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compositionComposition:OBETICHOLIC ACID-10MG
prescription
Prescription Medicine
info
Obetohep-10 Tablet 10's
Obetohep-10 Tablet 10's
Obetohep-10 Tablet 10's
Obetohep-10 Tablet 10's
Obetohep-10 Tablet 10's

Obetohep-10 Tablet is used to treat primary biliary cirrhosis (an autoimmune disease caused by damage of bile ducts in the liver). This medicine helps reduce bile acid buildup in the liver and slows the progression of liver damage and fibrosis.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

OBETICHOLIC ACID-10MG

Manufacturer/Marketer :

Alkem Laboratories Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Obetohep-10 Tablet

Obetohep-10 Tablet is used to treat primary biliary cirrhosis. Primary biliary cholangitis, also known as primary biliary cirrhosis, is an autoimmune disease caused by the build-up of bile in the liver, which leads to liver damage.  

Obetohep-10 Tablet contains Obeticholic acid, which helps improve liver function by reducing the production and build-up of bile in the liver.

Obetohep-10 Tablet may cause common side effects, including stomach pain, fatigue, dizziness, constipation, and palpitations. Most of these side effects do not require medical attention and will resolve gradually over time. However, talk to your doctor if the side effects persist or worsen.

Consult your doctor if you are pregnant or breastfeeding. Obetohep-10 Tablet is not recommended for children and adolescents. Obetohep-10 Tablet may cause dizziness, so drive with caution. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Uses of Obetohep-10 Tablet

Obetohep-10 Tablet is used in the treatment of Primary biliary cirrhosis. The detailed uses of Obetohep-10 Tablet are as follows:

  • Treat primary biliary cholangitis (PBC): Obetohep-10 Tablet is primarily used to manage PBC, a chronic autoimmune liver disease that damages bile ducts.

Key Benefits

  • Enhances liver health in individuals suffering from primary biliary cholangitis (PBC).
  • Lessens the liver's buildup of bile acids.
  • Reduces the fibrosis and inflammation of the liver.
  • Improves liver health by lowering alkaline phosphatase (ALP) levels.
Side effects of Obetohep-10 Tablet
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • Throat pain can worsen if there is no proper rest for your throat.
  • Drink plenty of warm fluids and frequently gargle with salt water.
  • Humidify the surrounding air using a humidifier, as dry air may increase dryness and throat pain.
  • Consider taking lozenges or hard candy throat pain relievers, which give a soothing effect.
  • Take enough rest and stay in warm places to reduce pain quickly.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
  • Avoid triggers like alcohol, caffeine, and energy drinks.
  • Try relaxation techniques such as yoga, meditation, or deep breathing.
  • Exercise regularly as it helps maintain heart health.
  • Follow a nutritious and balanced diet.
Here's a comprehensive approach to managing medication-triggered fever:
  • Inform your doctor immediately if you experience a fever after starting a new medication.
  • Your doctor may adjust your medication regimen or dosage as needed to minimize fever symptoms.
  • Monitor your body temperature to monitor fever progression.
  • Drink plenty of fluids, such as water or electrolyte-rich beverages, to help your body regulate temperature.
  • Get plenty of rest and engage in relaxation techniques, such as deep breathing or meditation, to help manage fever symptoms.
  • Under the guidance of your doctor, consider taking medication, such as acetaminophen or ibuprofen, to help reduce fever.
  • If your fever is extremely high (over 103°F), or if you experience severe symptoms such as confusion, seizures, or difficulty breathing, seek immediate medical attention.

Directions for Use

  • Obetohep-10 Tablet can be taken with food to prevent stomach upset.
  • It is usually taken once daily or as prescribed by your doctor.
  • Swallow Obetohep-10 Tablet as a whole with a glass of water.
  • Do not break, chew, or crush it.

How Obetohep-10 Tablet Works

Obetohep-10 Tablet contains Obeticholic acid, which helps improve liver function by reducing the production and build-up of bile in the liver, increasing the removal of bile from the liver, and reducing inflammation, thereby helping treat primary biliary cirrhosis.
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Alcohol

Consult your doctor

It is not known if alcohol interacts with Obetohep-10 Tablet . Consult your doctor if you have any concerns.

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Pregnancy

Consult your doctor

Please consult your doctor if you are pregnant, as limited information is available regarding the usage of Obetohep-10 Tablet during pregnancy.

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Breast Feeding

Consult your doctor

Consult your doctor if you are breastfeeding; your doctor will decide whether Obetohep-10 Tablet can be taken by breastfeeding mothers or not.

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Driving

Safe if prescribed

Obetohep-10 Tablet does not affect your ability to drive. However, you are advised to omit driving if you experience dizziness.

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Liver

Caution

Dose adjustment may be needed. Please consult your doctor if you have a liver impairment or any concerns regarding this. Inform your doctor if you have/had liver cirrhosis.

