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Crocin Pain Relief Tablet 15's
Crocin Pain Relief Tablet 15's
Crocin Pain Relief Tablet 15's
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More about the Product

Composition :

CAFFEINE-50MG+PARACETAMOL-650MG

Manufacturer/Marketer :

GlaxoSmithKline Pharmaceuticals Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Crocin Pain Relief Tablet

Crocin Pain Relief Tablet is used to treat mild to moderate pain, including headache, backache, migraine, rheumatic and muscle pain, toothache and period pain. Pain is caused by the activation of pain receptors due to the release of certain chemicals or enzymes.

Crocin Pain Relief Tablet contains paracetamol and caffeine. Paracetamol inhibits the release of these enzymes and alleviates pain. Caffeine increases the efficacy of paracetamol by improving its absorption, thereby prolonging analgesic action.

The common side effects of Crocin Pain Relief Tablet include agitation, nervousness, and insomnia. Everyone does not need to experience the above side effects, as they vary for each person depending on their health, underlying conditions, age, weight, and gender. In case of any discomfort, speak with a doctor.

Do not take Crocin Pain Relief Tablet if you're allergic to any ingredient in it. Crocin Pain Relief Tablet is not recommended for use during pregnancy or breastfeeding. Ask your healthcare professional for advice if you have any concerns. Do not use Crocin Pain Relief Tablet in more than the prescribed doses or for a longer duration, as it may cause adverse effects.

Description

Crocin Pain Relief Tablet helps in the treatment of headache

Key Ingredients

Paracetamol, Caffeine.

Uses of Crocin Pain Relief Tablet

Crocin Pain Relief Tablet is used in the treatment of Pain relief. The detailed uses of Crocin Pain Relief Tablet are as follows:

  • Mild to Moderate Pain Relief: Crocin Pain Relief Tablet relieves headache, backache, migraine, rheumatic and muscle pain, toothache, and period pain, providing effective pain management for various conditions.
  • Fever Reduction: Crocin Pain Relief Tablet helps reduce high temperature associated with various conditions accompanied by pain.

Health Queries

I am experiencing pain in my eyes, head, and back, and my exams start in two days. What should I do to manage the pain?

Chandrakanta Jena

Chandrakanta Jena

Pharm D

Your symptoms are likely due to eye strain and tension, possibly caused by poor posture and prolonged reading or screen use. Try to rest your eyes regularly, use proper lighting, stay well hydrated, and take short breaks to stretch your back and relax your mind. You may take a mild pain reliever like paracetamol if needed, but avoid overuse. If the pain is severe, persistent, or accompanied by vision problems or fever, please consult a doctor promptly.

I have a headache. Can you suggest a solution?

Y. Lakshmi Thulasi

Y. Lakshmi Thulasi

Pharm-D (Post baccalaureate)

Rest in a dark, quiet space and drink plenty of water if you have a slight headache. If the headache is severe, persistent, or accompanied by other symptoms, consult a physician instead of taking paracetamol.

I've had regular headaches lasting 1 to 2 days. Can I take crocin pain relief?

Y. Lakshmi Thulasi

Y. Lakshmi Thulasi

Pharm-D (Post baccalaureate)

Yes, you can use Crocin (paracetamol) to temporarily relieve headaches. See a doctor to determine the underlying cause if your headaches are severe, frequent, or getting worse.

I have a little headache and a blocked nose, but no fever.

Y. Lakshmi Thulasi

Y. Lakshmi Thulasi

Pharm-D (Post baccalaureate)

A common cold or sinus congestion is typically the cause of a minor headache accompanied by a clogged nose and no fever. To reduce symptoms, take a nap, drink plenty of water, and utilize saline nasal sprays or moderate analgesics like paracetamol.

I have fever, body pains, and a headache. Will crocin help?

Y. Lakshmi Thulasi

Y. Lakshmi Thulasi

Pharm-D (Post baccalaureate)

Indeed, Crocin (paracetamol) can help lower your headache, body aches, and fever. See a doctor for a thorough evaluation if symptoms intensify or last longer than a few days.

Have a query?

