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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Mesacol Enema is treating ulcerative colitis and ulcerative proctitis. It contains Mesalamine, which works by preventing the synthesis of chemical messengers such as prostaglandins in the intestines that produce inflammation (swelling). This lowers ulceration, bleeding, and stomach pain while preventing future illness flare-ups. Common side effects of Mesacol Enema are diarrhoea, stomach pain, headache or nausea.

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Composition :

MESALAMINE-4GM

Manufacturer/Marketer :

Sun Pharmaceutical Industries Ltd

Consume Type :

Rectal

Expires on or after :

Return Policy :

Not Returnable

About Mesacol Enema

Mesacol Enema is used to treat ulcerative colitis and ulcerative proctitis. Ulcerative colitis is a chronic inflammatory bowel disease that causes inflammation of the large intestine lining (colon). Ulcerative proctitis is a condition in which ulcerative colitis solely affects the rear channel (rectum).

Mesacol Enema contains Mesalamine, which works by preventing the synthesis of chemical messengers such as prostaglandins in the intestines that produce inflammation (swelling).

Sometimes, you may experience diarrhoea, stomach pain, headache or nausea. Most of these side effects of Mesacol Enema do not require medical attention and typically resolve on their own over time. However, if the side effects persist or worsen, please consult your doctor.

Follow your doctor's instructions on the dosage and timing of this medication. Mesacol Enema is for rectal use only. It is advised to wash your hands before and after applying the medicament. Ensure the rectal area is clean and dry before application.

Inform your doctor if you are allergic to any components present in Mesacol Enema. Mesacol Enema should be used with caution in the elderly. If you are pregnant or breastfeeding, please inform your doctor before taking Mesacol Enema. Avoid taking Mesacol Enema if you have severe kidney failure. If you have stomach pain, cramps, severe headache, fever or rash, after taking Mesacol Enema, stop taking it immediately and consult a doctor.

Uses of Mesacol Enema

Mesacol Enema is used in the treatment of Ulcerative colitis and Ulcerative proctitis. The detailed uses of Mesacol Enema are as follows:

  • Management of Irritable Bowel Syndrome (IBS): Mesacol Enema helps manage IBS symptoms like bloating, gas, and abdominal discomfort.
  • Support for Ulcerative Colitis: Mesacol Enema supports ulcerative colitis management by reducing flare-ups and promoting gut health.

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Directions for Use

  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Check the label for directions and use it as advised by the doctor. 
  • Before using, empty your bowels (if necessary) and wash your hands. Shake the bottle vigorously for at least 30 seconds. Remove the applicator's protective cap and hold the bottle by its top end. Lie on your left side, your left leg extended and your right leg bent. Insert the applicator (lubricant-coated) for easier entry into the rectum. Squeeze the bottle gently while holding it directed towards your navel. When the bottle is empty, remove the applicator from the rectum.
  • Allow the drug to spread throughout the lower section of the large intestine for at least 30 minutes by remaining in this posture.
  • Wash your hands before and after applying the medicament. Make sure that the rectal area is clean and dry before application.
  • For rectal use only.

Key Benefits

  • Mesacol Enema contains Mesalamine, an anti-inflammatory drug used to treat ulcerative colitis and ulcerative proctitis.
  • This medicine helps reduce inflammation (redness and swelling) in the intestines and provides relief from symptoms such as stomach pain or bleeding.
  • Mesacol Enema may also prevent further episodes of ulcerative colitis.

How Mesacol Enema Works

Mesacol Enema contains Mesalamine, which works by preventing the synthesis of chemical messengers such as prostaglandins in the intestines that produce inflammation (swelling). This lowers ulceration, bleeding, and stomach pain while preventing future illness flare-ups.

Storage

Store in a cool and dry place away from sunlight
Side effects of Mesacol Enema 60 ml
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
Here are the 7 step-by-step strategies to manage the side effect of "inability to sleep" caused by medication usage:
  • Prepare for a restful night's sleep: Develop a calming pre-sleep routine, like reading or meditation, to help your body relax and prepare for sleep.
  • Create a sleep-conducive Environment: Make bedroom a sleep haven by ensuring it is quiet, dark and calm.
  • Follow a Sleep Schedule: Go to bed and get up at the same time every day to help regulate your body's internal clock and increase sleep quality.
  • Try relaxing techniques like deep breathing, mindfulness meditation and any others.
  • Limit stimulating activities before bedtime: Avoid stimulating activities before bedtime to improve sleep quality.
  • Monitor Progress: Keep track of your sleep patterns to identify areas for improvement.
  • Consult a doctor if needed: If these steps don't improve your sleep, consult a doctor for further guidance and therapy.

