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compositionComposition:FERRIC CARBOXYMALTOSE-50MG
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Prescription Medicine
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Revofer Injection is used to treat iron deficiency anaemia. It contains ferric carboxymaltose, which acts as a source of iron and helps in the transportation of oxygen throughout the body and the production of red blood cells. In some cases, this medicine may cause side effects such as nausea, flushing, dizziness, high blood pressure, and low levels of phosphorus in the blood. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy
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More about the Product

Composition :

FERRIC CARBOXYMALTOSE-50MG

Manufacturer/Marketer :

Lupin Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Revofer Injection

Revofer Injection is an injectable medicine used to treat iron deficiency anaemia in adults and certain pediatric patients. It is prescribed when oral iron supplements have not worked well or cannot be tolerated. The primary purpose of this treatment is to rapidly rebuild the body's iron stores and support red blood cell production.

Because this medicine is given as an injection or infusion into a vein, it is typically received in a clinic or hospital as a single or double-dose treatment rather than a daily routine. You do not need to fast before receiving your dose, so it can be given with or without food. Eating a diet rich in natural iron, such as green leafy vegetables and lean meats, can help support your long-term recovery.

Some patients may experience mild side effects, including headache, dizziness, or nausea. However, if you experience signs of a severe allergic reaction, such as breathing difficulties or swelling, or signs of low blood phosphate levels like muscle weakness, you must consult your doctor immediately.

Before starting your treatment, tell your doctor if you have kidney disease, high blood pressure, chronic infections, or a history of liver damage. Do not take this medicine if you have a known history of severe allergic reactions to iron injections, or if you have conditions associated with iron overload.

This injection can interfere with the absorption of oral iron pills, so you should not take oral iron supplements for at least five days after your dose. If you are pregnant, breastfeeding, or an elderly individual, consult your healthcare provider to discuss the benefits and potential risks of this therapy.

Uses of Revofer Injection

Your doctor may prescribe Revofer Injection to help manage the following conditions:

  • Iron deficiency anaemia: Restores low iron levels in the body when oral iron tablets are ineffective or cause severe stomach discomfort.
  • Iron deficiency in kidney disease: Replenishes vital iron stores in patients with non-dialysis-dependent chronic kidney disease to help manage anaemia.
  • Iron deficiency in heart failure: Helps improve iron levels in patients with chronic heart failure, which can improve physical capacity and overall quality of life.

Key Benefits

Revofer Injection is used to treat iron deficiency and iron deficiency anaemia when oral iron supplements are ineffective, not tolerated, or cannot be used. It rapidly replenishes the body's iron stores to support healthy red blood cell production.

  • Rapidly Replenishes Iron Stores: Delivers iron directly into the bloodstream, helping restore iron levels more quickly than oral iron supplements.
  • Treats Iron Deficiency Anaemia: Supports the production of healthy red blood cells, helping correct iron deficiency and improve haemoglobin levels.
  • Relieves Symptoms of Anaemia: Helps reduce symptoms such as tiredness, weakness, shortness of breath, dizziness, and reduced exercise tolerance associated with iron deficiency.
  • Suitable When Oral Iron Is Not Appropriate: Provides an effective treatment option for people who cannot tolerate oral iron or do not respond adequately to it.
  • Supports Recovery and Well-Being: Restoring healthy iron levels helps improve energy, physical performance, and overall quality of life.
Side effects of Revofer Injection 20 ml
Managing Medication-Triggered Flushing (Reddening of the skin): A Step-by-Step Guide:
  • Consult your doctor if you experience skin redness, itching, or irritation after taking medication.
  • Your doctor may adjust your treatment plan by changing your medication or providing guidance on managing your erythema symptoms.
  • Your doctor may recommend or prescribe certain medications to help alleviate symptoms.
  • Apply cool compresses or calamine lotion to the affected skin area to reduce redness and itching.
  • Stay hydrated by drinking plenty of water to help alleviate symptoms and keep your skin hydrated.
  • Monitor your skin condition closely and promptly report any changes, worsening symptoms, or concerns to your healthcare provider.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Here are the few steps for dealing with itching caused by drug use:
  • Report the itching to your doctor immediately; they may need to change your medication or dosage.
  • Use a cool, damp cloth on the itchy area to help soothe and calm the skin, reducing itching and inflammation.
  • Keep your skin hydrated and healthy with gentle, fragrance-free moisturizers.
  • Try not to scratch, as this can worsen the itching and irritate your skin.
  • If your doctor prescribes, you can take oral medications or apply topical creams or ointments to help relieve itching.
  • Track your itching symptoms and follow your doctor's guidance to adjust your treatment plan if needed. If the itching persists, consult your doctor for further advice.
  • Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.
  • Avoid trigger foods that can cause allergic reactions, such as nuts, shellfish, or dairy products.
  • Keep a food diary to track potential food allergens.
  • Include omega-3 rich foods like salmon and walnuts to reduce inflammation.
  • Wear loose, comfortable clothing made from soft fabrics like cotton.
  • Apply cool compresses or take cool baths to reduce itching.
  • Use gentle soaps and avoid harsh skin products.
  • Reduce stress through relaxation techniques like meditation or deep breathing.