Side effects of Crocin Pain Relief Tablet
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
  • Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.
  • Identify the medicine causing acidosis and talk to your doctor whether it can be discontinued or substituted with other medicine.
  • If you experience symptoms of acidosis like rapid breathing, confusion, overtiredness or nausea, contact your doctor immediately.
  • Your doctor may recommend dietary changes like changes in potassium intake based on the type of acidosis.
  • Consume more fruits, vegetables, and cruciferous foods like cabbage, kale, and broccoli.
  • Reduced alcohol intake can enhance liver enzyme function.
  • Oxidative stress can be managed by eating foods rich in antioxidants, such as vitamins C and E.
  • Liver function tests regularly can help manage increased levels of AST.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
  • Include iron-rich foods like dark leafy vegetables, lean red meat, legumes and fish in your diet.
  • Consume vitamin C-rich foods as they aid iron absorption.
  • Limit tea, cocoa, and coffee as these can slow iron absorption.
  • Exercise regularly; however, do not overdo it.
Here are the seven steps to manage medication-triggered Dyspnea (Difficulty Breathing or Shortness of Breath):
  • Tell your doctor immediately if you experience shortness of breath after taking medication.
  • Your doctor may adjust the medication regimen or dosage or give alternative medical procedures to minimize the symptoms of shortness of breath.
  • Monitor your oxygen levels and breathing rate regularly to track changes and potential side effects.
  • For controlling stress and anxiety, try relaxation techniques like deep breathing exercises, meditation, or yoga.
  • Make lifestyle changes, such as quitting smoking, exercising regularly, and maintaining a healthy weight.
  • Seek emergency medical attention if you experience severe shortness of breath, chest pain, or difficulty speaking.
  • Follow up regularly with your doctor to monitor progress, adjust treatment plans, and address any concerns or questions.

Directions for Use

  • Take Crocin Pain Relief Tablet with or without food as advised by your doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Swallow Crocin Pain Relief Tablet as a whole with a glass of water.
  • Do not crush, break, or chew it.

Key Benefits

  • Crocin Pain Relief Tablet is a combination medication containing paracetamol (acetaminophen) and caffeine.
  • Crocin Pain Relief Tablet effectively treats mild to moderate pain, including headache, backache, migraine, rheumatic and muscle pain, toothache and period pain.
  • On the other hand, it also relieves discomfort associated with colds, influenza, and sore throats, and helps reduce fever.
  • Paracetamol inhibits the release of these enzymes and alleviates pain. It also has an antipyretic effect, reducing body temperature in cases of fever.
  • Caffeine increases the efficacy of paracetamol by improving its absorption, thereby prolonging analgesic action.

How Crocin Pain Relief Tablet Works

Crocin Pain Relief Tablet contains paracetamol (acetaminophen) and caffeine. Paracetamol inhibits the release of these enzymes and alleviates pain. Caffeine increases the efficacy of paracetamol by improving its absorption, thereby prolonging analgesic action. Paracetamol also has an antipyretic effect and can reduce body temperature in cases of fever.

Storage

Store in a cool and dry place away from sunlight

What if I have taken an overdose of Crocin Pain Relief Tablet

Do not take more than the prescribed dose of Crocin Pain Relief Tablet as it may cause overdose and increase the risk of irreversible liver damage. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

  • Consult your doctor immediately if you have any allergic reactions such as skin rash, swelling of the face/lips/tongue/throat, wheezing, or shortness of breath.
  • Do not take it if you have any known allergy to paracetamol (acetaminophen) or caffeine.
  • People with kidney, liver, alcohol dependence, heart disease, or persistent headaches should avoid taking Crocin Pain Relief Tablet unless instructed by the doctor.
  • Inform your doctor if you are taking any other prescribed or over-the-counter medications before taking this medicine.
  • Do not increase your dose or duration of the medicine without consulting the doctor.

Drug-Drug Interactions

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CaffeineTranylcypromine
Critical
CaffeineIsocarboxazid
Critical

Drug-Drug Interactions

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CaffeineTranylcypromine
Critical
How does the drug interact with Crocin Pain Relief Tablet:
Coadministration of tranylcypromine with Crocin Pain Relief Tablet can in cause severe high blood pressure.

How to manage the interaction:
Taking Crocin Pain Relief Tablet with Tranylcypromine is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience headache, confusion, blurred vision, problems with speech or balance, nausea, vomiting, chest pain, convulsions, and sudden numbness or weakness (especially on one side of the body). Do not discontinue any medications without consulting a doctor.
CaffeineIsocarboxazid
Critical
How does the drug interact with Crocin Pain Relief Tablet:
Taking these two together can cause your blood pressure to rise, a condition known as a hypertensive crisis.

How to manage the interaction:
Taking Crocin Pain Relief Tablet with Isocarboxazid is not recommended, please consult your doctor before taking it. It can be taken if your doctor prescribes it. Do not stop taking any medication without consulting your doctor.
CaffeineLinezolid
Critical
How does the drug interact with Crocin Pain Relief Tablet:
Taking these two together can cause your blood pressure to rise, a condition known as a hypertensive crisis.

