Buy Lupiclor 12.5 mg Tablet online | Uses, Side Effects, Price and substitutes

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Composition:CHLORTHALIDONE-12.5MG

Prescription Medicine

Lupiclor 12.5 mg Tablet is used to treat high blood pressure, heart failure and oedema (a build-up of fluid in the body). It contains Chlorthalidone, which works by increasing the amount of urine that is passed out from the kidneys. Thereby, it helps treat hypertension and oedema. In some cases, you may experience headaches, nausea or dizziness, which usually resolve over time. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

Written By Bayyarapu Mahesh Kumar , M Pharmacy

Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

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More about the Product

Composition :

CHLORTHALIDONE-12.5MG

Manufacturer/Marketer :

Lupin Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Lupiclor 12.5 mg Tablet

Lupiclor 12.5 mg Tablet is a prescription medicine used to treat high blood pressure and reduce swelling caused by excess fluid in your body. By helping your kidneys remove extra salt and water, this medication decreases the workload on your heart and blood vessels. Using it consistently helps protect your long-term health by reducing the risk of strokes and heart attacks.

For the best results, you should take Lupiclor 12.5 mg Tablet at the same time every day, preferably in the morning to prevent having to wake up during the night to urinate. You can take this medicine with or without food, but maintaining a consistent routine is important for steady blood pressure control. Combining this treatment with a low-salt diet and regular, doctor-approved exercise will help you achieve the best possible results.

While taking this medicine, you may experience mild side effects like an increased need to urinate, mild dizziness, or a temporary headache. These symptoms are usually manageable, but you must contact your doctor immediately if you experience serious side effects such as severe muscle cramps, extreme thirst, or an irregular heartbeat.

Before you begin taking Lupiclor 12.5 mg Tablet , talk to your doctor if you have a history of kidney disease, liver damage, diabetes, gout, or low potassium levels. Do not take this if you are unable to pass urine or if you have a known severe allergy to sulfonamide medications.

Certain medicines, including regular pain relievers and other blood pressure drugs, can interact with Lupiclor 12.5 mg Tablet and affect how it works. Drinking alcohol while taking this medicine can cause your blood pressure to drop too low, leading to severe dizziness. If you are pregnant, breastfeeding, or an elderly individual, consult your doctor or pharmacist before starting this treatment to ensure it is safe for you.

Uses of Lupiclor 12.5 mg Tablet

Lupiclor 12.5 mg Tablet contains chlorthalidone and is used to lower blood pressure and reduce excess fluid accumulation in the body. The detailed uses of Lupiclor 12.5 mg Tablet are as follows:

High Blood Pressure (Hypertension): Lupiclor 12.5 mg Tablet helps lower elevated blood pressure, which reduces the workload on your heart and protects your blood vessels from long-term damage.
Fluid Retention (Oedema): Lupiclor 12.5 mg Tablet helps your body eliminate excess water and salt caused by conditions like heart failure, kidney disease, or liver disease, reducing swelling in your limbs.

Key Benefits

Lupiclor 12.5 mg Tablet helps control blood pressure and reduce excess fluid in the body, supporting cardiovascular health and improving physical comfort. Regular treatment helps protect against the complications associated with uncontrolled high blood pressure.

Long-Lasting Blood Pressure Control: Lupiclor 12.5 mg Tablet provides sustained blood pressure control throughout the day and night, helping reduce the risk of serious cardiovascular events such as strokes and heart attacks.
Relief from Swelling and Fluid Retention: By helping remove excess fluid from the body, Lupiclor 12.5 mg Tablet reduces swelling in the legs, ankles, and feet, making walking, movement, and other daily activities more comfortable.

Side effects of Lupiclor 12.5 Tablet

High Uric Acid Levels In Blood

Low Potassium Levels In Blood

Talk to your doctor about oral potassium supplements.
Eat potassium rich foods such as bananas, avocados, oranges, dark leafy greens, beans and peas, fish, spinach, milk and tomatoes.

High Levels Of Fat In Blood

Limit intake of full-fat dairy products, red meat and processed foods rich in saturated fats.
Avoid foods with label “partially hydrogenated oils”.
Eat more vegetables, fruits, oats, whole grains, lentils and beans to increase fiber intake.
Include foods rich in monounsaturated fats like nuts, avocados, olive oil, and oily fish.
Limit consumption of egg yolks.
Exercise for at least 30 minutes 5 days a week.
Aim for weight loss and maintain healthy weight.
Quit smoking as smoking raises the risk of heart disease associated with cholesterol.
Limit alcohol consumption as excessive drinking may raise cholesterol levels.

