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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Planep Tablet is used to treat hypertension (high blood pressure). It also maintains the bloodstream's potassium level, removes excess water from the body, and prevents hypertension (high blood pressure) due to oedema (fluid retention). It contains Eplerenone, which works by increasing the amount of urine that is passed out from the kidneys. It effectively reduces excess fluid levels in the body and the heart's workload, making it more efficient at pumping blood throughout the body. Thus, it also helps lower high blood pressure, reducing the chances of any future heart attack, stroke, or angina (chest pain) in the future. In some cases, you may experience dehydration, electrolyte disturbances (calcium, magnesium, and sodium), constipation, itching, and increased uric acid.

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Whats That

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Composition :

EPLERENONE-25MG

Manufacturer/Marketer :

Lupin Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Planep Tablet

Planep Tablet is used to treat hypertension (high blood pressure). It also maintains the bloodstream's potassium level, removes excess water from the body, and prevents hypertension (high blood pressure) due to oedema (fluid retention). Blood pressure measures the force our heart uses to pump blood to all body parts. Hypertension is a chronic condition when blood pressure is too high. This condition can lead to hardened arteries (blood vessels), decreasing the blood and oxygen flow to the heart.

Planep Tablet contains Eplerenone, which is prescribed for the treatment of hypertension. Planep Tablet works by increasing the amount of urine passed out from the kidneys. It effectively reduces excess fluid levels in the body and the heart's workload, making it more efficient at pumping blood throughout the body. Thus, it also helps lower high blood pressure, reducing the chances of any future heart attack, stroke, or angina (chest pain).

Take Planep Tablet as prescribed by your doctor. Depending upon your medical condition, you are advised to take Planep Tablet for as long as your doctor has prescribed it for you. In some cases, you may experience dehydration, electrolyte disturbances (calcium, magnesium, and sodium), constipation, itching, and increased uric acid. Most of these side effects of Planep Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Try not to stop taking a Planep Tablet of your own, as doing so may raise your blood pressure, thereby increasing the risk of heart disease and stroke. Inform your doctor if you have any kidney disease (with creatinine clearance less than 30 mL/min), liver disease, high serum potassium (hyperkalemia), diabetes mellitus type 2, and patients with nil urine output (anuria). If you are pregnant or breastfeeding, please tell your doctor so that the dosage of Planep Tablet can be prescribed accordingly. Please tell your doctor if you are taking any other medicines or are allergic to the Planep Tablet . Reducing the amount of table salt (sodium chloride) in your food often relieves the body's swelling. Please take Planep Tablet at least 4 hours before sleeping to avoid frequent urination at night. Also, do not take Planep Tablet along with lithium to prevent serious side effects.

Uses of Planep Tablet

Treatment of Hypertension (high blood pressure) and oedema.

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Planep Tablet  primarily used to treat hypertension (high blood pressure) and heart failure. It also treats edema (reduces swelling) caused due to other conditions. Planep Tablet works by increasing the amount of urine passing from the kidneys. It effectively reduces excess fluid levels in the body, reduces the heart's workload, and makes the heart more efficient at pumping blood throughout the body. Thus, it also helps lower high blood pressure, reducing the chances of any future heart attack, stroke, or angina (chest pain) in the future.

How Planep Tablet Works

Planep Tablet contains Eplerenone, which is prescribed for the treatment of hypertension. Planep Tablet works by increasing the amount of urine passed out from the kidneys. It effectively reduces excess fluid levels in the body and the heart's workload, making it more efficient at pumping blood throughout the body. Thus, it also helps lower high blood pressure, reducing the chances of any future heart attack, stroke, or angina (chest pain).

