apollo
0

Welcome User

Login/Sign Up

Home
Buy Medicines
Lab Tests
Doctor Consult
Circle Membership
insurance
Blogs
Contact Us
Privacy Policy
Return & Refunds
Need Help
Terms and Conditions
  1. Home
  2. Medicine

  3. Hitoral 200mg Tablet

Hitoral 200mg Tablet, Pack of 1 Tablet
Thumbnail 0
Written By Veda Maddala , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
Hitoral 200mg Tablet is an antifungal medicine used in the treatment of fungal infections such as blastomycosis, coccidioidomycosis, paracoccidioidomycosis, and histoplasmosis (lung infection caused by Histoplasma fungus). This medicine works by inhibiting the growth and multiplication of fungal cells that are responsible for the growth of infection-causing fungi.
Read more

Available Offers

Coupon IconPHARMA18
18% OFF, applicable on orders > INR 2999
Coupon IconPHARMA10
10% OFF, applicable on orders > INR 799
Coupon IconPHARMA20
20% OFF, applicable on orders > INR 5499
rxMedicinePrescription drug

Whats That

tooltip

Extra Savings

Momverse
insurance
doctor consultation

Composition :

KETOCONAZOLE-200MG

Manufacturer/Marketer :

Synmedic Laboratories

Consume Type :

ORAL

Return Policy :

Not Returnable

About Hitoral 200mg Tablet

Hitoral 200mg Tablet belongs to a class of drugs called antifungals indicated to treat various systemic fungal infections such as blastomycosis (infection caused by Blastomyces fungus), chromomycosis (chronic infection of the skin and subcutaneous tissue), Coccidioidomycosis (infection caused by Coccidioides fungus), paracoccidioidomycosis (infection caused by Paracoccidioides fungus) and histoplasmosis (lung infection caused by Histoplasma fungus). It is used only when other effective antifungal therapies are not available or tolerated and if potential benefits outweigh potential risks.

Hitoral 200mg Tablet contains Ketoconazole which works by destroying fungal cell membranes that are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Thus, kills fungi and treats the fungal infection.

Take Hitoral 200mg Tablet as prescribed. Your doctor will advise you on how often you need to take Hitoral 200mg Tablet based on your medical condition. Some people may experience headache, nausea, stomach pain, and diarrhoea. Most of these side effects of Hitoral 200mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. 

If you are allergic to Ketoconazole or any other medicines, please tell your doctor. If you are pregnant or planning for pregnancy, inform your doctor before taking Hitoral 200mg Tablet. Avoid breastfeeding while taking Hitoral 200mg Tablet as it may be excreted in breast milk. You are recommended to avoid alcohol consumption whilst on treatment with Hitoral 200mg Tablet. Hitoral 200mg Tablet is not recommended for children below 2 years of age. For children above 2 years, it is recommended to use only if the doctor has determined that the benefits outweigh the risks.

Uses of Hitoral 200mg Tablet

Treatment of Systemic fungal infections

Directions for Use

Take Hitoral 200mg Tablet with food to avoid stomach upset or take it as advised by the doctor. Swallow the whole tablet/capsule with a glass of water. Do not break, crush or chew it.

Medicinal Benefits

Hitoral 200mg Tablet is an antifungal used to treat severe fungal infections. It is used only when other effective antifungal therapies are not available or tolerated and if potential benefits outweigh potential risks. It destroys fungal cell membranes that are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Thus, kills fungi and treats the fungal infection.

How Hitoral 200mg Tablet Works

Hitoral 200mg Tablet contains Ketoconazole which works by destroying fungal cell membranes that are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Thus, kills fungi and treats the fungal infection.

Storage

Store in a cool and dry place away from sunlight
Side effects of Hitoral 200mg Tablet
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

What if I have taken an overdose of Hitoral 200mg Tablet

Never take more than the prescribed dose. When Hitoral 200mg Tablet is used at high doses, it may, though unlikely, result in decreased testosterone levels, sperm production, and an issue with the adrenal glands (adrenal insufficiency). Seek emergency medical help if an overdose is suspected.

Drug Warnings

If you are allergic to Ketoconazole or any other medicines, please tell your doctor. If you are pregnant or planning for pregnancy, inform your doctor before taking Hitoral 200mg Tablet. Avoid breastfeeding while taking Hitoral 200mg Tablet as it may be excreted in breast milk. You are recommended to avoid alcohol consumption with Hitoral 200mg Tablet. If you have a loss of appetite, tiredness, stomach pain, vomiting, yellowing of skin or eyes, dark urine, or light-coloured stools, inform your doctor immediately as they might be symptoms of hepatotoxicity (liver damage). 

Drug-Drug Interactions

verifiedApollotooltip
KetoconazoleVenetoclax
Critical
KetoconazoleTolvaptan
Critical

Drug-Drug Interactions

Login/Sign Up

KetoconazoleVenetoclax
Critical
How does the drug interact with Hitoral 200mg Tablet:
When Venetoclax is taken with Hitoral 200mg Tablet, it can increase the risk of side effects.

