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compositionComposition:TOFACITINIB-2%W/W
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Tofaplus Ointment 15 gm is used to treat alopecia areata (hair loss). It is also used in the treatment of atopic dermatitis (eczema). It contains Tofacitinib, which helps prevent hair cell death and promotes new hair growth, and also reduces the redness and itchiness associated with skin infections. This medicine may occasionally cause side effects, including excessive hair growth, headaches, skin irritation, itching, and rashes. Avoid using Tofaplus Ointment 15 gm if you are allergic to it or any other ingredients present in it.

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Written By Dr. Lakshmithulasi Yarragunta , PharmD (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

TOFACITINIB-2%W/W

Manufacturer/Marketer :

Bioswizz Pharmaceuticals Ltd

Consume Type :

Topical

Expires on or after :

Jan-28

Return Policy :

Not Returnable

About Tofaplus Ointment 15 gm

Tofaplus Ointment 15 gm is a topical prescription medicine that belongs to a group of medicines called Janus kinase (JAK) inhibitors. It may be prescribed by dermatologists to help manage certain inflammatory skin conditions by reducing overactive immune activity in the skin. This medicine may be used for conditions such as atopic dermatitis (eczema), vitiligo, or alopecia areata.

For the best results, apply Tofaplus Ointment 15 gm exactly as prescribed, usually once or twice daily depending on your treatment plan. Applying it at the same time each day helps maintain consistent treatment. Along with treatment, keeping your skin well moisturised, avoiding known triggers, and wearing loose, breathable clothing may help improve treatment outcomes.

Most people tolerate Tofaplus Ointment 15 gm well. Mild burning, stinging, redness, or itching at the application site may occur during the first few days of treatment and often improve as your skin adjusts. Contact your doctor if these symptoms become severe, persist, or if you notice signs of infection such as increasing pain, pus, swelling, or warmth around the treated area.

Do not use Tofaplus Ointment 15 gm if you are allergic to any of its ingredients or if you have an untreated bacterial, viral, or fungal skin infection where the medicine is to be applied. Tell your doctor before starting treatment if you have a history of frequent infections, cancer, heart disease, stroke, blood clots, or a weakened immune system.

Some medicines and skincare products may affect how topical Tofaplus Ointment 15 gm works. Inform your doctor about all prescription medicines, over-the-counter products, herbal supplements, and topical creams you are using. If you are pregnant, planning pregnancy, breastfeeding, or treating a child, discuss the potential benefits and risks before starting treatment.

Uses of Tofaplus Ointment 15 gm

Tofaplus Ointment 15 gm is used to treat certain skin conditions. The detailed uses of Tofaplus Ointment 15 gm are as follows:

  • Atopic Dermatitis (Eczema): It may be prescribed to help reduce itching, redness, inflammation, and dry, scaly skin.
  • Vitiligo: It may be used to help reduce immune-related damage to pigment-producing cells.
  • Alopecia Areata: It may help promote hair regrowth in selected patients under a dermatologist's supervision.

Key Benefits

Tofaplus Ointment 15 gm provides targeted treatment directly to affected skin, helping control inflammation while limiting exposure to the rest of the body. When used as prescribed, it may offer the following benefits:

  • Works directly where it is applied, helping reduce inflammation with lower systemic exposure than oral JAK inhibitors.
  • Helps reduce persistent itching, burning, and discomfort associated with inflammatory skin conditions.
  • Helps calm the overactive immune response responsible for redness and swelling.
  • Allows damaged skin to heal more effectively by reducing ongoing inflammation.
  • Offers an alternative for patients who require a steroid-sparing treatment under medical supervision.
  • With continued treatment, it may help improve skin texture, reduce inflammation, and encourage repigmentation or hair regrowth in appropriate conditions.

Directions for Use

  • It is recommended to apply twice daily or as advised by the doctor.
  • Apply the recommended amount of Tofaplus Ointment 15 gm to the affected scalp areas with clean, dry hands, and gently massage it into the skin with your fingers.
  • Wash your hands before and after applying it.
  • It is only for external use.

How Tofaplus Ointment 15 gm Works

Tofaplus Ointment 15 gm belongs to a group of medicines called Janus kinase (JAK) inhibitors. JAK proteins are natural signalling proteins inside your body's cells that help transmit messages involved in inflammation and immune responses. In certain skin conditions, these signals become overactive and contribute to itching, redness, inflammation, pigment loss, or immune-related hair loss. When applied to the skin, Tofaplus Ointment 15 gm blocks selected JAK signalling pathways, helping reduce the excessive immune response only in the treated area. This allows inflammation to settle, relieves itching, and supports healthier skin repair.
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Alcohol

Consult your doctor

No interaction was found. Please consult your doctor before using Tofaplus Ointment 15 gm.