Directions for Use

  • Your doctor will determine the dosage and timing of Revofer Injection based on your health condition. Typically, it is given once a week.
  • Revofer Injection will be administered by a qualified healthcare professional in a hospital setting.
  • Do not self-administer it.

How Revofer Injection Works

Revofer Injection contains ferric carboxymaltose. It is an iron replacement product that delivers iron directly to your body's cells. Once injected into a vein, the medicine gradually releases its iron content. Your bone marrow uses this iron to produce haemoglobin, the essential protein in red blood cells that carries oxygen from your lungs to the rest of your body. By delivering iron in a stable, controlled complex, the medicine allows your body to safely absorb and store the iron where it is needed most. This efficient process helps correct iron deficiency and anaemia much faster than traditional dietary changes or oral supplements.
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Alcohol

Caution

It is unknown if alcohol interacts with Revofer Injection, so please consult a doctor.

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Pregnancy

Caution

Consult your doctor if you are pregnant. Your doctor will decide if Revofer Injection can be taken during pregnancy or not.

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Breast Feeding

Caution

Consult your doctor if you are breastfeeding. Your doctor will decide if Revofer Injection can be taken by breastfeeding mothers or not.

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Driving

Safe if prescribed

Revofer Injection is unlikely to affect your ability to drive. However, drive or operate machinery only if you are alert.

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Liver

Caution

Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Revofer Injection is not recommended for children below 14 years as safety and effectiveness have not been established.

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Heart

Caution

Revofer Injection should be administered with caution in patients with heart problems. Please inform your doctor if you have any pre-existing heart problems before receiving Revofer Injection.

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Geriatrics

Caution

Revofer Injection should be administered with caution in elderly patients due to an increased risk of side effects. Seek medical advice if you have any concerns.

What if I have taken an overdose of Revofer Injection

Because this medicine is prepared and given by trained healthcare professionals in a controlled clinic or hospital, receiving an overdose is highly unlikely. However, if you suspect an issue or experience severe symptoms after your treatment, seek immediate medical attention.

Diet & Lifestyle Advise

  • Eat Iron-Rich Foods: Include foods such as lean meat, poultry, fish, beans, lentils, spinach, and iron-fortified cereals to help maintain healthy iron levels.
  • Increase Vitamin C Intake: Consume vitamin C-rich foods, such as citrus fruits, strawberries, tomatoes, broccoli, or bell peppers, with meals to improve iron absorption.
  • Avoid Iron Absorption Inhibitors During Meals: Limit tea, coffee, and dairy products around iron-rich meals, as they may reduce the absorption of dietary iron.
  • Stay Hydrated and Rest Well: Drink adequate fluids and get sufficient rest to support recovery and healthy red blood cell production.
health query

Have a query?

How Soon It Starts Working

The time required for Revofer Injection to start to work: The time required for Revofer Injection to show its action is unknown. The time for which the effects of Revofer Injection last: The duration of action for Revofer Injection is clinically unknown.

What if you forget to take Revofer Injection

If you miss an appointment to receive your injection, contact your healthcare provider's office immediately to reschedule. Since this medicine is administered by medical professionals, they will guide you on the safest way to adjust your schedule.

Storage

• Revofer Injection is stored at controlled room temperature, between 20°C and 25°C (68°F to 77°F).

