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  3. Sameo 400 mg Tablet 10's

Sameo 400 mg Tablet 10's, Pack of 10 TabletS
Sameo 400 mg Tablet 10's, Pack of 10 TabletS
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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Sameo 400mg Tablet is an amino acid used in the treatment of mild to moderate alcoholic liver disease, osteoarthritis, and depression. This medicine helps in optimal cellular functioning, monitors and regulates important physiological functions, increases glutathione concentration and metabolism of the liver. Common side effects include nausea, diarrhoea, stomach pain, and flatulence.
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Composition :

S ADENOSYL L METHIONINE-400MG

Manufacturer/Marketer :

Feron Health Care Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Sameo 400mg Tablet

Sameo 400mg Tablet is used in the treatment of mild to moderate alcoholic liver disease, osteoarthritis, and depression. Alcoholic liver disease occurs due to liver damage because of excessive alcohol consumption. Osteoarthritis is a condition in which the joints are affected. Depression is a mood disorder and a psychological, physiological and emotional experience that affects the way we think, the things we do and the way we act.

Sameo 400mg Tablet contains S-Adenosyl-L-Methionine, an essential amino acid required for optimal cellular functioning. Sameo 400mg Tablet is believed to monitor and regulate important physiological functions in living cells. It increases glutathione concentration and metabolism of the liver. Sameo 400mg Tablet increases chondrocyte proteoglycan synthesis, thereby helping treat osteoarthritis.

Sameo 400mg Tablet may be taken with or without food, but it is better to take it at a designated time. Sameo 400mg Tablet should be swallowed whole and not crushed or chewed. In some cases, Sameo 400mg Tablet may cause certain common side effects such as nausea, diarrhoea, stomach pain, and flatulence. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if these side effects persist. 

It is advisable to inform the doctor if you are allergic to any of the components of Sameo 400mg Tablet . Consult your doctor if you are pregnant, planning to get pregnant, or breastfeeding. Exercise caution when taking Sameo 400mg Tablet with any anti-Parkinsonian drugs or anti-depressants. It is not advisable to take alcohol with Sameo 400mg Tablet as there may be an interaction. Discuss your entire surgical history with your treating doctor and keep them informed of any pending surgical procedure.

Uses of Sameo 400mg Tablet

Treatment of Liver disease, osteoarthritis and depression.

Directions for Use

• Sameo 400mg Tablet can be taken with or without food as advised by the doctor.• Adhere to your doctor's guidance regarding the dosage and timing of this medication for optimal effectiveness.• Swallow Sameo 400mg Tablet as a whole with a glass of water.• Do not crush, chew, or break it.

Medicinal Benefits

Sameo 400mg Tablet contains S-Adenosyl-L-Methionine. Sameo 400mg Tablet helps in the synthesis of essential amino acid methionine, which is required for major body functions. It helps provide cellular energy and charge the living cells of various organs like the brain, bones and liver with stamina and fuel, thereby finding application in the treatment of depression, arthritis and liver disease. It helps in major detoxification of the liver in case of diseases caused by a retarded flow of bile such as intrahepatic cholestasis. Sameo 400mg Tablet may also find use in the treatment of fibromyalgia, chronic pain, attention deficit hyperkinetic disorder and Alzheimer’s disease. However, studies to understand the mechanism behind the same have been inconclusive.

How Sameo 400mg Tablet Works

Sameo 400mg Tablet contains S-Adenosyl-L-Methionine, an essential amino acid required for optimal cellular functioning. Sameo 400mg Tablet is believed to monitor and regulate important physiological functions in living cells. It increases glutathione concentration and metabolism of the liver. Sameo 400mg Tablet increases chondrocyte proteoglycan synthesis, thereby helping treat osteoarthritis.