How to manage the interaction:
Taking Crocin Pain Relief Tablet with Linezolid is not recommended, please consult your doctor before taking it. It can be taken if your doctor prescribes it. Do not stop taking any medication without consulting your doctor.
CaffeinePhenelzine
Critical
How does the drug interact with Crocin Pain Relief Tablet:
Taking these two together can cause your blood pressure to rise, a condition known as a hypertensive crisis.

How to manage the interaction:
Taking Crocin Pain Relief Tablet with Phenelzine is not recommended, please consult your doctor before taking it. They can be taken if your doctor advises it. Do not stop taking any medication without consulting your doctor.
ParacetamolLomitapide
Severe
How does the drug interact with Crocin Pain Relief Tablet:
Co-administration of Lomitapide and Crocin Pain Relief Tablet may increase the risk of severity of liver injury.

How to manage the interaction:
Although there is a possible interaction between Crocin Pain Relief Tablet and Lomitapide, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
ParacetamolMipomersen
Severe
How does the drug interact with Crocin Pain Relief Tablet:
Co-administration of Mipomersen with Crocin Pain Relief Tablet may increase the risk or severity of liver injury.

How to manage the interaction:
There may be a possibility of interaction between Crocin Pain Relief Tablet and Mipomersen, but it can be taken if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
ParacetamolValdecoxib
Severe
How does the drug interact with Crocin Pain Relief Tablet:
Co-administration of Crocin Pain Relief Tablet and Valdecoxib may increase the risk or severity of adverse effects.

How to manage the interaction:
Although there is a possible interaction between Crocin Pain Relief Tablet and Valdecoxib, you can take these medicines together if prescribed by a doctor. However, if the side effects worsen, please consult a doctor.
ParacetamolKetoconazole
Severe
How does the drug interact with Crocin Pain Relief Tablet:
Co-administration of Crocin Pain Relief Tablet and Ketoconazole may increase the risk of liver injury.

How to manage the interaction:
Although there is a possible interaction between Crocin Pain Relief Tablet and Ketoconazole, you can take these medicines together if prescribed by a doctor. However, if you have joint pain or swelling, fever, chills, unusual bleeding or bruising, skin rash, itching, over-tiredness, nausea, vomiting, loss of appetite, stomach pain, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes, contact a doctor immediately as these may be signs and symptoms of liver damage. Do not discontinue the medication without consulting a doctor.
ParacetamolKetamine
Severe
How does the drug interact with Crocin Pain Relief Tablet:
Co-administration of ketamine and Crocin Pain Relief Tablet may decrease the effectiveness of Ketamine which could result in a higher blood level.

How to manage the interaction:
Although taking Ketamine and Crocin Pain Relief Tablet together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you're feeling very sleepy or having trouble breathing, it's important to contact your doctor right away. Do not stop using any medications without a doctor's advice.
ParacetamolTeriflunomide
Severe
How does the drug interact with Crocin Pain Relief Tablet:
Co-administration of Teriflunomide with Crocin Pain Relief Tablet may increase the risk or severity of Liver problems.

How to manage the interaction:
Taking Crocin Pain Relief Tablet with Teriflunomide together can possibly result in an interaction, but it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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CAFFEINE-50MG+PARACETAMOL-650MGFruit juices
Mild

Drug-Food Interactions

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CAFFEINE-50MG+PARACETAMOL-650MGFruit juices
Mild
Common Foods to Avoid:
Grapefruit Juice

How to manage the interaction:
Consumption of grape juice increases the effect of caffeine. Avoid taking grape juice with caffeine, as it causes an interaction. If you experience any symptoms, consult the doctor immediately.

Diet & Lifestyle Advise

  • Get adequate sleep as resting the muscles can help in reducing inflammation and swelling.
  • Acupuncture, massage and physical therapy may also be helpful.
  • Eat foods rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
  • Foods containing flavonoids such as soy, berries, broccoli, grapes and green tea help in reducing inflammation.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Practice relaxation techniques that help to calm down the mind and reduce pain levels.
  • Avoid smoking and alcohol consumption.

Habit Forming

No

Therapeutic Class

[ANALGESIC AND ANTIPYRETIC AGENT]
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Alcohol

Unsafe

Crocin Pain Relief Tablet is unsafe with alcohol as it may cause gastrointestinal side effects such as abdominal pain and vomiting.

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Pregnancy

Consult your doctor

Paracetamol presnet in Crocin Pain Relief Tablet is a Category B pregnancy medicine, but caffeine use is limited during pregnancy. So, it should be used during pregnancy only if the doctor has prescribed it.