Low Blood Pressure

Managing Low Blood Pressure Triggered by Medication: Expert Advice:

If you experience low blood pressure symptoms like dizziness, lightheadedness, or fainting while taking medication, seek immediate medical attention.
Make lifestyle modifications and adjust your medication regimen under medical guidance to manage low blood pressure.
As your doctor advises, regularly check your blood pressure at home. Record your readings to detect any changes and share them with your doctor.
Fluid intake plays a vital role in managing blood pressure by maintaining blood volume, regulating blood pressure, and supporting blood vessel function. Drinking enough fluids helps prevent dehydration, maintain electrolyte balance, and regulate fluid balance.
Take regular breaks to sit or lie down if you need to stand for long periods.
When lying down, elevate your head with extra pillows to help improve blood flow.
Avoid heavy exercise or strenuous activities that can worsen low blood pressure.
Wear compression socks as your doctor advises to enhance blood flow, reduce oedema, and control blood pressure.
If symptoms persist or worsen, or if you have concerns about your condition, seek medical attention for personalized guidance and care.

Erectile Dysfunction

Quit smoking as smoking impairs erectile function by significantly damaging blood vessels.
Maintain a healthy weight as overweight can cause erectile dysfunction.
Exercise regularly as physical activity enhances blood flow and overall health, benefiting erectile function.
Consume a healthy diet loaded with whole grains, fruits and vegetables.
Limit alcohol consumption as excessive alcohol intake can impair erectile function.
Manage stress by practicing techniques such as yoga, relaxation exercises or meditation.
In case erectile dysfunction is due to psychological factors, consider couple counselling or sex therapy to address relationship and anxiety issues.
Openly discuss your concerns with your partner.

Dizziness

Here are the 7 steps to manage Dizziness caused by medication:

Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
When standing up, do so slowly and carefully to avoid sudden dizziness.
Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.

Drop In Blood Pressure Upon Standing Up

Do not stand up suddenly. Lie down and get up slowly only when you feel better.
Avoid alcohol and large meals.
Drink enough water before standing for long periods.
Exercise regularly; however, avoid exercising in extreme heat.
Eat small, low-carb meals.
Wear compression stockings.

Directions for Use

Follow these step-by-step instructions to take your medicine safely:

Swallow the tablet whole with a full glass of water. Do not crush, chew, or break the tablet.
Take this medicine in the morning to prevent nighttime sleep disruptions from needing to urinate.
You can take your dose with or without food, but try to do it the same way every day.

Always follow your doctor's exact instructions regarding your treatment. Do not stop taking this medication suddenly, even if you feel completely well.

How Lupiclor 12.5 mg Tablet Works

Lupiclor 12.5 mg Tablet contains chlorthalidone, which belongs to a group of medicines known as diuretics, commonly called 'water pills.' It acts directly on the filtering units of your kidneys to increase the amount of sodium and water that your body removes from your bloodstream and excretes through your urine. As your body sheds this extra salt and water, the total volume of blood circulating through your blood vessels goes down. This reduction in fluid volume lowers the pressure against your artery walls and decreases the strain on your heart, allowing it to pump blood more easily throughout your body.

Alcohol

Unsafe

You are recommended not to consume alcohol along with Lupiclor 12.5 mg Tablet to avoid unpleasant side-effects.

Pregnancy

Unsafe

Lupiclor 12.5 mg Tablet is classified as FDA pregnancy risk category B. So, Lupiclor 12.5 mg Tablet should not be used during pregnancy unless clearly necessary. Prolonged intake of Lupiclor 12.5 mg Tablet during pregnancy may cause jaundice (yellowing of skin and eye), unexplained bruising, low blood sugar and electrolyte imbalance in the neonates (newborn baby). Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast Feeding

Consult your doctor

Lupiclor 12.5 mg Tablet should not be used when breastfeeding unless clearly necessary. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please talk to your doctor.

Driving

Unsafe

Driving after taking Lupiclor 12.5 mg Tablet is not recommended as it may occasionally cause drowsiness.

Liver

Caution

Lupiclor 12.5 mg Tablet to be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.

Kidney

Caution

Lupiclor 12.5 mg Tablet to be taken with caution, especially if you have a history of kidney diseases/conditions. Your doctor may adjust your dose depending upon your current kidney conditions.