How to manage the interaction:
Taking Hitoral 200mg Tablet with Venetoclax is not recommended as it can cause an interaction, but it can be taken if prescribed by the doctor. if you experience nausea, vomiting, diarrhea, fatigue, bleeding problems, and infections, consult a doctor. Do not stop using any medications without talking to a doctor.
KetoconazoleTolvaptan
Critical
How does the drug interact with Hitoral 200mg Tablet:
When Tolvaptan is taken with Hitoral 200mg Tablet, may increase the risk of side effects.

How to manage the interaction:
Taking Tolvaptan with Hitoral 200mg Tablet is not recommended as it can lead to an interaction, it can be taken if prescribed by a doctor. However, if you notice any of these signs -difficulty swallowing, trouble speaking, muscle weakness, trouble controlling body movements, confusion, mood changes, seizures, call a doctor right away. Do not stop using any medications without a doctor's advice.
KetoconazoleNisoldipine
Critical
How does the drug interact with Hitoral 200mg Tablet:
When Nisoldipine is taken with Hitoral 200mg Tablet, it can increase the blood levels of Nimodipine which may lead to serious side effects (irregular heart rhythm, fluid retention, swelling, and extremely low blood pressure).

How to manage the interaction:
Taking Hitoral 200mg Tablet with Nisoldipine can cause an interaction, but it can be taken if prescribed by the doctor. However, if you experience irregular heart rhythm, fluid retention, swelling, and extremely low blood pressure while using these medications, consult the doctor. Do not stop using any medications without talking to a doctor.
KetoconazoleLurasidone
Critical
How does the drug interact with Hitoral 200mg Tablet:
Using Lurasidone together with Hitoral 200mg Tablet may increase the risk of side effects like Parkinson's disease(It is a brain disorder that produces uncontrollable movements).

How to manage the interaction:
While lurasidone and Hitoral 200mg Tablet is not recommended as it may lead to an interaction, they can be used if prescribed by a doctor. However, consult a doctor if you have any abnormal muscle activity, fits, heat intolerance or heat stroke, dizziness, lightheadedness, headache, flushing, fainting, or heart palpitations. Do not discontinue any medications without consulting a doctor.
KetoconazoleHalofantrine
Critical
How does the drug interact with Hitoral 200mg Tablet:
Using Hitoral 200mg Tablet with Halofantrine can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Hitoral 200mg Tablet with Halofantrine is not recommended as it can cause an interaction, it can be taken if prescribed by the doctor. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.
KetoconazoleLovastatin
Critical
How does the drug interact with Hitoral 200mg Tablet:
Coadministration of Lovastatin with Hitoral 200mg Tablet can increase the risk of liver damage, rhabdomyolysis (the breakdown of skeletal muscle tissue) which may lead to kidney damage.

How to manage the interaction:
Taking Hitoral 200mg Tablet with Lovastatin is not recommended as it can cause an interaction, it can be taken if a doctor has advised it. However, if you experience symptoms like unexplained muscular pain, tenderness, weakness, accompanied by fever, dark urine or unexpected bruising or bleeding, skin rash, itching, vomiting, yellowing of the skin or eyes, chills, joint pain, swelling, consult a doctor immediately. Do not discontinue any medication without consulting a doctor.
KetoconazoleIvabradine
Critical
How does the drug interact with Hitoral 200mg Tablet:
Coadministration of Ivabradine with Hitoral 200mg Tablet can increase the risk or severity of side effects.

How to manage the interaction:
Taking Ivabradine with Hitoral 200mg Tablet is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
KetoconazoleDofetilide
Critical
How does the drug interact with Hitoral 200mg Tablet:
When Dofetilide is taken with Hitoral 200mg Tablet, it can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Hitoral 200mg Tablet with Dofetilide is not recommended as it can cause an interaction, it can be taken if prescribed by the doctor. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.
KetoconazoleConivaptan
Critical
How does the drug interact with Hitoral 200mg Tablet:
Using conivaptan together with Hitoral 200mg Tablet may significantly increase the blood levels of conivaptan, which may increase the risk of side effects.

How to manage the interaction:
Taking Hitoral 200mg Tablet with Conivaptan is not recommended as it can cause an interaction, but it can be taken if prescribed by the doctor. However, if you experience difficulty swallowing, trouble speaking, muscle weakness, trouble controlling body movements, confusion, mood changes, seizures(fits), consult the doctor immediately. Do not discontinue any medication without consulting a doctor.
KetoconazoleMethadone
Critical
How does the drug interact with Hitoral 200mg Tablet:
When Methadone is taken with Hitoral 200mg Tablet, it can increase the risk of serious side effects such as respiratory problems, low blood pressure, irregular heart rhythm.

