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  3. Stamlo Trio 80/6.25 Tablet 15's

Stamlo Trio 80/6.25 Tablet 15's, Pack of 15
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Stamlo Trio 80/6.25 Tablet is used to treat high blood pressure (hypertension). It widens blood vessels and increases blood flow, further improving the oxygen delivery to the heart tissue. Also, it decreases the amount of blood the heart pumps (cardiac output) and reduces body fluids outside the cells. It lowers blood pressure and increases blood flow by preventing the narrowing of blood vessels. It may cause side effects such as sleepiness, taste changes, ankle swelling, headache, flushing (feeling warmth in the face, ears, neck, and trunk), dizziness, tiredness, irregular heartbeat, and upset stomach. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Composition :

AMLODIPINE-5MG + CHLORTHALIDONE-12.5MG + TELMISARTAN-80MG

Manufacturer/Marketer :

Dr Reddy's Laboratories Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Stamlo Trio 80/6.25 Tablet

Stamlo Trio 80/6.25 Tablet is an anti-hypertensive drug primarily used to treat high blood pressure (hypertension). Hypertension is a medical condition in which blood pressure is elevated persistently in the arteries. It is considered an essential risk factor for cardiovascular diseases. 

Stamlo Trio 80/6.25 Tablet consists of three anti-hypertensive medicines, Amlodipine, Chlorthalidone, and Telmisartan. Amlodipine belongs to the class of calcium channel blockers. It is a vasodilator that dilates (widens) blood vessels and increases blood flow, further improving the oxygen delivery to the heart tissue. Chlorthalidone belongs to the class of diuretics (water pills) with antihypertensive activity. It inhibits sodium and chloride reabsorption from absorbing excess salts that cause fluid retention or build-up. Chlorthalidone lowers blood pressure by decreasing the amount of blood the heart pumps (cardiac output) and reducing plasma and extracellular fluid volume (body fluids outside the cells). Telmisartan belongs to a group of drugs called angiotensin II receptor antagonists (angiotensin is a hormone that constricts blood vessels and increases blood pressure). It lowers blood pressure and increases blood flow by preventing the narrowing of blood vessels. 

In some cases, Stamlo Trio 80/6.25 Tablet can cause side effects like sleepiness, taste changes, ankle swelling, headache, flushing (feeling warmth in the face, ears, neck, and trunk), dizziness, tiredness, palpitations (irregular heartbeat), and upset stomach. Most of these side effects of Stamlo Trio 80/6.25 Tablet do not require medical attention and gradually resolve over time. However, if these side effects persist longer, please consult your doctor.

If you are known to be allergic to Stamlo Trio 80/6.25 Tablet or any other medicines, please inform your doctor. Before taking Stamlo Trio 80/6.25 Tablet , let your doctor know if you have any heart, kidney, or liver problems, diabetes, electrolyte imbalance, and dehydration. Avoid potassium supplements with Stamlo Trio 80/6.25 Tablet as it may lead to high potassium levels in the blood. Pregnant or breastfeeding women should also consult their doctor before taking Stamlo Trio 80/6.25 Tablet . It is advised to complete the prescribed course, even if you feel better. Please do not stop taking Stamlo Trio 80/6.25 Tablet on your own, as it may lead to the recurrence of symptoms or worsen the disease. Do not consume alcohol with Stamlo Trio 80/6.25 Tablet as it may increase the risk of low blood pressure.

Uses of Stamlo Trio 80/6.25 Tablet

Treatment of Hypertension (high blood pressure).

Directions for Use

• Stamlo Trio 80/6.25 Tablet can be taken with or without food, but taking it with food may reduce stomach upset.• It is advised to take Stamlo Trio 80/6.25 Tablet once daily or as directed by your doctor, at the same time each day for best results.• Swallow Stamlo Trio 80/6.25 Tablet as a whole with a glass of water.• Do not crush, chew, or break it.