Children

Caution

Lupiclor 12.5 mg Tablet to be taken with caution, especially if you are children below the age of 12. Your doctor may adjust your dose depending upon your age.

Heart

Safe if prescribed

Lupiclor 12.5 mg Tablet is safe for use in heart patients if recommended by the physician.

Geriatrics

Caution

Lupiclor 12.5 mg Tablet should be used under caution in geriatric patients. Please consult your physician.

What if I have taken an overdose of Lupiclor 12.5 mg Tablet

Do not take more than the prescribed dose of Lupiclor 12.5 mg Tablet as it may cause serious side effects. The symptoms of overdose include drowsiness, dizziness, nausea, weakness, muscle pain, extreme thirst, or rapid heartbeats. If you suspect you have taken an overdose, seek immediate medical attention.

Diet & Lifestyle Advise

Monitor your sodium intake: Reduce the amount of salt in your meals and avoid processed foods, as excess sodium can prevent Lupiclor 12.5 mg Tablet from working effectively.
Eat potassium-rich foods: Since this medicine can cause your body to lose potassium, include foods like bananas, oranges, spinach, and sweet potatoes in your diet if recommended by your doctor.
Stay safely hydrated: Ask your doctor how much fluid you should drink each day, as getting dehydrated can increase the risk of dizziness and kidney strain.
Limit alcohol consumption: Avoid or strictly limit alcohol, as it can combine with your medicine to cause a sudden, severe drop in blood pressure.
Track your blood pressure: Keep a daily log of your blood pressure readings at home to share with your doctor during your routine check-ups.

Have a query?

How Soon It Starts Working

The time required for Lupiclor 12.5 mg Tablet to start to work: The time required for Lupiclor 12.5 mg Tablet to start to work is 3 hours after administration.
The time for which the effects of Lupiclor 12.5 mg Tablet last: The effect of Lupiclor 12.5 mg Tablet lasts for 24 hours.

What if you forget to take Lupiclor 12.5 mg Tablet

If you miss a dose of Lupiclor 12.5 mg Tablet , take it as soon as you remember. However, if it is almost time for the next dose, skip the missed one and continue with your regular schedule. Do not take a double dose to make up for the missed one.

Storage

• Store Lupiclor 12.5 mg Tablet tablets at room temperature, ideally between 68°F and 77°F (20°C and 25°C). • Keep the medication inside its original container, tightly closed, to protect it from moisture and direct light. Do not store this medicine in your bathroom

Drug Warnings

Stand Up Slowly: Stand up slowly from a sitting or lying position to help reduce the risk of dizziness, lightheadedness, and fainting.
Protect Your Skin from Sunlight: Avoid excessive exposure to direct sunlight, as this medicine may increase your sensitivity to sunburn. Wear protective clothing and apply sunscreen when outdoors.
Attend Regular Blood Tests: Keep all scheduled blood test appointments so your doctor can monitor your kidney function and electrolyte levels regularly.
Monitor Blood Sugar Levels: If you have diabetes, check your blood sugar levels closely, as this medicine may occasionally cause blood sugar levels to increase.
Inform Healthcare Providers Before Procedures: Tell your dentist, surgeon, or other healthcare providers that you are taking Lupiclor 12.5 mg Tablet before undergoing any medical or dental procedures.

Drug-Drug Interactions

Drug-Drug Interactions

Inform your doctor if you are taking any of the following medicines, as they may interact with Lupiclor 12.5 mg Tablet :

Lithium: Taking Lupiclor 12.5 mg Tablet can reduce how quickly your body clears lithium, raising it to dangerous, toxic levels in your bloodstream.
NSAIDs (like ibuprofen or naproxen): These common pain relievers can reduce the effectiveness of Lupiclor 12.5 mg Tablet and increase your risk of kidney damage.
Other blood pressure medications: Combining this medicine with other drugs that lower blood pressure can increase the risk of your blood pressure dropping too low.
Digoxin: Low potassium levels caused by Lupiclor 12.5 mg Tablet can increase your risk of developing serious, toxic side effects from digoxin.

Drug-Food Interactions

Certain foods, beverages, and dietary products may affect how Lupiclor 12.5 mg Tablet works or increase the risk of side effects. Examples include:

Natural Liquorice: Eating natural liquorice can worsen potassium loss when combined with this medication.

