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  3. Megprate CR 200 Tablet 10's

Megprate CR 200 Tablet 10's, Pack of 10 TABLETS
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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Megprate CR 200 Tablet is used to treat seizures. Besides this, it is also used to treat manic episodes associated with bipolar disorder and prevent migraine symptoms. It contains Valproic acid which works by reducing abnormal electrical activity in the brain. It also produces a calming effect and limits the transmission of pain signals. This medicine may sometimes cause side effects such as nausea, upset stomach, tremors, sleepiness, headache, and weight gain. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Composition :

VALPROIC ACID-200MG

Manufacturer/Marketer :

Megma Healthcare Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Megprate CR 200 Tablet

Megprate CR 200 Tablet belongs to a group of anticonvulsants or anti-epileptics used to treat epilepsy/seizures/fits. In addition, Megprate CR 200 Tablet also treats manic episodes associated with bipolar disorder. Besides this, it can also prevent migraine symptoms (like a headache). Epilepsy is a sudden rush of electricity in the brain. In epilepsy, the brain's electrical rhythms become imbalanced, resulting in recurrent seizures, sometimes leading to an unconscious state.

Megprate CR 200 Tablet contains Valproic acid, which reduces the brain's excessive and aberrant nerve activity. As a result, it aids in the control of seizures. Megprate CR 200 Tablet raises the concentration of a chemical molecule known as GABA, which helps to stop nerve communication across the brain and has a calming effect. This contributes to the treatment of bipolar disorder. Megprate CR 200 Tablet limits the transmission of nerve pain, thereby preventing migraine headaches.

Megprate CR 200 Tablet should be taken as prescribed by the doctor. You may sometimes experience nausea, upset stomach or stomach pain, tremors (shakes), sleepiness, headache, weight gain and thinning hair. Most of these side effects are temporary and will go away on their own. However, if you suffer these adverse effects on a regular basis, you should consult your doctor.

Inform your doctor if you are allergic to any components present in Megprate CR 200 Tablet . If you are pregnant, do not take Megprate CR 200 Tablet because it may cause serious congenital defects. Use effective contraception if you are of childbearing age while taking Megprate CR 200 Tablet . If you are breastfeeding, inform your doctor before taking Megprate CR 200 Tablet . As Megprate CR 200 Tablet causes sleepiness and dizziness, do not drive or operate machinery. Avoid drinking alcohol with Megprate CR 200 Tablet as it may cause dizziness and tiredness. To rule out any negative effects, keep your doctor updated about your health condition and medications.

Uses of Megprate CR 200 Tablet

Megprate CR 200 Tablet is used for the treatment of Epilepsy (fits), Bipolar disorder, Migraine.

Directions for Use

• Megprate CR 200 Tablet can be taken with food to avoid stomach upset.• It is usually taken twice daily; however, your doctor may adjust the dosage and timing based on your medical condition and response to treatment.• Swallow Megprate CR 200 Tablet as a whole with a glass of water.• Do not crush or chew this medication.

Medicinal Benefits

Megprate CR 200 Tablet contains Valproic acid, an anticonvulsant (or anti-epileptic) medicine that reduces the brain's excessive and aberrant nerve activity. As a result, it aids in the control of seizures. Megprate CR 200 Tablet raises the concentration of a chemical molecule known as GABA, which helps to stop nerve communication across the brain and has a calming effect. This contributes to the treatment of bipolar disorder. Megprate CR 200 Tablet limits the transmission of nerve pain, thereby preventing migraine headaches.

How Megprate CR 200 Tablet Works

Megprate CR 200 Tablet contains Valproic acid, which reduces the brain's excessive and aberrant nerve activity. As a result, it aids in the control of seizures. Megprate CR 200 Tablet raises the concentration of a chemical molecule known as GABA, which helps to stop nerve communication across the brain and has a calming effect. This contributes to the treatment of bipolar disorder. Megprate CR 200 Tablet limits the transmission of nerve pain, thereby preventing migraine headaches.