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Pregnancy

Consult your doctor

Please consult your doctor before starting Tofaplus Ointment 15 gm if you are pregnant or planning pregnancy.

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Breast Feeding

Consult your doctor

It is not known if Tofaplus Ointment 15 gm passes into the breast milk and harms a baby during breastfeeding. If you are a nursing mother, please consult the doctor before using Tofaplus Ointment 15 gm.

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Driving

Consult your doctor

It is unknown whether Tofaplus Ointment 15 gm affects your ability to drive or not. Please consult your doctor.

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Liver

Consult your doctor

Inform your doctor if you have liver disease before using Tofaplus Ointment 15 gm. In case of atopic dermatitis, this medicine is contraindicated for use in severe hepatic disease.

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Kidney

Consult your doctor

If you have kidney problems, inform your doctor before using Tofaplus Ointment 15 gm.

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Children

Unsafe

Tofaplus Ointment 15 gm is not recommended for use in children below 18 years of age as the safety and efficacy are not established.

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Heart

Consult your doctor

Please consult your doctor if you have any heart problems before taking Tofaplus Ointment 15 gm.

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Geriatrics

Consult your doctor

Please consult a doctor if you have any concerns regarding the use of Tofaplus Ointment 15 gm in elderly patients.

What if I have taken an overdose of Tofaplus Ointment 15 gm

Applying more Tofaplus Ointment 15 gm than prescribed is unlikely to cause serious problems but may increase skin irritation or redness. If you accidentally apply a large amount, gently wipe away any excess medicine and continue using it as directed. If the medicine is accidentally swallowed, or if you develop severe skin irritation, allergic symptoms, or any unusual symptoms after excessive use, seek immediate medical attention or contact your nearest poison control centre.

Diet & Lifestyle Advise

  • Keep Your Skin Moisturised: Apply a fragrance-free moisturiser regularly to help strengthen your skin barrier. Ask your doctor how long to wait between applying Tofaplus Ointment 15 gm and your moisturiser.
  • Avoid Skin Triggers: Identify and avoid factors that worsen your skin condition, such as harsh soaps, fragrances, allergens, excessive sweating, or irritants.
  • Wear Soft, Breathable Clothing: Loose cotton clothing helps reduce friction and irritation on affected skin.
  • Protect Your Skin from the Sun: If you have vitiligo or sun-sensitive skin, wear protective clothing and use sunscreen on exposed skin as recommended by your doctor.
  • Manage Stress: Stress can worsen inflammatory skin conditions. Relaxation techniques, regular exercise, adequate sleep, and mindfulness practices may help reduce flare-ups.
  • Avoid Scratching: Keeping your nails short and avoiding scratching can reduce skin damage and lower the risk of infection.
  • Follow Your Treatment Plan: Attend follow-up appointments so your doctor can monitor your progress and adjust treatment if needed.
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How Soon It Starts Working

  • The time required for Tofaplus Ointment 15 gm to start to work: The time required for Tofaplus Ointment 15 gm to show its action is unknown.
  • The time for which the effects of Tofaplus Ointment 15 gm last: The duration of action for Tofaplus Ointment 15 gm is unknown.

What if you forget to take Tofaplus Ointment 15 gm

If you miss an application, apply it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed application and continue with your regular schedule. Do not apply extra medicine or double the amount to make up for a missed dose.

Storage

• Store Tofaplus Ointment 15 gm according to the instructions provided on the product label or package insert.