Drug-Disease Interactions

Inform your doctor if you have any of the following medical conditions before taking Lupiclor 12.5 mg Tablet , as additional monitoring or treatment adjustments may be required:

Anuria (Inability to urinate): Do not take this medicine if you are unable to pass urine, as it relies on active kidney function to work.
Gout: This medicine can raise uric acid levels in your blood, which may trigger or worsen painful gout attacks.
Diabetes: Lupiclor 12.5 mg Tablet can affect your blood sugar control, which may require your doctor to adjust your diabetes medications.

chlorthalidoneCisapride

Critical

chlorthalidonePimozide

Severe

Drug-Drug Interactions

chlorthalidoneCisapride

Critical

How does the drug interact with Lupiclor 12.5 Tablet:
Co-administration of Lupiclor 12.5 Tablet and cisapride may increase the risk or severity of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Lupiclor 12.5 Tablet with Cisapride is not recommended, please consult your doctor before taking it. Do not discontinue the medication without consulting a doctor.

chlorthalidonePimozide

Severe

How does the drug interact with Lupiclor 12.5 Tablet:
Co-administration of Lupiclor 12.5 Tablet with pimozide can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Although there is an interaction, Lupiclor 12.5 Tablet can be taken with pimozide if prescribed by the doctor. Consult the prescriber if you develop sudden dizziness, lightheadedness, fainting, or fast or pounding heartbeats during treatment with pimozide. Also, let the doctor know if you experience signs of electrolyte disturbance, such as weakness, tiredness, drowsiness, confusion, muscle pain, cramps, dizziness, nausea, or vomiting. Do not discontinue any medications without consulting a doctor.

chlorthalidoneZiprasidone

Severe

How does the drug interact with Lupiclor 12.5 Tablet:
Co-administration of Lupiclor 12.5 Tablet with ziprasidone can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Although there is an interaction, Lupiclor 12.5 Tablet can be taken with ziprasidone if prescribed by the doctor. but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, weakness, tiredness, drowsiness, confusion, muscle pain, cramps, nausea, or vomiting. Do not discontinue any medications without consulting a doctor.

chlorthalidoneTizanidine

Severe

How does the drug interact with Lupiclor 12.5 Tablet:
Co-administration of Tizanidine and Lupiclor 12.5 Tablet may show additive effects and increase the risk of low blood pressure.

How to manage the interaction:
Although there is an interaction, Lupiclor 12.5 Tablet can be taken with tizanidine if prescribed by the doctor. If you experience headache, dizziness, palpitations, or sweating, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.

chlorthalidoneDroperidol

Severe

How does the drug interact with Lupiclor 12.5 Tablet:
Taking Droperidol can make Lupiclor 12.5 Tablet less effective in lowering blood pressure.

How to manage the interaction:
Taking Lupiclor 12.5 Tablet with Droperidol together can possibly result in an interaction, but it can be taken if your doctor has advised it. If you have any of these symptoms, it's important to contact your doctor right away. These symptoms include an irregular heart rhythm, severe or long-lasting diarrhea or vomiting, complications, sudden dizziness or lightheadedness, fainting, difficulty breathing, heart palpitations, weakness, feeling sleepy or confused, muscle pain, and feeling nauseous or vomiting. Do not stop using any medications without first talking to your doctor.

chlorthalidoneArsenic trioxide

Severe

How does the drug interact with Lupiclor 12.5 Tablet:
Taking Lupiclor 12.5 Tablet can make the body eliminate Arsenic trioxide faster, leading to lower levels in the blood and potentially reducing its effectiveness.

How to manage the interaction:
Co-administration of Lupiclor 12.5 Tablet with Arsenic trioxide can possibly result in an interaction, but it can be taken if a doctor has advised it. If you have any of these symptoms, it's important to contact a doctor right away: your heart beating irregularly, feeling dizzy or lightheaded, fainting, having a fast or pounding heartbeat, feeling weak or drowsy, being confused, experiencing muscle pain, or feeling nauseous or vomiting. Do not discontinue any medications without consulting a doctor.

chlorthalidoneAmiodarone

Severe

How does the drug interact with Lupiclor 12.5 Tablet:
Coadministration of Lupiclor 12.5 Tablet with amiodarone may increase the risk of abnormal heart rhythms.