Storage

Store in a cool and dry place away from sunlight

Side Effects of Planep Tablet

  • Dizziness
  • Nausea
  • Dizziness
  • Headache
  • Cough
  • Increased creatinine and potassium in the blood
  • Fatigue

What if I have taken an overdose of Planep Tablet

Do not take more than the prescribed dose of Planep Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Planep Tablet should not be given to the people allergic to Planep Tablet , have low blood pressure (less than 90 mm of Hg), have had a heart attack, kidney disease (with creatinine clearance less than 30 mL/min), liver disease, high serum potassium (hyperkalemia), diabetes mellitus type 2 and patients with nil urine output (anuria), pregnant women, planning to get pregnant and breastfeeding women. Planep Tablet can pass into breast milk, but its effect on the baby is unknown, so it is better to tell your doctor if you are taking Planep Tablet and breastfeeding. Dehydration with electrolyte and acid-base disturbances must be corrected before using Planep Tablet . Do not take extra potassium supplements or potassium-rich foods such as bananas and broccoli with Planep Tablet . It may lead to an excessive increase in blood potassium levels (hyperkalemia). Please take Planep Tablet at least 4 hours before sleeping to avoid frequent urination at night. Also, do not take Planep Tablet along with lithium to prevent serious side effects.

Drug-Drug Interactions

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EplerenoneItraconazole
Critical
EplerenoneSpironolactone
Critical

Drug-Drug Interactions

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EplerenoneItraconazole
Critical
How does the drug interact with Planep Tablet:
The blood levels and effects of Planep Tablet may be greatly increased when combined with itraconazole.

How to manage the interaction:
Although there is a possible interaction between Planep Tablet and Itraconazole, it is not recommended; they can be taken if prescribed by a doctor. Consult a doctor if you have complications such as hyperkalemia (high blood potassium), which in extreme circumstances can result in kidney problems, muscle paralysis, and an irregular heartbeat. Without first consulting your doctor, never stop taking medicines.
EplerenoneSpironolactone
Critical
How does the drug interact with Planep Tablet:
Combining Planep Tablet with Spiranolactone may significantly increase potassium levels in the blood which can lead to kidney issues and irregular heart rhythm.

How to manage the interaction:
Although there is a possible interaction between spironolactone and Planep Tablet, it is not recommended as it can lead to an interaction. You can take these medicines if prescribed by a doctor. Consult a doctor if you experience nausea, vomiting, weakness, confusion, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or an irregular heartbeat. It is essential to maintain proper fluid intake while taking these medications. Do not discontinue any medications without a doctor's advice.
EplerenoneClarithromycin
Critical
How does the drug interact with Planep Tablet:
Co-administration of Planep Tablet and Clarithromycin may significantly increase the blood levels and effects of Planep Tablet.This may increase the risk or severity of side effects like high blood potassium which can lead to kidney damage and irregular heart rate.

How to manage the interaction:
Taking Clarithromycin with Planep Tablet is not recommended as it can lead to interaction. However, it can be taken if a doctor advises it. If you experience any unusual symptoms like headaches, irritation, confusion, edema (swelling caused by too much fluid accumulation), weakness, palpitations, or constipation, consult a doctor immediately. Do not stop using any medications without the Doctor's advice.
EplerenonePosaconazole
Critical
How does the drug interact with Planep Tablet:
Coadministration of posaconazole with Planep Tablet can increase the blood levels of Planep Tablet. This can increase the risk of serious side effects, including hyperkalemia (high blood potassium).

How to manage the interaction:
Although there is an interaction between posaconazole and Planep Tablet, it can be taken if a doctor has advised it. However, if you experience any unusual symptoms contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
EplerenoneNefazodone
Critical
How does the drug interact with Planep Tablet:
Coadministration of Nefazodone with Planep Tablet can increase the levels of Planep Tablet in the body.

How to manage the interaction:
Taking Nefazodone with Planep Tablet together is not recommended as it can result in an interaction, but it can be taken if your doctor has advised it. However, if you notice any symptoms of headaches, irritation, confusion, edema (swelling caused by too much fluid accumulation), weakness, palpitations, or constipation, you should contact a doctor immediately. Do not stop using any medications without a doctor's advice.
EplerenoneRitonavir
Critical
How does the drug interact with Planep Tablet:
Co-administration of Planep Tablet and Ritonavir may significantly increase the blood levels of Planep Tablet.

How to manage the interaction:
Taking Ritonavir and Planep Tablet together is not recommended as it can lead to an interaction. However, it can be taken if a doctor advises it. If you experience any unusual symptoms like headaches, irritation, confusion, edema (swelling caused by too much fluid accumulation), weakness, palpitations, or constipation, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
EplerenonePotassium iodide
Critical
How does the drug interact with Planep Tablet:
Combining Planep Tablet with Potassium iodide may significantly increase potassium levels in the blood which can lead to kidney issues, muscle paralysis (loss of muscle function) and irregular heart rhythm.