Storage

Keep Megprate CR 200 Tablet out of the sight and reach of children.
Side effects of Megprate CR 200 Tablet
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Eat eggs for zinc and other nutrients that support healthy vision.
  • Consume blueberries as antioxidants to combat eye strain.
  • Include broccoli in your diet for diverse eye-boosting nutrients.
  • Eat sweet potatoes as a natural source of vitamin A.
  • Snack on almonds for vitamin E and eye protection.
  • Add tomatoes to your diet for lycopene and vision protection.
  • Perform exercises that improve binocular vision, such as dot-to-dot cards, coloring within lines, and Brock string tests.
  • Wear an eye patch and perform tasks like playing games and solving puzzles.
  • Patching and eye exercises can improve symptoms.
  • Get plenty of rest and sleep.
  • Keep your body warm.
  • Drink plenty of fluids to stay hydrated.
  • Avoid strenuous activities.
  • Maintain good hygiene to prevent flu from spreading.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

What if I have taken an overdose of Megprate CR 200 Tablet

Take Megprate CR 200 Tablet only as prescribed by the doctor. Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include sleepiness, irregular heartbeat, and coma (loss of consciousness for a period of time). If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

Before taking the Megprate CR 200 Tablet , let your doctor know about all your medical conditions, sensitivities, and all medications you are using. And also, inform your doctor if you are pregnant, suspect you are pregnant, plan to have a baby, or are breastfeeding. You should not become pregnant while you are receiving Megprate CR 200 Tablet . Consult your doctor immediately if you become pregnant while receiving a Megprate CR 200 Tablet . Alcohol should be avoided during treatment with this medicine. You must not drive or operate machinery while receiving Megprate CR 200 Tablet .

Drug-Drug Interactions

verifiedApollotooltip
DivalproexGlycerol phenylbutyrate
Critical
DivalproexMeropenem
Severe

Drug-Drug Interactions

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DivalproexGlycerol phenylbutyrate
Critical
How does the drug interact with Megprate CR 200 Tablet:
Coadministration of Glycerol phenylbutyrate and Megprate CR 200 Tablet can increase ammonia levels in the blood.

How to manage the interaction:
Taking Glycerol phenylbutyrate and Megprate CR 200 Tablet together is generally avoided as it can lead to an interaction, it can be taken when your doctor advises. If you experience any symptoms like sudden dizziness, headaches, vomiting, and visual disturbances, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
DivalproexMeropenem
Severe
How does the drug interact with Megprate CR 200 Tablet:
Co-administration of Megprate CR 200 Tablet and Meropenem can reduce the blood levels of Megprate CR 200 Tablet sodium.

How to manage the interaction:
Co-administration of Megprate CR 200 Tablet with Meropenem can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not discontinue any medications without a doctor's advice.
DivalproexBexarotene
Severe
How does the drug interact with Megprate CR 200 Tablet:
Co-administration of Megprate CR 200 Tablet and Bexarotene can increase the risk of pancreatitis (inflammation of the pancreas).

How to manage the interaction:
Co-administration of Megprate CR 200 Tablet and Bexarotene can lead to an interaction, but it can be taken when advised by your doctor. However, if you experience any symptoms like nausea, vomiting, or stomach cramps, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
DivalproexTeriflunomide
Severe
How does the drug interact with Megprate CR 200 Tablet:
Co-administration of Megprate CR 200 Tablet and teriflunomide can increase the risk of liver problems.

How to manage the interaction:
Co-administration of Megprate CR 200 Tablet and teriflunomide can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any symptoms like fever, chills, joint pain, unusual bleeding, weakness, nausea, vomiting, stomach pain, dark urine, pale stools, and yellowing of the skin or eyes, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
DivalproexLeflunomide
Severe
How does the drug interact with Megprate CR 200 Tablet:
Co-administration of Megprate CR 200 Tablet and leflunomide can increase the risk of liver problems.

How to manage the interaction:
Although there is an interaction between Megprate CR 200 Tablet and leflunomide, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, and/or yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.
DivalproexVorinostat
Severe
How does the drug interact with Megprate CR 200 Tablet:
Coadministration of Megprate CR 200 Tablet and Vorinostat can increase the risk of bleeding.