Medicinal Benefits

Stamlo Trio 80/6.25 Tablet is an anti-hypertensive drug that treats high blood pressure (hypertension). It contains Amlodipine, Chlorthalidone, and Telmisartan. Amlodipine is a calcium channel blocker that dilates (widens) blood vessels and increases blood flow. It is used to treat high blood pressure, chest pain (angina), and other conditions caused by coronary artery disease. Chlorthalidone is a diuretic (water pill). It prevents the body from absorbing excess salts that cause fluid retention or build-up. It effectively treats high blood pressure, fluid retention in patients with congestive heart failure, cirrhosis (chronic damage) of the liver, kidney disorders, or edema caused by steroids or estrogen therapy. Telmisartan is an angiotensin II receptor antagonist (angiotensin is a hormone that constricts blood vessels and increases blood pressure). It lowers blood pressure and increases blood flow by preventing the narrowing of blood vessels. It reduces the risk of stroke, heart attack, or death from heart problems.

How Stamlo Trio 80/6.25 Tablet Works

Stamlo Trio 80/6.25 Tablet consists of three anti-hypertensive medicines, Amlodipine, Chlorthalidone, and Telmisartan. Amlodipine belongs to the class of calcium channel blockers. It is a vasodilator that dilates (widens) blood vessels and increases blood flow, further improving the oxygen delivery to the heart tissue. Chlorthalidone belongs to the class of diuretics (water pills) with antihypertensive activity. It inhibits sodium and chloride reabsorption from absorbing excess salts that cause fluid retention or build-up. Chlorthalidone lowers blood pressure by decreasing the amount of blood the heart pumps (cardiac output) and reducing plasma and extracellular fluid volume (body fluids outside the cells). Telmisartan belongs to a group of drugs called angiotensin II receptor antagonists (angiotensin is a hormone that constricts blood vessels and increases blood pressure). It lowers blood pressure and increases blood flow by preventing the narrowing of blood vessels.

Storage

Keep out of sight and reach of children.
Side effects of Stamlo Trio 80/6.25 Tablet
  • Eat smaller meals and chew food thoroughly.
  • Try foods with softer textures.
  • If you have difficulty swallowing liquids, use thickener.
  • Learn new swallowing techniques from a speech and language therapist.
  • Avoid alcohol and caffeine as these may dry your throat and mouth making it more difficult to swallow.
  • Consider alternative forms of feeding, such as feeding tubes through nose or a hole into your stomach.
  • Talk to your doctor about oral potassium supplements.
  • Eat potassium rich foods such as bananas, avocados, oranges, dark leafy greens, beans and peas, fish, spinach, milk and tomatoes.
  • Limit intake of full-fat dairy products, red meat and processed foods rich in saturated fats.
  • Avoid foods with label “partially hydrogenated oils”.
  • Eat more vegetables, fruits, oats, whole grains, lentils and beans to increase fiber intake.
  • Include foods rich in monounsaturated fats like nuts, avocados, olive oil, and oily fish.
  • Limit consumption of egg yolks.
  • Exercise for at least 30 minutes 5 days a week.
  • Aim for weight loss and maintain healthy weight.
  • Quit smoking as smoking raises the risk of heart disease associated with cholesterol.
  • Limit alcohol consumption as excessive drinking may raise cholesterol levels.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
  • Avoid triggers like alcohol, caffeine, and energy drinks.
  • Try relaxation techniques such as yoga, meditation, or deep breathing.
  • Exercise regularly as it helps maintain heart health.
  • Follow a nutritious and balanced diet.

What if I have taken an overdose of Stamlo Trio 80/6.25 Tablet

Do not take more than the prescribed dose of Stamlo Trio 80/6.25 Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Monitor your blood pressure levels regularly. If you are known to be allergic to Stamlo Trio 80/6.25 Tablet or have any kidney or liver problems or severe dehydration, please inform your doctor beforehand. Brief your medical history if you have low blood pressure, diabetes, gout, lupus (immune system disorder), hyperkalemia (high potassium levels), heart diseases (aortic stenosis, heart failure), angioedema (swelling of the lower layer of skin and tissue), anuria (low or no urine output), and asthma before starting Stamlo Trio 80/6.25 Tablet . Avoid potassium supplements with Stamlo Trio 80/6.25 Tablet as it may lead to high potassium levels in the blood. Too much sweating, diarrhea, or vomiting while using Stamlo Trio 80/6.25 Tablet may lead to dehydration; hence it is advised to drink enough fluids. Stamlo Trio 80/6.25 Tablet can affect and harm the developing baby during pregnancy. Consult your doctor before using Stamlo Trio 80/6.25 Tablet if you are a pregnant or breastfeeding mother. Complete the course strictly as suggested by the doctor, even if you feel better, to avoid disease recurrence. Avoid consumption of alcohol with Stamlo Trio 80/6.25 Tablet as it may increase the risk of low blood pressure. Safety and effectiveness of Stamlo Trio 80/6.25 Tablet in pediatric patients have not been established.