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Kidney

Consult your doctor

Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Obetohep-10 Tablet is not recommended for children or adolescents.

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Heart

Caution

Obetohep-10 Tablet should be used with caution in patients with heart disease due to increased risk of side effects. Therefore, please consult your doctor before using Obetohep-10 Tablet .

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Geriatrics

Caution

Obetohep-10 Tablet should be given with caution in elderly patients due to an increased risk of side effects. Please consult your doctor before using Obetohep-10 Tablet .

What if I have taken an overdose of Obetohep-10 Tablet

Take Obetohep-10 Tablet only as prescribed by the physician. Do not exceed the recommended dose, as it might cause an overdose. Symptoms of overdose may include yellowing of the skin or eyes, dark-coloured urine, loss of appetite, pain in the upper right part of the stomach, nausea, vomiting, or swelling in the area around the stomach. If you experience any of these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Diet & Lifestyle Advise

Healthy eating habits:

  • Eat a well-balanced diet rich in fruits and vegetables.
  • To lessen liver strain, cut back on processed, greasy, and fried foods.
  • Limit salt consumption to avoid fluid retention.

Lifestyle changes:

  • Maintain a healthy body weight with regular physical activity.
  • Avoid alcohol completely to protect the liver.

Physical activity:

  • Take part in mild to moderate physical activity, including cycling or walking.
  • Avoid intense exercises if you're tired or itchy.
  • To maintain a healthy weight and promote liver health, engage in regular exercise.
  • Incorporate stress-relieving moderate exercises like yoga or stretching.

Health Queries

I have been diagnosed with grade 2 fatty liver. What medicines, diet, and precautions should I follow to safely improve this condition?

Vikas Singh

Vikas Singh

M Pharmacy

Grade 2 fatty liver usually means excess fat has built up in the liver, and mild to moderate liver inflammation may be present. This condition is commonly linked with obesity, diabetes, high cholesterol, alcohol intake, unhealthy food habits, lack of exercise, or rapid weight gain. In many people, fatty liver can improve gradually with lifestyle changes and proper control of associated health problems. Weight reduction through regular exercise and balanced eating is one of the most important steps. Avoiding alcohol, oily foods, fried items, sugary drinks, excess sweets, and processed foods may help reduce liver fat over time. Eating more vegetables, fruits, whole grains, lean protein, and drinking enough water may support liver health naturally. Proper diabetes and cholesterol control are also very important because these conditions can worsen fatty liver. Medicines or supplements are sometimes advised depending on liver function tests, cholesterol levels, and overall health, but treatment should be individualised after medical evaluation. Avoid taking herbal or over-the-counter liver products without guidance because some may harm the liver further. Consult your doctor regularly for liver monitoring, especially if you develop abdominal swelling, jaundice, vomiting, severe weakness, or worsening liver reports.

I have an enlarged liver, and I also had gallbladder surgery earlier, along with diabetes. What precautions, diet, or treatment may help keep my liver healthy and prevent further problems?

Vikas Singh

Vikas Singh

M Pharmacy

An enlarged liver can happen due to fatty liver disease, diabetes, alcohol use, viral infections, obesity, certain medicines, or long-term metabolic problems. Since you also have diabetes and a history of gallbladder surgery, keeping the liver healthy becomes especially important because uncontrolled sugar and unhealthy food habits can put extra stress on the liver over time. Food choices play a major role in protecting liver function. Reducing oily foods, deep-fried items, excess sugar, alcohol, and processed foods may help lower fat buildup in the liver. Eating more vegetables, fruits, high-fibre foods, and balanced home-cooked meals is usually better for both liver health and diabetes control. Regular walking, maintaining a healthy weight, proper sleep, and timely diabetes management can also support gradual liver recovery. Liver-related medicines or supplements should only be used after proper medical advice because some products may actually worsen liver stress. Regular monitoring of liver function tests, blood sugar, and abdominal scans may help track progression. Swelling in the abdomen, yellow eyes, vomiting blood, severe weakness, or black stools should never be ignored.

Have a query?

How Soon It Starts Working

  • The time required for Obetohep-10 Tablet to start to work: The time required for Obetohep-10 Tablet to show its action is unknown.
  • The time for which the effects of Obetohep-10 Tablet last: The duration of action for Obetohep-10 Tablet is clinically unknown.

What if you forget to take Obetohep-10 Tablet

Take the missed dose as soon as possible. However, if it is time for the next dose, skip the missed dose and go back to your regular dosing schedule. Do not take a double dose to make up for your missed dose.