How to manage the interaction:
Although there is a possible interaction between Megprate CR 200 Tablet and Vorinostat, you can take these medicines together if prescribed by your doctor. If you experience any symptoms like unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult the doctor immediately. Do not discontinue any medications without consulting your doctor.
DivalproexBuprenorphine
Severe
How does the drug interact with Megprate CR 200 Tablet:
Co-administration of buprenorphine with Megprate CR 200 Tablet may increase the risk of developing side effects.

How to manage the interaction:
Co-administration of Buprenorphine with Megprate CR 200 Tablet can result in an interaction, it can be taken when a doctor has advised it. However, if you experience shortness of breath, irregular heart rhythms, nausea, vomiting, and diarrhea contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
DivalproexLamotrigine
Severe
How does the drug interact with Megprate CR 200 Tablet:
Coadministration of Megprate CR 200 Tablet and Lamotrigine can increase the risk and severity of side effects.

How to manage the interaction:
Although there is a possible interaction between Megprate CR 200 Tablet and Lamotrigine, you can take these medicines together if prescribed by your doctor. However, contact your doctor if you experience restlessness, rash, or muscle weakness. Do not stop using any medications without a doctor's advice.
DivalproexSodium oxybate
Severe
How does the drug interact with Megprate CR 200 Tablet:
Co-administration of Sodium oxybate and Megprate CR 200 Tablet can increase the risk of developing side effects.

How to manage the interaction:
Co-administration of Sodium oxybate and Megprate CR 200 Tablet can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any symptoms like dizziness, sweating, palpitations, and shortness of breath, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
DivalproexLomitapide
Severe
How does the drug interact with Megprate CR 200 Tablet:
Co-administration of Megprate CR 200 Tablet and Lomitapide can increase the risk of liver problems.

How to manage the interaction:
Co-administration of Megprate CR 200 Tablet and lomitapide can lead to an interaction, but it can be taken if advised by your doctor. However, if you experience any symptoms like fever, joint pain, unusual bleeding, weakness, nausea, vomiting, stomach pain, dark urine, pale stools, or yellowing of the skin or eyes, consult the doctor immediately. Do not stop using any medications without the doctor's advice.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Adolescents and adults are advised to follow the Atkins diet (high fat, low carbohydrate).
  • Exercising on a regular basis aids with weight maintenance and general health.
  • Rest well, and get plenty of sleep.
  • Avoid smoking and drinking alcohol.
  • Meditation and yoga can help reduce stress, reduce pain sensitivity, and increase coping abilities.
  • Have a seizure response plan in place, and make sure everyone around you knows what to do in the event of a seizure.
  • Prepare your living environment; simple changes may help reduce the risk of physical damage during a seizure.
  • Understand what causes seizures and try to reduce or avoid them.
  • Please keep your overall health in mind, as it can aid in the reduction of seizure activity.
  • Install an alarm or an emergency gadget to summon help during a seizure attack.

Habit Forming

No

Therapeutic Class

ANTICONVULSANT

Megprate CR 200 Tablet Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Caution

Do not consume alcohol while taking Megprate CR 200 Tablet as alcohol can worsen the side effects of the Megprate CR 200 Tablet , including sleepiness and dizziness.

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Pregnancy

Unsafe

Megprate CR 200 Tablet is a Category D pregnancy drug. It is not recommended for use during pregnancy as it may cause an increase in the risk of a cleft lip, which is a congenital disability in the unborn baby. If you are a female able to have a baby, you must use an effective method of birth control (contraception) without interruption during your entire treatment with Megprate CR 200 Tablet .

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Breast Feeding

Caution

Megprate CR 200 Tablet passes into breast milk and may harm your infant. Please consult a doctor if you are breastfeeding before taking Megprate CR 200 Tablet . Breastfed infants are at risk for valproic acid-induced hepatotoxicity, so infants should be monitored for jaundice and other signs of liver damage during maternal therapy.

bannner image

Driving

Caution

Megprate CR 200 Tablet may cause dizziness, drowsiness or tiredness in some people. Therefore, avoid driving if you feel drowsy, dizzy or tired after taking Megprate CR 200 Tablet .

