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Hynidase 1500IU Injection is used to improve the absorption of injections. It contains Hyaluronidase which works by increasing the permeability of connective tissue through hyaluronic acid hydrolysis. In some cases, this medicine may cause side effects such as swelling, irritation, or bruising at the injection site. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Manufacturer/Marketer :

Shreya Life Sciences Pvt Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Hynidase 1500IU Injection

Hynidase 1500IU Injection is a specialised injection used to help your body absorb injected fluids, local anaesthetics, and other medications more quickly and efficiently. It is also commonly used to help absorb fluids given under the skin for hydration, a method called hypodermoclysis. This medicine temporarily helps injected fluids and compatible medicines spread more easily through body tissues.

Because Hynidase 1500IU Injection is an injection, it is typically given on an as-needed basis by a healthcare professional rather than on a daily, routine schedule. Since it is injected directly into the tissue, it does not matter if you have eaten recently, as food does not affect how this medication works in your body. Drinking plenty of water and resting the treated area after your injection can help support your body's natural recovery process.

Most patients tolerate this treatment well, but it can cause mild, localised side effects such as redness, swelling, or warm feelings at the injection site. If you experience severe reactions like spreading redness, extreme swelling, or hives, you must consult your doctor immediately. These symptoms could indicate an allergic response or an infection that requires prompt medical attention.

Before receiving this medication, you must talk to your doctor if you have any history of severe allergies, active skin infections, or cancer in the area where the injection is planned. Do not receive Hynidase 1500IU Injection if you have a known allergy to animal proteins (as some formulations are derived from animal sources) or if the target area is actively infected, inflamed, or swollen due to an insect bite.

Certain medications, including antihistamines, corticosteroids, and estrogens, can interact with Hynidase 1500IU Injection and reduce its overall effectiveness. If you are pregnant, planning to become pregnant, breastfeeding, or are an elderly patient, you must consult your healthcare provider to discuss whether this treatment is appropriate for you.

Uses of Hynidase 1500IU Injection

Hynidase 1500IU Injection is used as an adjunct to improve the spread and absorption of injected fluids and certain compatible medicines during specific medical procedures. Its uses include:

  • Enhancing Drug Absorption: Hynidase 1500IU Injection helps certain injected medicines, such as local anaesthetics, spread more easily through tissues.
  • Subcutaneous Hydration: It helps fluids given under the skin absorb more effectively when intravenous access is difficult or unsuitable.
  • Subcutaneous Urography (an imaging test using dye injected under the skin): Hynidase 1500IU Injection may be used to help the dye absorb more effectively so X-ray images of the kidneys and urinary tract can be taken.
  • Ophthalmic Procedures: It may be added to local anaesthetic injections used around the eye during certain eye surgeries to help the anaesthetic spread more effectively through surrounding tissues.

Key Benefits

Hynidase 1500IU Injection temporarily makes body tissues easier for injected fluids and compatible medicines to move through, helping them spread and absorb more effectively during selected medical procedures.

  • Improves Absorption of Injected Fluids: Helps fluids given under the skin spread through tissues and absorb more efficiently.
  • Enhances Dispersion of Certain Medicines: Helps compatible injected medicines, including some local anaesthetics, spread more effectively when used under medical supervision.
  • Supports Subcutaneous Fluid Administration: Facilitates fluid absorption when intravenous access is difficult or unsuitable.
  • Reduces Localised Fluid Pooling: Improved fluid dispersion may help reduce pressure and discomfort caused by fluid collecting in one area.
  • Supports Certain Medical Procedures: Helps injected fluids and compatible medicines move more easily through tissues during selected diagnostic and treatment procedures.

Directions for Use

  • Follow your doctor’s instructions on the dosage and timing of this medication.
  • Hynidase 1500IU Injection will be administered by the doctor or nurse in a healthcare setting.
  • Do not self-administer.