Drug-Drug Interactions

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AmlodipineDantrolene
Critical
TelmisartanAliskiren
Critical

Drug-Drug Interactions

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AmlodipineDantrolene
Critical
How does the drug interact with Stamlo Trio 80/6.25 Tablet:
Using Stamlo Trio 80/6.25 Tablet together with dantrolene may increase the risk of hyperkalemia (high blood potassium).

How to manage the interaction:
Taking Stamlo Trio 80/6.25 Tablet with Dantrolene can cause an interaction, consult a doctor before taking it. You should seek medical attention if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
TelmisartanAliskiren
Critical
How does the drug interact with Stamlo Trio 80/6.25 Tablet:
Co-administration of Aliskiren with Stamlo Trio 80/6.25 Tablet can increase the risk of hyperkalemia (high potassium levels in the blood).

How to manage the interaction:
Taking Stamlo Trio 80/6.25 Tablet with Aliskiren can possibly lead to an interaction, please consult a doctor before taking it. Do not discontinue the medications without consulting a doctor.
chlorthalidoneCisapride
Critical
How does the drug interact with Stamlo Trio 80/6.25 Tablet:
Co-administration of Stamlo Trio 80/6.25 Tablet and cisapride may increase the risk or severity of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Stamlo Trio 80/6.25 Tablet with Cisapride is not recommended, please consult your doctor before taking it. Do not discontinue the medication without consulting a doctor.
AmlodipinePrimidone
Severe
How does the drug interact with Stamlo Trio 80/6.25 Tablet:
Using Stamlo Trio 80/6.25 Tablet and primidone together may lower Stamlo Trio 80/6.25 Tablet blood levels, which makes the medicine less effective.

How to manage the interaction:
Although co-administration of Stamlo Trio 80/6.25 Tablet with primidone can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
AmlodipineRifabutin
Severe
How does the drug interact with Stamlo Trio 80/6.25 Tablet:
Using Stamlo Trio 80/6.25 Tablet and rifabutin together may lower Stamlo Trio 80/6.25 Tablet blood levels, which makes the medicine less effective.

How to manage the interaction:
Although there is an interaction between Stamlo Trio 80/6.25 Tablet with rifabutin, but it can be taken if a doctor has advised it. Consult the doctor if you experience any unusual symptoms. Do not discontinue any medications without consulting a doctor.
AmlodipineSimvastatin
Severe
How does the drug interact with Stamlo Trio 80/6.25 Tablet:
Taking simvastatin with Stamlo Trio 80/6.25 Tablet may result in considerably higher blood levels of simvastatin and may increase the risk of side effects (liver damage and rhabdomyolysis - an uncommon but serious illness characterized by the breakdown of skeletal muscle tissue).

How to manage the interaction:
Although taking Stamlo Trio 80/6.25 Tablet with simvastatin can result in an interaction, it can be taken if a doctor has advised it. If you have unexplained muscular pain, soreness, or weakness while using simvastatin, especially if these symptoms are accompanied by fever or dark-colored urine, consult the doctor immediately. However, if you develop a fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, and/or yellowing of the skin or eyes, consult the doctor. Do not stop using any medications without a doctor's advice.
AmlodipineTizanidine
Severe
How does the drug interact with Stamlo Trio 80/6.25 Tablet:
Co-administration of Tizanidine and Stamlo Trio 80/6.25 Tablet can increase the risk or severity of developing side effects like low blood pressure.

How to manage the interaction:
Although co-administration of Stamlo Trio 80/6.25 Tablet with tizanidine can result in an interaction, it can be taken when a doctor has advised it. However, if you experience headache, dizziness, palpitations, or irregular heart rate while taking these drugs, contact the doctor immediately. Use caution while getting up from a sitting or sleeping position and avoid driving or using dangerous machinery. Do not discontinue any medications without consulting the doctor.
AmlodipineNitisinone
Severe
How does the drug interact with Stamlo Trio 80/6.25 Tablet:
Coadministration of Stamlo Trio 80/6.25 Tablet and Nitisinone may increase the blood levels and effects of Nitisinone.