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Liver

Caution

Inform your doctor before receiving the Megprate CR 200 Tablet if you have a history of liver diseases/conditions. Extreme caution is recommended in patients with impaired liver function. Your doctor will weigh the benefits and potential risks before prescribing Megprate CR 200 Tablet .

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please inform your doctor if you have kidney impairment.

bannner image

Children

Consult your doctor

Use is not recommended for children less than ten years. Your doctor will decide the dose based on your child's condition if more than ten years.

Have a query?

FAQs

Megprate CR 200 Tablet is used to treat epilepsy/seizures/fits. In addition, it also helps treat manic episodes associated with bipolar disorder and prevent migraine symptoms (like a headache).

Megprate CR 200 Tablet decreases the excessive and abnormal nerve activity in the brain. Thereby helping in controlling seizures.

Megprate CR 200 Tablet helps to treat manic episodes associated with bipolar disorder by increasing the amount of a chemical substance called GABA; this helps block nerve transmission across the brain and provides a calming effect.

Megprate CR 200 Tablet limits the transmission of nerve pain, thereby preventing migraine headaches. Migraine is a neurological condition which is characterized by intense headaches.

Megprate CR 200 Tablet may cause weight gain due to an increase in appetite. Maintain a healthy weight by following a healthy diet and exercising regularly.

Use an effective method of contraception during the treatment with Megprate CR 200 Tablet . Avoid getting pregnant while taking Megprate CR 200 Tablet as it could lead to serious birth defects. Do not stop taking Megprate CR 200 Tablet and consult your doctor immediately if you become pregnant.

Megprate CR 200 Tablet may cause weight gain due to an increase in appetite. Maintain a healthy weight by following a healthy diet and exercising regularly.

Megprate CR 200 Tablet may cause common side effects such as nausea, vomiting, headache, sleepiness, tremor, weakness, dizziness, stomach pain, and weight gain. If these side effects persist or worsen, please consult your doctor.

Megprate CR 200 Tablet contains Valproic acid as its active ingredient.

Take Megprate CR 200 Tablet with or without food as advised by your doctor.

You are recommended to avoid alcohol consumption while taking Megprate CR 200 Tablet as it may worsen the side effects of the Megprate CR 200 Tablet , including sleepiness and dizziness.

No, Megprate CR 200 Tablet does not cause addiction. However, Megprate CR 200 Tablet should be used as per dose and duration prescribed by your doctor. Do not self-medicate.

Megprate CR 200 Tablet does not cure epilepsy, it only helps to prevent the seizures. However, you have to take Megprate CR 200 Tablet for as long as it is advised by your doctor. If you face any difficulty while taking Megprate CR 200 Tablet , consult your doctor.

If you stop taking Megprate CR 200 Tablet suddenly, it may increase the risk of recurrence of seizures. Therefore, it should be stopped gradually. If you feel the need to stop taking Megprate CR 200 Tablet , please consult your doctor.

Some birth control pills (oestrogen-containing birth control pills) may lower the levels of Megprate CR 200 Tablet in blood. Thus, inform your doctor if you are using birth control pills and discuss with your doctor about the suitable method of contraception.

Megprate CR 200 Tablet is safe to take for long time in many patients if prescribed by a doctor. In rare cases, prolonged use of Megprate CR 200 Tablet may weaken your bones, thereby increasing their risk of breaking easily (osteopenia and osteoporosis). Get regular checkups done for bone health if you are taking Megprate CR 200 Tablet for a long time.

Megprate CR 200 Tablet may cause hair thinning, hair colour changes and even hair loss. If you have any concerns regarding this, please ask your doctor if it is possible to lower the dose of Megprate CR 200 Tablet . Your hair may regrow after either lowering your dose or changing medication.

Country of origin

India

Manufacturer/Marketer address

No. 1065, Street No. 1, Haripur, Sector - 4,, Panchkula, 160022.
Other Info - MEG0642

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Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 6:47 AM IST

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Reference

  1. https://www.drugs.com/mtm/valproic-acid.html
  2. https://www.medicines.org.uk/emc/files/pil.6102.pdf
  3. https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/018081s065_018082s048lbl.pdf
  4. https://www.nhs.uk/medicines/valproic-acid/
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