Drug Warnings

  • Inspect the Medicine Before Administration: The solution should be dark brown and free from visible particles. Do not use it if it appears cloudy, discoloured, or damaged.
  • Remain Under Observation After Treatment: Stay at the healthcare facility for at least 30 minutes after your injection or infusion so you can be monitored for any allergic reactions.
  • Report Injection Site Reactions Immediately: Inform your doctor or nurse if you experience pain, burning, swelling, or leakage around the injection site during administration.
  • Attend Regular Blood Tests: Your doctor may monitor your haemoglobin, iron stores, and phosphate levels to assess your response to treatment and determine if additional doses are needed.
  • Inform Your Healthcare Provider About Other Medicines: Tell your doctor about all prescription medicines, over-the-counter products, vitamins, and herbal supplements you are taking before receiving Revofer Injection.

Drug-Drug Interactions

verifiedApollotooltip

Revofer Injection may interact with certain medicines, affecting their absorption or increasing the risk of side effects.

  • Oral iron supplements: Taking oral iron tablets concurrently with Revofer Injection can reduce the absorption of the oral iron. Your doctor will likely advise you to stop taking oral iron pills for at least five days after your injection.
FERRIC CARBOXYMALTOSEEnalapril
Severe
FERRIC CARBOXYMALTOSEDimercaprol
Severe

Drug-Drug Interactions

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FERRIC CARBOXYMALTOSEEnalapril
Severe
How does the drug interact with Revofer Injection 20 ml:
Taking Enalapril and Ferric Carboxymaltoside increases the side effects of enalapril.

How to manage the interaction:
Although taking Enalapril with Revofer Injection 20 ml may possibly result in an interaction, they can be taken together if prescribed by your doctor. However, if you experience dizziness, lightheadedness, headache, blurred vision, or chest pain, consult your doctor immediately. Do not discontinue any medications without consulting your doctor.
FERRIC CARBOXYMALTOSEDimercaprol
Severe
How does the drug interact with Revofer Injection 20 ml:
Coadministration of Dimercaprol with Revofer Injection 20 ml can increase the risk of developing kidney problems.

How to manage the interaction:
Although there is an interaction between Revofer Injection 20 ml and dimercaprol, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
  • No clinically significant food interactions are known with Revofer Injection when used as directed.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[IRON PREPARATIONS]