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Breast Feeding

Consult your doctor

Crocin Pain Relief Tablet should not be used in nursing mothers unless clearly necessary. So, inform your doctor if you are a nursing mother.

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Driving

Safe if prescribed

Crocin Pain Relief Tablet may not affect your ability to drive or operate machinery.

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Liver

Caution

Crocin Pain Relief Tablet is to be taken with caution, especially if you have a history of liver diseases such as alcoholic liver disease. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Crocin Pain Relief Tablet is to be taken with caution, especially if you have a history of kidney diseases. You may require dose adjustments based on your health condition.

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Children

Consult your doctor

The dose of Crocin Pain Relief Tablet needs to be adjusted, and its use should be recommended by a child specialist only.

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Heart

Unsafe

Crocin Pain Relief Tablet should be avoided in cardiac patients as it can lead to serious cardiavascular risks

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Geriatrics

Caution

Crocin Pain Relief Tablet should be used under caution in geriatric patients as it can lead to serious side effects/

FAQs

Crocin Pain Relief Tablets are an over-the-counter medicine used primarily to treat mild to moderate pain. The powerful combination of paracetamol and caffeine provides rapid relief from headaches, migraines, toothaches, menstrual cramps, body aches, and musculoskeletal pain, while also acting as a fever reducer.

Yes, it is highly effective for headaches. The addition of 50mg of caffeine enhances the pain-relieving effects of paracetamol. Caffeine helps constrict dilated blood vessels in the brain, which is particularly beneficial for alleviating tension headaches and migraines quickly.

Crocin Advance contains only paracetamol (with an Optizorb technology for faster dissolution), making it a standard fever and pain medication. Crocin Pain Relief contains paracetamol plus caffeine, making it a stronger, targeted formulation specifically designed for more severe pain like stubborn headaches and acute body aches.

Yes. Paracetamol is a well-known antipyretic. It works directly on the brain’s temperature control centre to safely and effectively lower elevated body temperatures during bacterial or viral infections.

Adults and children over 12 years can take 1 tablet every 4 to 6 hours as needed for pain or fever. However, you must never exceed 4 tablets in a standard 24-hour period to prevent the risk of liver toxicity.

When taken at the recommended dosage, side effects are rare. However, sensitive individuals might experience mild nausea, stomach upset, or jitteriness (due to the caffeine). Stop use and see a doctor immediately if you experience allergic reactions like skin rashes or swelling.

Yes, you can buy Crocin Pain Relief online securely. It is classified as an OTC (over-the-counter) medication, meaning it does not legally require a doctor's prescription for purchase. However, it should always be used responsibly according to the label directions.

While standard paracetamol is generally considered safe during pregnancy, this specific variant contains caffeine. High caffeine intake is generally discouraged during pregnancy. Always consult your obstetrician or doctor before taking this product if you are pregnant or breastfeeding.

No. You must avoid consuming alcohol while taking any medication containing paracetamol. The liver metabolises both alcohol and paracetamol, and combining the two puts excessive strain on the organ, significantly increasing the risk of severe liver damage.

Caffeine acts as an "analgesic adjuvant". Clinical studies show that adding a small amount of caffeine to paracetamol can boost its pain-relieving efficacy by up to 40%, ensuring that the medicine works faster and stronger than standard paracetamol alone.

Crocin Pain Relief Tablet belongs to the class of analgesic medication. It is primarily used to treat mild to moderate pain, including headache, backache, migraine, rheumatic and muscle pain, toothache and period pain.

Crocin Pain Relief Tablet contains paracetamol (acetaminophen) and caffeine. Paracetamol inhibits the release of these enzymes and alleviates pain. Caffeine increases the efficacy of paracetamol by improving its absorption, thereby prolonging analgesic action. Paracetamol also has an antipyretic effect and can reduce body temperature in cases of fever.

The dose of Crocin Pain Relief Tablet depends on your condition and severity. Consult a doctor to know the exact dose and duration.

Take the missed dose as soon as you remember, if the next dose is not due within a few hours. Do not double the next dose. Take your next doses at the fixed time.

If there is an overdose, you may experience signs of liver damage such as nausea, vomiting, loss of appetite, rash, or dark urine. Consult a doctor immediately if you have any discomfort.

Crocin Pain Relief Tablet is recommended to use not more than 2 to 3 days per week. Prolonged use may lead to medicine-overuse (rebound) headaches.

Country of origin

India

Manufacturer/Marketer address

24-25 Floor, One Horizon Center Golf Course Road, DLF Phase 5 Gurgaon 122002, India
Other Info - CRO0007

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Nov 21, 2025 | 11:23 AM IST

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