Drug Warnings

  • Use only as prescribed: Apply Tofaplus Ointment 15 gm only to the affected skin areas and for the duration recommended by your doctor.
  • Discuss your medical history: Tell your doctor if you have a history of frequent infections, cancer, heart disease, stroke, blood clots, or a weakened immune system before starting treatment.
  • Check the product before use: Do not use the cream or ointment if the seal is broken, the product has changed colour, separated, or has an unusual smell.
  • Avoid sensitive areas: Unless specifically directed by your doctor, do not apply Tofaplus Ointment 15 gm to your eyes, inside your nose or mouth, or on open wounds.
  • Do not cover treated skin: Avoid airtight bandages or occlusive dressings unless advised by your healthcare provider, as they can increase medicine absorption.
  • Wash your hands after application: This helps prevent accidentally transferring the medicine to healthy skin or to the moist inner surfaces of your body, such as the inside of your nose or mouth.
  • Avoid sharing your medicine: Tofaplus Ointment 15 gm has been prescribed specifically for your condition and should not be shared with others.
  • Monitor your skin regularly: Contact your doctor if your condition worsens, new symptoms develop, or you notice signs of infection, such as increasing redness, swelling, warmth, pus, or pain.
  • Pregnancy and breastfeeding: Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding. Avoid applying the medicine to the breast or nipple area while breastfeeding unless your doctor advises otherwise.

Drug-Drug Interactions

verifiedApollotooltip
  • Other Topical Medicines: Applying steroid creams, medicated ointments, or other topical products to the same area may affect how Tofaplus Ointment 15 gm is absorbed or increase skin irritation. Follow your doctor's instructions regarding the timing of each product.
  • Immunosuppressive Medicines: Using oral immunosuppressants or other medicines that weaken the immune system alongside Tofaplus Ointment 15 gm may increase the risk of infections and requires medical supervision.
  • Phototherapy: If you are receiving ultraviolet (UV) phototherapy for vitiligo or another skin condition, tell your doctor before starting Tofaplus Ointment 15 gm. Your treatment schedule may need adjustment to maximise benefits and minimise irritation.
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

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  • No clinically significant food interactions have been established.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[MISCELLANEOUS]

FAQs

Tofaplus Ointment 15 gm is used to treat alopecia areata (hair loss) and atopic dermatitis.
Tofaplus Ointment 15 gm contains Tofacitinib, a Janus kinase (JAK) inhibitor, which affects hematopoiesis and immune cell activity by transmitting signals resulting from cytokine or growth factor-receptor interactions on the cellular membrane.
The duration of the medicine will depend on the indication/ use for which it is prescribed. However, it is advised to complete the treatment course your doctor prescribes for better recovery.
Tofaplus Ointment 15 gm may cause certain side effects such as excessive hair growth, headache, skin irritation, itching, rashes, nausea, vomiting, and fatigue. If you experience any other symptoms that may be due to Tofaplus Ointment 15 gm, please consult your doctor or pharmacist for further advice.
Yes, but only if your doctor has specifically advised you to treat that area. Avoid getting the medicine into your eyes, eyelids, nose, or mouth. If accidental contact occurs, rinse thoroughly with clean water.
Improvement depends on the condition being treated. Itching and inflammation may improve within a few weeks, while vitiligo or alopecia areata often require several months of regular treatment. Arrange a follow-up appointment if your symptoms do not improve as expected.
No. Tofaplus Ointment 15 gm is a Janus kinase (JAK) inhibitor, a non-steroidal medicine that works by reducing overactive immune signals involved in inflammation.
No. Continue using it for the full duration prescribed unless your doctor advises otherwise. Stopping treatment too early may allow your symptoms to return.
Avoid covering the treated area with airtight bandages or dressings unless your doctor specifically instructs you to do so, as this can increase medicine absorption.
Rinse your eyes immediately with plenty of clean water for several minutes. Seek medical advice if irritation, pain, blurred vision, or redness continues.
Yes, but allow the medicine to absorb first. Ask your healthcare provider how long you should wait before applying moisturisers, cosmetics, or sunscreen to the same area.
Tell your doctor if you are pregnant, planning pregnancy, or breastfeeding before starting treatment. If you are breastfeeding, avoid applying the medicine to the breast or nipple area to prevent accidental exposure to your baby.
Some inflammatory skin conditions may relapse after treatment is stopped. Do not restart Tofaplus Ointment 15 gm on your own. Schedule a review with your dermatologist to determine whether further treatment or an alternative approach is needed.
Its safety and effectiveness in children depend on the age and condition being treated. A paediatrician or dermatologist will decide whether it is suitable for your child.
Seek emergency medical care immediately or call 112 if you develop swelling of your face, lips, tongue, or throat, difficulty breathing, or any signs of a severe allergic reaction after applying Tofaplus Ointment 15 gm. These reactions are rare but require urgent treatment.

Disclaimer

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Country of origin

India

Manufacturer/Marketer address

New No 241 Old No 92/15, Sathangadu Colony Street, Tiruvottiyur, Chennai - 600019
Other Info - TOF0157
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