FAQs

Revofer Injection is used to treat iron deficiency anaemia in patients who are intolerant to oral iron preparations, have non-dialysis dependant chronic kidney disease, or require a quick build-up of iron stores.
Revofer Injection acts as a source of iron and helps in the transportation of oxygen throughout the body and the production of red blood cells. Thereby, Revofer Injection helps in treating anaemia.
Revofer Injection might cause hypophosphatemia (low phosphorus levels). Inform your doctor if you experience symptoms such as severe tiredness, bone or muscle pain, as these could be a sign of low phosphorus levels. Regular monitoring of phosphorus levels whilst on treatment with Revofer Injection is advised.
Consult your doctor if you have hypertension as Revofer Injection might cause high blood pressure, sometimes accompanied by dizziness, facial flushing, or nausea. Your doctor will monitor for signs and symptoms of hypertension while on treatment with Revofer Injection.
Revofer Injection might cause the stools to appear darker than usual; this is due to the elimination of unabsorbed iron. Do not worry, as it is normal and harmless. Consult a doctor if this bothers you or if you notice blood in your stools.
Oral iron preparations will be less effective when taken along with Revofer Injection. Inform your doctor if you are taking oral iron preparations or any supplements.
Iron deficiency anaemia occurs when the body's iron stores are too low to support the production of haemoglobin, a crucial protein in red blood cells that carries oxygen to the body's tissues. As a result, the body may not have enough healthy red blood cells or haemoglobin, leading to anaemia. Anaemia can cause symptoms like fatigue, weakness, pale skin, and shortness of breath.
Iron is a vital nutrient that can be sourced from a diverse range of foods. Animal-based options like red meat, poultry, and seafood are high in iron, with organ meats like liver and kidney being particularly rich. Plant-based sources include legumes like lentils, beans, and peas and leafy greens such as spinach, kale, and collard greens. Nuts and seeds like pumpkin, sesame, and sunflower are also good sources, along with fortified cereals and dried fruits like apricots, prunes, and raisins. Whole grains like quinoa, brown rice, and whole-wheat bread contain iron, too. Additionally, certain mushrooms like shiitake and oyster and cooked veggies like broccoli, Brussels sprouts, and sweet potatoes are iron-rich. Eating a varied diet that includes these foods can help ensure you meet your daily iron requirements.
Revofer Injection is usually safe to take during pregnancy. It's an iron supplement that helps with iron deficiency and anaemia, which are common in pregnant women. If you have any concerns, talk to your doctor. They'll check your needs and ensure the benefits outweigh any risks.
The duration of taking Revofer Injection depends on the individual's health condition and response to the medication. Always consult your healthcare provider for personalized advice on taking Revofer Injection. They will assess your needs and provide guidance on the appropriate duration of treatment.
Revofer Injection is a highly effective and well-tolerated iron supplement, particularly suited for individuals who struggle to absorb iron from food or have elevated iron requirements. However, talking to your healthcare provider before using Revofer Injection is essential. They will diagnose and confirm iron deficiency or anaemia, recommend the appropriate dosage and duration of treatment, and monitor your response to treatment, making adjustments as necessary. This ensures that you receive personalized care and optimal management of your iron levels.
To boost your iron levels, complement your iron supplement (Revofer Injection) with a balanced diet rich in iron-boosting foods. Opt for protein-rich options like red meat, poultry, and seafood, particularly shellfish and sardines. Legumes, including lentils, beans, and peas, are also packed with iron. Leafy greens like spinach, kale, collard greens, and broccoli are excellent choices. Pay attention to nuts and seeds like pumpkin seeds, sesame seeds, sunflower seeds, and whole grains like fortified cereals and quinoa. Dried fruits like apricots and prunes are also good sources of iron. Additionally, include a variety of cooked vegetables like bell peppers and sweet potatoes in your meals. Incorporating these iron-rich foods into your diet will support overall health and well-being.
You can take vitamin C/ Vitamin D/ multivitamin/ folic acid along with iron. In general, these vitamins do not cause any interactions, and they help in good iron absorption and healthy RBC. However, it's always a good idea to seek medical attention from a healthcare provider before starting any new supplement program to ensure it's appropriate for your specific health needs and to get proper guidance on usage.
Taking Revofer Injection with zinc may increase the risk of certain side effects. However, if it is essential to use together, your doctor may change the dose or how often you use one or both of the medicines.
There are no documented interactions between Revofer Injection and Tylenol (acetaminophen), but it is recommended that you inform your doctor before using them together to guarantee safety and prevent negative complications.
Taking Revofer Injection does not typically lead to weight gain. However, as your anaemia improves, you may experience weight fluctuations. If you notice any unexpected changes in your body weight during treatment, consult your doctor to discuss potential causes and appropriate guidance.
Causing constipation is the most common side effect of the Revofer Injection (especially in breastfeeding women if the doctor advises to use it). However, Revofer Injection is not typically linked to acne development. If you experience worsening constipation or unexpected acne, consult your healthcare provider for personalized advice and management.
The common side effects of Revofer Injection are nausea, flushing, dizziness, high blood pressure, Low levels of phosphorus in the blood, and some injection site reactions. However, these symptoms vanish as your body adjusts to the medication. If these symptoms become worse, please consult a doctor for relief.
Revofer Injection is generally considered safe when following the instructions recommended by a doctor. However, like all medications, it can have side effects and potential interactions with other drugs. It's important to inform them of any pre-existing and existing medical conditions or medication history to avoid negative complications.
No, fasting is not required before receiving this medicine. You can eat and drink normally on the day of your appointment. Talk to your doctor or pharmacist if you have any questions about preparing for your infusion.
The number of doses depends entirely on your weight, your current iron levels, and your doctor's assessment. Some patients require only a single dose, while others may receive two doses given at least seven days apart. Talk to your doctor or pharmacist to understand your specific treatment plan.
Some individuals may feel slightly dizzy or lightheaded after receiving this injection. It is recommended to see how you feel during your 30-minute post-injection observation period before deciding to drive. Talk to your doctor or pharmacist if you feel unwell or dizzy.
If the iron solution leaks out of the vein into the surrounding skin during the infusion, it can cause long-lasting or permanent brown discolouration. Tell your healthcare provider immediately if you feel pain or notice swelling during the injection. Talk to your doctor or pharmacist if you notice persistent discolouration after your treatment.
There is no direct interaction between alcohol and Revofer Injection. However, drinking alcohol can sometimes worsen side effects like dizziness or lightheadedness. It is generally best to avoid alcohol immediately after your injection. Talk to your doctor or pharmacist for advice.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

Lupin Ltd, 3Rd Floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India.
Other Info - REV0905

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