Storage

• Store in a cool and dry place away from sunlight.• Keep Obetohep-10 Tablet out of reach and sight of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • Do not take Obetohep-10 Tablet if you are allergic to any of its contents; if you have a complete blockage of the biliary tract (liver, bile ducts, and gall bladder).
  • Inform your doctor if you experience itching that is difficult to tolerate.
  • Consult your doctor if you are pregnant or breastfeeding.
  • Obetohep-10 Tablet is not recommended for children or adolescents.
  • Obetohep-10 Tablet may cause dizziness, so drive with caution.
  • Consult a doctor immediately if you experience yellowing of the skin/eyes, black/tarry stools, dark urine, coughing up/vomiting blood, confusion, slurred speech, mood swings, anxiety, swelling in and around the stomach.

Drug-Drug Interactions

verifiedApollotooltip

Drug-Drug Interactions: Taking Obetohep-10 Tablet with the following medications may cause adverse reactions.

  • Blood thinners (warfarin)
    • Potential effect: May alter the effectiveness of warfarin.
  • Bile acid sequestrants (cholestyramine, colestipol)
    • Potential effect: May reduce the absorption of these drugs.

Drug-Food Interactions: No interactions found/established.

Drug-Disease Interactions: Inform your doctor if you have a history of the following conditions before taking Obetohep-10 Tablet , as it may worsen your condition or cause complications.

  • Biliary obstruction
  • Liver impairment
Obeticholic acidTizanidine
Severe

Drug-Drug Interactions

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Obeticholic acidTizanidine
Severe
How does the drug interact with Obetohep-10 Tablet:
Coadministration of Tizanidine and Obetohep-10 Tablet can increase tizanidine's blood levels and risk of side effects.

How to manage the interaction:
Co-administration of Tizanidine and Obetohep-10 Tablet can lead to an interaction, but it can be taken if your doctor advises. However, contact your doctor immediately if you experience drowsiness, dizziness, lightheadedness, fainting, and irregular heart rhythm. Do not discontinue any medications without consulting your doctor.

Drug-Food Interactions

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OBETICHOLIC ACID-10MGCaffeine containing foods/drinks
Moderate

Drug-Food Interactions

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OBETICHOLIC ACID-10MGCaffeine containing foods/drinks
Moderate
Common Foods to Avoid:
Cocoa, Coffee, Dark Chocolate, Energy Drinks With Caffeine, Green Tea, Kola Nut, Tea, Tiramisu

How to manage the interaction:
Consumption of Caffeine-containing foods/drinks along with Obetohep-10 Tablet may increase the blood levels and side effects of caffeine. Avoid or limit caffeine consumption along with Obetohep-10 Tablet as it can increase the risk of developing side effects.

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FAQs

Obetohep-10 Tablet is used to treat primary biliary cirrhosis. Primary biliary cholangitis, also known as primary biliary cirrhosis, is an autoimmune disease caused by damage of bile ducts in the liver.
Obetohep-10 Tablet helps improve liver functioning by reducing the production and build-up of bile in the liver and reducing inflammation.
Do not discontinue Obetohep-10 Tablet without consulting your doctor. To treat your condition effectually, continue taking Obetohep-10 Tablet for as long as prescribed. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Obetohep-10 Tablet .
Constipation might be a side-effect of Obetohep-10 Tablet . Drink lots of fluids and eat fibre-rich food if you experience constipation. Talk to your doctor if you have severe constipation.
Consult your doctor before taking Obetohep-10 Tablet along with bile acid-binding resins, as they might lower the effect of Obetohep-10 Tablet . If prescribed, maintain a gap of 4-6hours between Obetohep-10 Tablet and bile acid-binding resins. Bile acid-binding resins are used to lower blood cholesterol levels.
Obetohep-10 Tablet may cause palpitation, a sensation that the heart is racing, pounding, or fluttering. A minor fluctuation should not be a worry; however, if palpitations continue or you begin to feel unwell, speak with your doctor.
Obetohep-10 Tablet is used to treat primary biliary cholangitis (PBC), an autoimmune liver disease. Adults with PBC and individuals who haven't responded to other treatments may need to take OCA, but only if advised by their doctor.
You can use Obetohep-10 Tablet combined with ursodeoxycholic acid to treat primary biliary cholangitis (PBC), but only if your doctor advises.
Before using this medication, you should inform your doctor about your medical history, including any ongoing medicines, to avoid potential interactions and minimise side effects.
Common side effects of Obetohep-10 Tablet may include stomach pain, tiredness, dizziness, constipation, and palpitations. Most of these side effects do not require medical attention and will resolve gradually. However, you are advised to talk to your doctor if the side effects persist or worsen.
Please consult your doctor if you are pregnant, as limited information is available regarding the usage of Obetohep-10 Tablet during pregnancy.
Obetohep-10 Tablet is not recommended for children or adolescents.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

Alkem Laboratories Limited, Devashish Building, Alkem House, Senapati Bapat Road, Lower Parel, Mumbai - 400 013.
Other Info - OBE0073

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