P.O-Bindayaka, Jaipur (Rajasthan), Pin Code-302012
Other Info - DIE0046

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Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 6:43 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/018723s037lbl.pdf
  2. https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=e26005ef-77f0-4393-a2dc-b5fe460cead8&amp;type=display
  3. https://www.drugs.com/mtm/divalproex-sodium.html
  4. https://www.depakote.com/depakote-formulations

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