How to manage the interaction:
Taking Nitisinone with Stamlo Trio 80/6.25 Tablet together can result in an interaction, but it can be taken if a doctor has advised it. If you notice any of these symptoms or if you feel unwell after taking your medication, it's important to contact a doctor right away. Do not stop using any medications without a doctor's advice.
AmlodipineCarbamazepine
Severe
How does the drug interact with Stamlo Trio 80/6.25 Tablet:
Coadministration of Stamlo Trio 80/6.25 Tablet and carbamazepine together may significantly reduce Stamlo Trio 80/6.25 Tablet blood levels, making the medicine less effective.

How to manage the interaction:
Although there is an interaction between Stamlo Trio 80/6.25 Tablet with carbamazepine, it can be taken if a doctor has advised it. However, if you experience any unusual symptoms contact the doctor immediately. Do not stop using any medications without talking to a doctor.
AmlodipineSirolimus
Severe
How does the drug interact with Stamlo Trio 80/6.25 Tablet:
Co-administration of Stamlo Trio 80/6.25 Tablet can make Sirolimus may increase the risk of angioedema (a condition associated with swelling of the face, eyes, lips, tongue, throat, and occasionally also the hands and feet).

How to manage the interaction:
There may be a possibility of interaction between Stamlo Trio 80/6.25 Tablet and Sirolimus, but it can be taken if prescribed by a doctor. However, consult the doctor if you notice any swelling of the face, eyes, lips, tongue, throat, hands and feet or have trouble breathing or swallowing. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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AMLODIPINE-5MG+CHLORTHALIDONE-12.5MG+TELMISARTAN-80MGPotassium rich foods
Moderate

Drug-Food Interactions

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AMLODIPINE-5MG+CHLORTHALIDONE-12.5MG+TELMISARTAN-80MGPotassium rich foods
Moderate
Common Foods to Avoid:
Lentils, Orange Juice, Oranges, Raisins, Potatoes, Salmon Dried, Spinach, Tomatoes, Sweet Potatoes, Coconut Water, Beans, Beetroot, Broccoli, Bananas, Apricots, Avocado, Yogurt

How to manage the interaction:
Taking potassium rich food while on the treatment with Amlodipine, chlorthalidone and telmisartan can increase the levels of potassium salt in blood which lead to experience nausea, vomiting, weakness, confusion, tingling in hands or feet, feeling of heaviness in the legs, or slow or rapid heartbeat. Avoid or limit taking potassium rich food while on the treatment with Amlodipine, chlorthalidone and telmisartan.

Diet & Lifestyle Advise

  • Reduce sodium intake in your diet to maintain your blood pressure.

  • Eat natural and healthy foods by cutting down on high on sodium processed foods.

  • Lose those extra pounds since being obese can be a risk factor for hypertension.

  • Exercise regularly to maintain good heart health.

  • Avoid smoking and alcohol intake.

  • Chronic stress may also cause high blood pressure. Therefore, avoid stress triggers and make time for yourself to relax and do activities that you enjoy.

  • Try to include heart-healthy omega-3 fatty acids-containing food drinks in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil, and coconut oil to lower your elevated blood pressure.

  • Limit sodium chloride intake (table salt) in your daily diet to 2300 mg per day or less than 1500 mg is ideal for most adults.

Habit Forming

No

Therapeutic Class

ANTI- HYPERTENSIVES

Stamlo Trio 80/6.25 Tablet Substitute

Substitutes safety advice

Product Substitutes

bannner image

Alcohol

Unsafe

It is unsafe to consume alcohol since alcohol consumption with Stamlo Trio 80/6.25 Tablet may increase the risk of low blood pressure and cause adverse effects, such as dizziness, fainting, light-headedness, or headache.

bannner image

Pregnancy

Unsafe

Stamlo Trio 80/6.25 Tablet is not recommended and unsafe in pregnancy. It can affect and harm the developing baby. Consult your doctor before taking Stamlo Trio 80/6.25 Tablet if you plan to become pregnant or already pregnant. Your doctor will weigh the potential risks and benefits before prescribing Stamlo Trio 80/6.25 Tablet .