What if I have taken an overdose of Mesacol Enema

Please do not exceed the recommended dose, as it might cause an overdose. Using more medication will not improve your symptoms; instead, they may cause serious side effects or poisoning. This medicine may be harmful if swallowed. Seek emergency medical attention or call your doctor if you notice any unusual symptoms or if anyone has accidentally swallowed the medication.

Drug Warnings

  • Infor your doctor if oyu are allergic to it or any other components.
  • Mesacol Enema should be used with caution in the elderly.
  • Avoid taking Mesacol Enema if you have severe kidney failure.
  • Do not use Mesacol Enema if you are pregnant, planning to become pregnant, or breastfeeding without first consulting the doctor.
  • Mesacol Enema is recommended not to be used in populations with severe renal or hepatic impairment, so inform your doctor if you have severe renal or hepatic impairment.
  • Use Mesacol Enema in dose and duration as advised by a doctor only.
  • Mesacol Enema is for rectal use. Do not swallow it. In case of accidental swallowing, drink plenty of water and consult a doctor immediately.
  • $nam is not recommended for use in children.

Drug-Drug Interactions

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No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

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Diet & Lifestyle Advise

  • Maintain a low-fat diet and eat foods rich in vitamin C, such as bell peppers, spinach, parsley and berries, which help heal faster.
  • Opt for food and drinks high in Omega 3 fatty acids to relieve pain, swelling, and inflammation. Omega 3 rich acid-enriched foods include flaxseeds, walnut, soybean oil, salmon, and tuna if you prefer non-veg.
  • Eat more fibre-rich foods such as fruits and vegetables.
  • Eat smaller meals all day.
  • Drink small amounts of water throughout the day.
  • If you are intolerant to lactose, lower your intake of milk.
  • Avoid foods high in sugar, fat, and processed foods, as these, may cause inflammation.
  • Try to avoid alcohol as it can affect your stomach and intestine and also limits the absorption of the important nutrients required by your body.

Habit Forming

No

Therapeutic Class

[ANTI- INFLAMMATORY AGENTS]

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Alcohol

Safe if prescribed

The interaction of alcohol with Mesacol Enema is unknown. However, avoid consuming alcohol while on treatment with this medicine.

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Pregnancy

Consult your doctor

Mesacol Enema should not be used in pregnancy unless necessary. So, inform your doctor if you are pregnant or suspect pregnancy.

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Breast Feeding

Consult your doctor

Mesacol Enema should not be used while breastfeeding unless necessary. So, inform your doctor if you are a nursing mother.

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Driving

Safe if prescribed

Mesacol Enema usually does not affect your ability to drive or operate machinery.

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Liver

Consult your doctor

Inform your doctor before using Mesacol Enema if you have a history of liver disease. It should be used cautiously in patients with mild to moderately impaired liver function. It is not recommended for use in populations with severe liver impairment.

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Kidney

Consult your doctor

Inform your doctor before using Mesacol Enema if you have a history of kidney disease. It should be used cautiously in patients with mild to moderately impaired kidney function. It is not recommended for use in populations with severe kidney impairment.

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Children

Safe if prescribed

Mesacol Enema is intended for adults. Not recommended for children.

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Heart

Inform your doctor before receiving the Mesacol Enema if you have heart disease. Your doctor will prescribe only if the benefits outweigh the risks.

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Geriatrics

Consult your doctor

Mesacol Enema should be used in the elderly only if advised by a doctor, as dose adjustment may be required.

FAQs

Mesacol Enema is used to treat ulcerative colitis and ulcerative proctitis.

Mesacol Enema contains Mesalamine, which works by inhibiting the production of certain chemical substances, such as prostaglandins, that cause pain and swelling. Thus, it helps reduce inflammation (swelling) in the intestines and relieves stomach pain or bleeding symptoms.

Mesacol Enema may cause diarrhoea as a common side effect. However, if the condition persists or worsens with fever, watery stools or consistent stomach pain, please consult a doctor. Also, drink plenty of water while using Mesacol Enema to prevent dehydration.

If you miss a dosage of mesalamine, take it as soon as you remember unless your next dose is approaching. In this situation, skip the missed dose and resume your regular schedule. Do not combine two doses to make up for a missed dosage.

You are recommended not to take Mesacol Enema with other medications without doctor's notice, especially immunosuppressant medications such as Azathioprine.

No, you are not recommended to stop using Mesacol Enema suddenly as it may cause recurring symptoms. Therefore, use Mesacol Enema for as long as your doctor has prescribed it, and if you experience any difficulty while using Mesacol Enema, please consult your doctor.

Country of origin

India

Manufacturer/Marketer address

Sun Pharmaceutical Industries Ltd., SUN HOUSE, CTS No. 201 B/1, Western Express Highway, Goregaon (E), Mumbai 400063
Other Info - MES0002

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