How Hynidase 1500IU Injection Works

Hynidase 1500IU Injection works by temporarily loosening the natural substance that helps hold body tissues together, allowing injected fluids and compatible medicines to spread more easily. It contains hyaluronidase, an enzyme that temporarily breaks down hyaluronic acid, a natural substance found between cells in the body's tissues. Hyaluronic acid helps maintain tissue structure and limits how freely fluids move through these spaces. By breaking down some of this hyaluronic acid, Hynidase 1500IU Injection temporarily makes the tissue less resistant to fluid movement. This allows injected fluids and compatible medicines to spread more easily between cells and absorb more efficiently into surrounding tissues or the bloodstream. The effect is temporary, and the body gradually restores its normal tissue structure after treatment.
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Alcohol

Caution

It is unknown if alcohol interacts with Hynidase 1500IU Injection. Please consult your doctor before consuming alcohol, along with Hynidase 1500IU Injection.

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Pregnancy

Caution

Hynidase 1500IU Injection is pregnancy category C drug. It can only be injected in pregnant women if suggested by the doctor as the safety and effectiveness of Hynidase 1500IU Injection has not been established.

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Breast Feeding

Caution

Hynidase 1500IU Injection can only be injected in breastfeeding women when suggested by the doctor as safety and effectiveness of Hynidase 1500IU Injection has not been established.

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Driving

Caution

In some cases, Hynidase 1500IU Injection may cause dizziness and drowsiness. So if you observe such symptoms, immediately consult your doctor.

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Liver

Caution

Hynidase 1500IU Injection can only be injected in persons dealing with liver disease if prescribed by a doctor.

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Kidney

Caution

Hynidase 1500IU Injection can only be injected in persons dealing with kidney disease if prescribed by a doctor.

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Children

Caution

Hynidase 1500IU Injection can be used in children only when prescribed by a doctor.

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Heart

Consult your doctor

Please inform your doctor if you have a history of heart disease before using Hynidase 1500IU Injection. Your doctor will prescribe it only if the benefits outweigh the risks.

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Geriatrics

Consult your doctor

Limited information available for use of Hynidase 1500IU Injection in elderly patients. Please consult your doctor.

What if I have taken an overdose of Hynidase 1500IU Injection

Because Hynidase 1500IU Injection is administered by healthcare professionals, an overdose is rare. However, if too much medication is injected, you may experience increased local redness, swelling, or a rapid heartbeat. In the event of a suspected overdose, seek immediate medical attention or contact an emergency poison control centre.

Diet & Lifestyle Advise

  • Stay well-hydrated: Drink plenty of water before and after your treatment to support your body's fluid balance and enhance the absorption of the injected fluids.
  • Rest the injection site: Avoid heavy lifting, vigorous exercise, or putting excessive pressure on the treated area for at least 24 hours after the injection.
  • Do not massage the area: Unless specifically instructed by your healthcare provider, avoid rubbing or massaging the injection site, as this can affect how the medication spreads.
  • Monitor your skin: Keep a close eye on the skin around the injection site for any unusual changes, such as worsening redness, warmth, or pus, which could indicate a complication.
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How Soon It Starts Working

The time required for Hynidase 1500IU Injection to start to work: The time required for Hynidase 1500IU Injection to show its action is unknown. The time for which the effects of Hynidase 1500IU Injection last: The duration of action for Hynidase 1500IU Injection is clinically unknown.

What if you forget to take Hynidase 1500IU Injection

Since this medication is usually given in a clinical setting by a healthcare professional immediately before or during a procedure, missing a dose is highly unlikely. If you are on a specific outpatient treatment plan and miss an appointment, contact your doctor or clinic right away to reschedule.

Storage

• If you are storing Hynidase 1500IU Injection at home under medical supervision, keep the vials in their original packaging to protect them from light.