Storage

Store in a cool and dry place away from sunlight
Side effects of Sameo 400 mg Tablet
Managing Medication-Related Skin Allergies: A Step-by-Step Guide
  • If you experience signs of skin allergies such as redness, itching, or irritation after taking medication, contact your doctor right away.
  • To alleviate skin allergy symptoms, your doctor may change your medication regimen or offer tailored medication management advice.
  • Your doctor may recommend or prescribe drugs to relieve discomfort.
  • Cool compresses or calamine lotion can help relieve redness and itching on the afflicted skin area.
  • Staying hydrated by consuming plenty of water can help relieve discomfort.
  • Monitor your skin condition closely and promptly report any changes, worsening symptoms, or concerns to your healthcare provider.
Here are the steps to manage the medication-triggered Tachycardia (Fast Heart Rate):
  • Contact your doctor immediately if you're experiencing a fast heart rate, palpitations, or other heart-related symptoms. This is crucial to determine whether the symptoms are related to your medication.
  • Your doctor may need to adjust your medication regimen to alleviate the fast heart rate symptoms. This could involve changing the medication, reducing the dosage, or adding new medications to counteract the side effects.
  • Follow your doctor's advice on monitoring your heart rate and blood pressure. This will help track any changes and ensure your heart rate returns normal.
  • If you experience severe symptoms such as chest pain, dizziness, or shortness of breath, seek immediate medical attention. These symptoms can indicate a more serious condition that requires prompt treatment.
  • Exercising regularly helps lower the risk of heart problems.
  • Maintain a healthy diet, including vegetables and fruits.
  • Rest well; get enough sleep.
  • Manage stress with yoga and meditation.
  • Limit alcohol and smoking.
  • Swelling of the throat can worsen if there is no proper rest for your throat.
  • Drink plenty of warm fluids and frequently gargle with salt water.
  • Humidify the surrounding air using a humidifier, as dry air may increase dryness and throat pain.
  • Talk to your doctor if the swelling bothers you while swallowing food.
  • Take enough rest and stay in warm places to reduce pain quickly.
Here are the seven steps to manage medication-triggered Dyspnea (Difficulty Breathing or Shortness of Breath):
  • Tell your doctor immediately if you experience shortness of breath after taking medication.
  • Your doctor may adjust the medication regimen or dosage or give alternative medical procedures to minimize the symptoms of shortness of breath.
  • Monitor your oxygen levels and breathing rate regularly to track changes and potential side effects.
  • For controlling stress and anxiety, try relaxation techniques like deep breathing exercises, meditation, or yoga.
  • Make lifestyle changes, such as quitting smoking, exercising regularly, and maintaining a healthy weight.
  • Seek emergency medical attention if you experience severe shortness of breath, chest pain, or difficulty speaking.
  • Follow up regularly with your doctor to monitor progress, adjust treatment plans, and address any concerns or questions.
Managing back pain as a side effect of medication requires a combination of self-care techniques, lifestyle modifications, and medical interventions. Here are the steps:
  • Talk to your doctor about your back pain and potential medication substitutes or dose changes.
  • Try yoga or Pilates and other mild stretching exercises to increase flexibility and strengthen your back muscles.
  • To lessen the tension on your back, sit and stand upright and maintain proper posture.
  • To alleviate discomfort and minimize inflammation, apply heat or cold packs to the afflicted area.
  • Under your doctor's supervision, think about taking over-the-counter painkillers like acetaminophen or ibuprofen.
  • Make ergonomic adjustments to your workspace and daily activities to reduce strain on your back.
  • To handle tension that could make back pain worse, try stress-reduction methods like deep breathing or meditation.
  • Use pillows and a supportive mattress to keep your spine in the right posture as you sleep.
  • Back discomfort can worsen by bending, twisting, and heavy lifting.
  • Speak with a physical therapist to create a customized training regimen to increase back strength and flexibility.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.