How to manage the interaction:
Taking Hitoral 200mg Tablet with Methadone is not recommended as it can cause an interaction, it can be taken if prescribed by the doctor. However, if you experience breathing difficulty, fainting, heart palpitations, consult the doctor immediately. Do not discontinue any medication without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
KETOCONAZOLE-200MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

Login/Sign Up

KETOCONAZOLE-200MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Consumption of grapefruit or its juice with Hitoral 200mg Tablet may result in side effects such as joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of hunger, dark urine, light colored stools, and yellowing of the skin or eyes. Avoid consuming grapefruit, grapefruit juice, or any supplements that include grapefruit extract while taking Hitoral 200mg Tablet.

Diet & Lifestyle Advise

  • Avoid high-risk areas such as renovated buildings, construction sites, pigeon or chick coops, and caves.
  • Wear a respiratory mask when there is a risk of exposure to spores.
  • People with a weak immune system are advised to avoid activities that involve close contact with dust or dirt including digging, yard work, and gardening.
  • Close windows and stay inside during dust storms.
  • Clean skin injuries well with soap and water to reduce the risk of developing a skin infection.

Habit Forming

No

Therapeutic Class

ANTIFUNGALS - ORAL

Hitoral 200mg Tablet Substitute

Substitutes safety advice

  • Fungicide Tablet 10's

    by Others

    ₹47.52per tablet

  • Phytoral Tablet 10's

    by Others

    ₹46.08per tablet

  • Kenz Tablet 10's

    by AYUR

    ₹21.60per tablet

  • Hyphoral Tablet 10's

    by Others

    ₹38.03per tablet

  • Ketocip 200 mg Tablet 10's

    by Others

    ₹21.78per tablet

Product Substitutes

bannner image

Alcohol

Unsafe

Avoid consumption of alcohol while taking Hitoral 200mg Tablet as it may increase the risk of liver damage and cause adverse effects.

bannner image

Pregnancy

Caution

Hitoral 200mg Tablet is a Category C pregnancy drug and is given to pregnant women only if the doctor thinks the benefits outweigh the risks.

bannner image

Breast Feeding

Unsafe

Hitoral 200mg Tablet may be excreted in breast milk. Therefore, it is recommended to avoid breastfeeding while taking Hitoral 200mg Tablet.

bannner image

Driving

Caution

Hitoral 200mg Tablet may cause dizziness or drowsiness. Therefore, drive only if you alert after taking Hitoral 200mg Tablet.

bannner image

Liver

Unsafe

Hitoral 200mg Tablet is contraindicated in patients with chronic or acute liver disease. Therefore, inform your doctor if you have any Liver diseases/conditions.

bannner image

Kidney

Caution

If you have any concerns regarding the use of Hitoral 200mg Tablet in patients with kiver diseases/conditions, consult a doctor.

bannner image

Children

Caution

Hitoral 200mg Tablet is not recommended for children below 2 years of age. For children above 2 years, it is recommended to use only if the doctor has determined that benefits outweigh risks.

FAQs

Hitoral 200mg Tablet belongs to a class of drugs called antifungals indicated to treat various systemic fungal infections such as blastomycosis (infection caused by Blastomyces fungus), chromomycosis (chronic infection of the skin and subcutaneous tissue), Coccidioidomycosis (infection caused by Coccidioides fungus), paracoccidioidomycosis (infection caused by Paracoccidioides fungus) and histoplasmosis (lung infection caused by Histoplasma fungus).

Hitoral 200mg Tablet works by destroying fungal cell membranes that are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Thus, kills fungi and treats the fungal infection.

Hitoral 200mg Tablet is not recommended to treat fungal meningitis (fungal infection spreads to the brain and spinal cord) as it poorly penetrates into the cerebrospinal fluid. Therefore, inform your doctor if you have fungal meningitis so that appropriate medication may be prescribed.

You are recommended to avoid foods containing chocolate and caffeine such as cocoa beans, tea, coffee, cola and energy drinks while taking Hitoral 200mg Tablet as it may increase the adverse effects of caffeine such as drowsiness, nervousness or nausea.

You are not recommended to take Hitoral 200mg Tablet with simvastatin (lipid-lowering drug) as co-administration of these medicines may cause muscle problems. Therefore, please consult a doctor before taking Hitoral 200mg Tablet with other medicines.

No, you are not recommended to stop taking Hitoral 200mg Tablet without consulting your doctor as it may cause recurring infection. Therefore, take Hitoral 200mg Tablet for as long as your doctor has prescribed it and if you experience any difficulty while taking Hitoral 200mg Tablet, please consult your doctor.

Country of origin

India
Other Info - HI90768

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Author Details

Doctor imageDoctor badge

Written By

Veda Maddala

M Pharmacy

Doctor imageDoctor badge

Reviewed By

Santoshini Reddy G

M Pharmacy

Last Updated

Jan 1, 2025 | 2:45 PM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.accessdata.fda.gov/drugsatfda_docs/label/2013/018533s040lbl.pdf
  2. https://www.drugs.com/mtm/ketoconazole.html
whatsapp Floating Button