Drug Warnings

  • Inspect the Solution Before Use: The solution should be clear and free from visible particles. Do not use it if it appears cloudy, discoloured, or contains particles.
  • Avoid Infected or Cancerous Areas: Hynidase 1500IU Injection should not be injected into or around these areas because it may help infection or cancer cells spread into nearby tissues.
  • Report Any History of Allergies: Tell your healthcare provider about previous severe allergic reactions before receiving Hynidase 1500IU Injection. Appropriate allergy assessment may be considered when clinically indicated.
  • Ensure Safe Needle Disposal: Used needles and syringes should be discarded immediately in an approved puncture-resistant sharps container and must never be reused.

Drug-Drug Interactions

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Certain medicines may interact with Hynidase 1500IU Injection and alter its effectiveness or affect the absorption and duration of other injected medicines. Important interactions include:

  • Local Anaesthetics: When mixed with local anaesthetics, Hynidase 1500IU Injection can cause the numbing effect to wear off more quickly because the anaesthetic is absorbed faster into your system.
  • Antihistamines, Corticosteroids, and Oestrogens: Taking these medications may make your tissues more resistant to Hynidase 1500IU Injection, meaning a higher dose may be required to achieve the desired fluid-spreading effect.
  • Salicylates (such as aspirin): These medications can also reduce the chemical effectiveness of Hynidase 1500IU Injection in the body.
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

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  • Food: No specific food interactions are generally expected because Hynidase 1500IU Injection is given by injection.
  • Fluid Intake: Follow your healthcare provider’s advice about hydration. Do not increase fluid intake beyond medical advice, particularly if you have heart or kidney problems.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[MISCELLANEOUS]

FAQs

Hynidase 1500IU Injection is used together with fluids injected into the body to treat dehydration. It is also used to aid in the absorption of injections and enable excess fluids and blood in the tissues to be more easily re-absorbed. Besides this, it is also used to help contrast dyes in the body show more clearly on certain types of X-rays or scans.
Hynidase 1500IU Injection contains Hyaluronidase, an enzyme that increases the permeability of connective tissue through the hydrolysis of hyaluronic acid and increases the diffusion of injected fluids or localized transudates exudates, thus facilitating their absorption.
Do not try to take injections on your own. Hynidase 1500IU Injection has to be given by the registered medical practitioner (RMP) or doctor.
Yes, Hynidase 1500IU Injection can cause dizziness in some patients. So, drive only if you are alert and omit driving or operating machinery if you feel dizzy or drowsy.
The common side-effects of Hynidase 1500IU Injection are allergic reaction, hormone imbalance, slow growth in children and teenagers, angioedema (swelling of deeper layers of skin), dizziness, injection site reaction, and oedema (swelling).
A person of age 65 or older should use Hynidase 1500IU Injection with caution, as directed by the doctor, as the chances of side effects increase in older people.
It is used as an injection to help your body absorb fluids, local anaesthetics, and other injected medications more quickly and efficiently. Talk to your doctor to learn more about why it was prescribed for you.
No, Hynidase 1500IU Injection is not designed for direct intravenous injection; it is typically injected under the skin or into the muscle to help disperse fluids in those tissues. Talk to your doctor if you have concerns about the administration route.
It should only be used during pregnancy if clearly needed and prescribed by your doctor, as there is limited data on its effects on unborn babies. Talk to your doctor to weigh the benefits and risks.
A skin test may be performed to check if you are allergic to the medication, especially since some formulations are derived from animal sources. Talk to your doctor if you have a history of severe allergies.
While it helps disperse fluids, it is not a direct treatment for general swelling and should never be injected into areas swollen from infections or insect bites. Talk to your doctor about the appropriate treatment for your swelling.
This could be a sign of a localised infection or a severe allergic reaction. You should contact your healthcare provider or seek medical attention immediately. Talk to your doctor if you notice any unusual skin changes.
Yes, it can interact with drugs like antihistamines, corticosteroids, estrogens, and certain pain relievers, which may make Hynidase 1500IU Injection less effective. Talk to your doctor or pharmacist about all the medications you currently take.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

INDIA

Manufacturer/Marketer address

SHREYA HOUSE, 301/A, Pereira Hill Road, Andheri East, Mumbai - 400 099, India
Other Info - HYN0001
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