How to manage the interaction:
Although there is a possible interaction between Potassium iodide and Planep Tablet, you can take these medicines if prescribed by a doctor. Consult a doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or irregular heartbeat. It is essential to maintain proper fluid intake while taking these medications. Do not discontinue any medications without a doctor's advice.
EplerenonePotassium citrate
Critical
How does the drug interact with Planep Tablet:
Taking Planep Tablet with Potassium citrate may significantly increase potassium levels in the blood which can lead to kidney issues, muscle paralysis (loss of muscle function) and irregular heart rhythm.

How to manage the interaction:
Although there is a possible interaction between Potassium citrate and Planep Tablet, you can take these medicines if prescribed by a doctor. Consult a doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or irregular heartbeat. It is essential to maintain proper fluid intake while taking these medications. Do not discontinue any medications without a doctor's advice.
EplerenoneSaquinavir
Critical
How does the drug interact with Planep Tablet:
Co-administration of EPELENONE and SAQUINAVIR may significantly increase the blood levels and side effects of Planep Tablet. This can increase the risk of serious side effects like high blood potassium, which in severe cases can lead to kidney failure, muscle paralysis (loss of muscle function) and irregular heart rhythm.

How to manage the interaction:
Taking saquinavir and Planep Tablet together is not recommended as it can lead to interaction. However, it can be taken if a doctor advises it. If you experience any unusual symptoms like headaches, irritation, confusion, edema (swelling caused by too much fluid accumulation), weakness, palpitations, or constipation, consult a doctor immediately. Do not stop using any medications without the doctor's advice.
EplerenoneKetoconazole
Critical
How does the drug interact with Planep Tablet:
Coadministration of Ketoconazole with Planep Tablet can increase the levels of blood potassium which can lead to kidney damage and irregular heart rate.

How to manage the interaction:
Taking ketoconazole with Planep Tablet is not recommended as it can result in an interaction, but it can be taken if a doctor has advised it. However, if you notice any symptoms of headaches, irritation, confusion, edema (swelling caused by too much fluid accumulation), weakness, palpitations, or constipation, you should contact a doctor immediately. Do not stop using any medications without the doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Consume antioxidant-rich food. Blueberries, cherries, tomatoes, squash, and bell peppers are highly antioxidants.
  • Eat natural diuretic foods. Asparagus, beets, green beans, grapes, onion, leafy greens, pineapple, leeks, pumpkin, and garlic are all-natural diuretic foods.
  • Use healthy cooking oils like soybean, olive, canola, and coconut oil.
  • You should avoid refined foods such as white bread, spaghetti, sugar, and red meat.
  • Reduce or eliminate Trans fatty acids, which are found in commercially baked items such as cookies, cakes, crackers, French fries, onion rings, doughnuts, and processed foods.
  • Avoid the consumption of too much salt or salty food.
  • Keep your weight under control with a BMI of 19.5-24.9.
  • Regular physical activity or exercise like walking improves your blood flow.
  • Elevate your legs or the swollen area on a chair or pillow.
  • Avoid standing or sitting for extended periods.
  • Avoid chronic stress, as it can raise your blood pressure.
  • Spend time with your loved ones to cope with stress and practice mindfulness techniques.
  • Quitting smoking and alcohol consumption is the best strategy to lower the risk of many health complications.

Habit Forming

No

Therapeutic Class

DIURETIC

Planep Tablet Substitute

Substitutes safety advice
  • Eptus 25 Tablet 15's

    by Others

    39.51per tablet
  • Planep 25 mg Tablet 15's

    by AYUR

    29.01per tablet
  • Eplehef 25 Tablet 10's

    by AYUR

    21.60per tablet
  • Eplebless 25 Tablet 10's

    by AYUR

    14.72per tablet
  • Epnone 25 Tablet 10's

    by AYUR

    23.49per tablet
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Alcohol

Unsafe

You are recommended not to consume alcohol along with Planep Tablet to avoid unpleasant side effects.