What if I have taken an overdose of Sameo 400mg Tablet

Do not take more than the suggested dose of Sameo 400mg Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

It is advisable to inform the doctor if you are allergic to any of the components of Sameo 400mg Tablet . Keep your doctor informed of your entire medical history before using Sameo 400mg Tablet . Consult your doctor if you are pregnant, planning to get pregnant, or breastfeeding. Exercise caution when taking Sameo 400mg Tablet with any anti-Parkinsonian drugs or anti-depressants. It is not advisable to take Sameo 400mg Tablet with alcohol as there may be an interaction. Discuss your entire surgical history with your treating doctor and keep them informed of any pending surgical procedure.

Drug-Drug Interactions

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No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

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Diet & Lifestyle Advise

  • Load up on lean meats, fatty fish, green leafy vegetables, fruits and nuts to enhance anti-oxidation and optimal functioning of the body.

  • Drink a lot of water and keep yourself hydrated.
  • Maintain a healthy weight by exercising for at least 30 minutes daily. 
  • Stop smoking as this can have a negative effect on the absorption of Sameo 400mg Tablet and worsen the disease conditions.

Habit Forming

No

Therapeutic Class

MISCELLANEOUS

Sameo 400mg Tablet Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Caution

It is not known whether it is safe to consume alcohol with Sameo 400mg Tablet . Please consult your doctor if you have any concerns.

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Pregnancy

Caution

Sameo 400mg Tablet should be used with caution in pregnant women. Please consult a doctor if you are pregnant.

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Breast Feeding

Caution

Sameo 400mg Tablet should be used with caution in nursing mothers. Please consult a doctor.

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Driving

Caution

Sameo 400mg Tablet may rarely cause drowsiness and dizziness. Exercise caution while driving in case of these side effects.

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Liver

Consult your doctor

Sameo 400mg Tablet is possibly safe on the liver. Please consult your doctor in case of any concerns.

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Kidney

Consult your doctor

Sameo 400mg Tablet is possibly safe on the kidney. Please consult your doctor in case of any concerns.

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Children

Caution

It is not established if Sameo 400mg Tablet is safe to use in children. Please consult the treating doctor in case of any concerns.

Have a query?

FAQs

Sameo 400mg Tablet is used in the treatment of mild to moderate alcoholic liver disease, osteoarthritis, and depression.

Please see an orthopaedic doctor if you have had a fracture. Sameo 400mg Tablet is used in the case of arthritis and has limited use in the treatment of fractures as a fracture is more of surgical concern.

Yes, Sameo 400mg Tablet finds a lot of benefit in treating depression. However, if you are on any anti-depressants, keep your doctor informed to avoid any interactions.

In case you miss a dose of Sameo 400mg Tablet , take it as soon as possible. However, if it is too close to the next dose, revert to the original schedule.

Sameo 400mg Tablet is probably safe on the kidney; however, in case of CKD, it is best to consult your treating doctor before using Sameo 400mg Tablet .

Sameo 400mg Tablet works by the synthesis of methionine, which is an essential amino acid required for cellular energy.

Sameo 400mg Tablet may cause side effects such as nausea, diarrhoea, stomach pain, and flatulence. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if these side effects persist.

Sameo 400mg Tablet should not be used by people who are allergic to any of its components. It is also not recommended for people with bipolar disorder, HIV, pregnant and nursing women.

Sameo 400mg Tablet contains S-Adenosylmethionine, a naturally occurring compound found in almost every tissue and fluid in the body. It is made in the body from methionine, an amino acid found in foods.

It is unknown if Sameo 400mg Tablet is safe to use for the long term. Take Sameo 400mg Tablet for the duration suggested by the doctor.

Country of origin

India

Manufacturer/Marketer address

1-20-268/G3,KM White House,Opp Hockey Stadium,Rasoolpura Road BEGUMPET,HYDERABAD-500003,TELANGANA,INDIA
Other Info - SAM0124

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Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 6:57 AM IST

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Reference

  1. https://www.webmd.com/vitamins/ai/ingredientmono-786/same
  2. https://www.drugs.com/npp/same.html
  3. https://www.nccih.nih.gov/health/sadenosyllmethionine-same-in-depth

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