bannner image

Breast Feeding

Caution

There is no evidence on how Stamlo Trio 80/6.25 Tablet affects breastfeeding. Please consult your doctor before taking Stamlo Trio 80/6.25 Tablet if you are breastfeeding.

bannner image

Driving

Caution

Stamlo Trio 80/6.25 Tablet may cause side effects like dizziness, headaches, nausea, or tiredness, which can affect your ability to concentrate and drive. Hence, it is recommended not to drive or operate machinery until you are mentally alert.

bannner image

Liver

Caution

Let your doctor know if you have any history of liver diseases before taking Stamlo Trio 80/6.25 Tablet . The dosage will be initiated in lower doses and will be further increased in patients with liver diseases. However, Stamlo Trio 80/6.25 Tablet is not recommended in patients with severe hepatic impairment.

bannner image

Kidney

Caution

Stamlo Trio 80/6.25 Tablet may affect kidney functioning. Hence it is advised to seek doctor advice before starting Stamlo Trio 80/6.25 Tablet if you have kidney problems. However, it is not recommended in patients with severe renal impairment.

bannner image

Children

Unsafe

Safety and effectiveness of Stamlo Trio 80/6.25 Tablet in pediatric patients have not been established.

Have a query?

FAQs

Stamlo Trio 80/6.25 Tablet belongs to the anti-hypertensive drugs class, primarily used to treat high blood pressure (hypertension).

Stamlo Trio 80/6.25 Tablet consists of anti-hypertensive/ blood pressure-lowering drugs: Amlodipine, Chlorthalidone, and Telmisartan. These medicines collectively lower the blood pressure by preventing the fluid build-up and widening the blood vessels, thus improving the blood supply and oxygen delivery to the heart.

Yes, Stamlo Trio 80/6.25 Tablet can make you feel dizzy. Dizziness usually occurs when you suddenly stand up from a lying or sitting position. Try rising slowly when you change your posture to relieve dizziness. If the side effect persists longer, please seek medical help.

Stamlo Trio 80/6.25 Tablet may cause ankle swelling upon long-term use. Please try to keep your feet at elevated levels when sitting for long hours or sleeping. If the problem persists, consult your doctor and do as advised.

Stamlo Trio 80/6.25 Tablet can cause high potassium levels in the blood leading to hyperkalemia (high potassium levels in the blood). Hence it is not recommended to use potassium supplements along with Stamlo Trio 80/6.25 Tablet . However, consult your doctor if you are already taking other medicines before starting Stamlo Trio 80/6.25 Tablet .

Do not stop using Stamlo Trio 80/6.25 Tablet even if you feel better. It should be strictly used as advised by your doctor to avoid the recurrence of symptoms and worsening of the disease.

Please inform your doctor if you are taking Stamlo Trio 80/6.25 Tablet and need to undergo any surgery. Your doctor may ask you to stop using Stamlo Trio 80/6.25 Tablet or prescribe any alternate medication because blood pressure may be further lowered if taken along with general anesthesia.

Stamlo Trio 80/6.25 Tablet is not recommended and unsafe in pregnancy. It can affect and harm the developing baby. Consult your doctor before taking Stamlo Trio 80/6.25 Tablet if you plan to become pregnant or already pregnant. Your doctor will weigh the potential risks and benefits before prescribing Stamlo Trio 80/6.25 Tablet .

Country of origin

India

Manufacturer/Marketer address

Dr. Reddy'S Laboratories Ltd., 8-2-337, Road No. 3, Banjara Hills, Hyderabad, Telangana 500034, India
Other Info - STA0805

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 6:45 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.drugs.com/amlodipine.html
  2. https://www.drugs.com/mtm/telmisartan.html
  3. https://www.drugs.com/mtm/chlorthalidone.html
  4. https://pubchem.ncbi.nlm.nih.gov/compound/Amlodipine
  5. https://www.webmd.com/drugs/2/drug-153181/telmisartan-amlodipine-oral/details
  6. https://www.webmd.com/drugs/2/drug-3951/chlorthalidone-oral/details

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