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Pregnancy

Caution

Planep Tablet should be used in pregnant women only if clinically needed, and the benefits outweigh the risks.

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Breast Feeding

Caution

Breast-feeding must be avoided during treatment with Planep Tablet . It is only if prescribed by a doctor and if the benefits outweigh the harms.

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Driving

Unsafe

It is not recommended to drive after taking Planep Tablet as it may occasionally cause drowsiness due to orthostatic hypotension (sudden drop in blood pressure on standing from lying position).

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Liver

Caution

Inform your doctor before receiving the Planep Tablet if you have a history of liver diseases/conditions. Your doctor may adjust your dose depending on your current kidney conditions.

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Kidney

Caution

Inform your doctor before receiving the Planep Tablet if you have a history of kidney diseases/conditions. Your doctor may adjust your dose depending on your current kidney conditions.

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Children

Caution

Planep Tablet is not recommended for children below 12 years of age.

FAQs

Planep Tablet is used to treat hypertension (high blood pressure) and oedema.

Planep Tablet works by increasing the amount of urine passed out from the kidneys. It effectively reduces excess fluid levels in the body. This reduces the heart's workload and makes the heart more efficient at pumping blood throughout the body. Thus, it also helps lower high blood pressure, reducing the chances of any future heart attack, stroke, or angina (chest pain) in the future.

It is not common, but Planep Tablet can sometimes increase blood sugar levels. Therefore, it is crucial to monitor your blood sugar level to check for any fluctuations. Also, the use of Planep Tablet should be avoided in patients with type 2 diabetes and some kidney problems.

Yes, Planep Tablet can cause increased potassium levels (hyperkalemia), especially in patients with kidney problems or if you are taking potassium supplements along with Planep Tablet . Please monitor your electrolyte level regularly to avoid increased blood potassium levels.

It is a medical term for fluid retention or overload. Due to oedema, the legs, hands, and other body parts start swelling, increasing blood pressure. If it does not subside, please consult your doctor immediately.

The main side effect of Planep Tablet is peeing (urination) more often than normal. Most people need to pee about 30 minutes after taking Planep Tablet and again within a few hours. Do not take Planep Tablet before going to bed, or you may have to wake up at night to go for urination frequently.

No, it is not recommended to take Planep Tablet along with lithium. It might increase lithium's level in the blood and lead to unpleasant side effects like visual impairment, loss of appetite, and muscle weakness. So, inform your doctor before starting Planep Tablet if you take lithium is recommended.

No, Planep Tablet is not a blood thinner. It is a diuretic used to treat high blood pressure and swelling.

Planep Tablet contains Eplerenone. It is an aldosterone antagonist type of potassium-sparing diuretic.

Planep Tablet may take up to 4 weeks to show its full effect. Keep taking Planep Tablet for the prescribed duration.

No, Planep Tablet is not known to cause erectile dysfunction. It does not have any effect on fertility.

Do not discontinue Planep Tablet without consulting the doctor. To treat your condition effectively, keep taking Planep Tablet for the prescribed duration.

Potassium-sparing diuretics increase urine production without depleting potassium reserves. Planep Tablet permits the body to lose sodium while retaining potassium. The amounts of potassium may rise as a result. Therefore, your doctor may regularly check your potassium levels.

Your doctor might have recommended Eplerenone instead of Losartan as a blood pressure medication because losartan may have been insufficient in lowering your blood pressure. However, Eplerenone increases the risk of elevated potassium levels, which may not be suitable for you. Hence, the doctor has prescribed Planep Tablet along with hydrochlorothiazide to prevent the rise in potassium levels.

Before starting Planep Tablet , let the doctor know if you are taking aspirin. Taking aspirin with Planep Tablet may decrease the effects of Planep Tablet . Contact your doctor if you experience signs of high blood pressure such as headache, blurred vision, trouble concentrating, or dizziness.

Side effects of Planep Tablet include dehydration, electrolyte disturbances (calcium, magnesium, and sodium), constipation, itching, and increased uric acid. If the side effects are persistent, reach out to your doctor.

Country of origin

India

Manufacturer/Marketer address

Lupin Ltd, 3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India Country of Origin: India
Other Info - PLA0042

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