How to manage the interaction:
Although taking Lupiclor 12.5 Tablet with amiodarone may cause an interaction, it is safe to do so if your doctor has prescribed it. If you have a cardiac problem or electrolyte imbalances, you may be more vulnerable. If you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or a rapid heartbeat, consult a doctor. Do not stop taking any medications without visiting a doctor.

chlorthalidoneLithium

Severe

How does the drug interact with Lupiclor 12.5 Tablet:
Co-administration of Lupiclor 12.5 Tablet together with lithium can increase the effects of lithium.

How to manage the interaction:
Although there is a interaction between Lupiclor 12.5 Tablet and lithium, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience diarrhea, vomiting, drowsiness, shaking of hands and legs, thirst, increased urination, lack of coordination, or muscle weakness. Do not discontinue any medications without consulting a doctor.

chlorthalidoneAminolevulinic acid

Severe

How does the drug interact with Lupiclor 12.5 Tablet:
Co-administration of Aminolevulinic acid and Lupiclor 12.5 Tablet may increase the risk of severe sunburn.

How to manage the interaction:
Taking Lupiclor 12.5 Tablet with Aminolevulinic acid together can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice that your skin is very sensitive to sunlight or if you have a really bad sunburn, it's important to contact your doctor right away. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

Therapeutic Class

[ANTI- HYPERTENSIVES]

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Author Details

Written By

Bayyarapu Mahesh Kumar
M Pharmacy

Reviewed By

Dr Aneela Siddabathuni
MPharma., PhD

Last Updated

Jun 26, 2026 | 1:18 PM IST

We provide you with authentic, trustworthy and relevant information.

See our editorial policy

Reference

Country of origin

India

Manufacturer/Marketer address

Lupin Ltd, 3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India Country of Origin: India

Other Info - LUP0336

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Lupiclor 12.5 Tablet 15's

Delivery Information

More about the Product

Composition :

Manufacturer/Marketer :

Consume Type :

Expires on or after :

Return Policy :

About Lupiclor 12.5 mg Tablet

Uses of Lupiclor 12.5 mg Tablet

Key Benefits

High Uric Acid Levels In Blood

Low Potassium Levels In Blood

High Levels Of Fat In Blood

Low Blood Pressure

Erectile Dysfunction

Dizziness

Drop In Blood Pressure Upon Standing Up

Directions for Use

How Lupiclor 12.5 mg Tablet Works

Alcohol

Pregnancy

Breast Feeding

Driving

Liver

Kidney

Children

Heart

Geriatrics

What if I have taken an overdose of Lupiclor 12.5 mg Tablet

Diet & Lifestyle Advise

How Soon It Starts Working

What if you forget to take Lupiclor 12.5 mg Tablet

Storage

Drug Warnings

Drug-Drug Interactions

Drug-Drug Interactions

Drug-Food Interactions

Drug-Food Interactions

All Substitutes & Brand Comparisons

New CH 12.5 mg Tablet 10's

CLORIDONE 12.5MG TABLET 10'S

Thalton 12.5mg Tablet

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FAQs

What is the use of Lupiclor 12.5 mg Tablet ?

How does Lupiclor 12.5 mg Tablet work?

Can taking Lupiclor 12.5 mg Tablet cause dehydration?

Will Lupiclor 12.5 mg Tablet affect my fertility?

How long can Lupiclor 12.5 mg Tablet be taken?

Is Lupiclor 12.5 mg Tablet a diuretic?

Can Lupiclor 12.5 mg Tablet be taken every day?

Can I drink alcohol while taking Lupiclor 12.5 mg Tablet ?

What happens if I take more than the recommended dose of Lupiclor 12.5 mg Tablet ?

Can I take ibuprofen with Lupiclor 12.5 mg Tablet ?

Does Lupiclor 12.5 mg Tablet increase uric acid? Can it cause gout?

Does Lupiclor 12.5 mg Tablet cause skin cancer?

What are the side effects of Lupiclor 12.5 mg Tablet ?

Can I take Lupiclor 12.5 mg Tablet before going to bed?

How long does it take for Lupiclor 12.5 mg Tablet to start working?

Does Lupiclor 12.5 mg Tablet cause potassium loss?

Can I drink alcohol while taking Lupiclor 12.5 mg Tablet ?

What should I do if I get muscle cramps while taking Lupiclor 12.5 mg Tablet ?

Is Lupiclor 12.5 mg Tablet safe to take during pregnancy?

Does Lupiclor 12.5 mg Tablet make your skin sensitive to the sun?

Can I stop taking Lupiclor 12.5 mg Tablet once my blood pressure is normal?

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