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About S ETODOLAC

S ETODOLAC belongs to the non-steroidal anti-inflammatory drug (NSAID) class. It is used to relieve mild to moderate pain and inflammation in patients with osteoarthritis and rheumatoid arthritis. Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body. Arthritis, also known as joint inflammation, is the tenderness and swelling of the joints. Symptoms include swelling, pain, and stiffness. 

S ETODOLAC contains S Etodolac as an active ingredient. It works by blocking the effect of chemical messengers called prostaglandins by inhibiting cyclooxygenase (COX) enzymes. Thus, it reduces mild to moderate pain and inflammation at the injured or damaged site.

S ETODOLAC should be taken as prescribed by your doctor. Your doctor will decide the dose of the medicine based on the severity of the condition. S ETODOLAC may cause common side effects such as abdominal pain, diarrhoea, indigestion, dizziness, headache, rashes, flushes, palpitations, confusion, nervousness, blurred vision, dry mouth, increased blood sugar levels, loss of appetite, nausea and vomiting. Most of these side effects do not require medical attention and will resolve gradually. However, you are advised to talk to your doctor if you experience these side effects persistently.

S ETODOLAC should be avoided if you are allergic to it. To rule out any interactions, inform your doctor about your health condition and the medicines you take. This medicine should be used cautiously in patients with gastrointestinal disorders, diabetes, cardiovascular disorders, serious anaphylactic reactions, and liver/kidney disease. S ETODOLAC should not be used in patients with asthma, urticaria, or bleeding disorders as it can worsen the conditions. S ETODOLAC may cause drowsiness and dizziness, so drive with caution. S ETODOLAC is not recommended for children below 16 years of age as safety and efficacy have not been established. Avoid consuming alcohol with S ETODOLAC as it could cause increased drowsiness and dizziness; it might also increase the risk of stomach bleeding. It is advised not to take more than the prescribed dose of medicine and for a longer period. If you are pregnant, planning for a pregnancy or are breastfeeding, inform your doctor before taking S ETODOLAC.

Uses of S ETODOLAC

Pain relief (Osteoarthritis, Rheumatoid Arthritis)

Medicinal Benefits

S ETODOLAC contains S Etodolac as an active ingredient, which belongs to the non-steroidal anti-inflammatory drug (NSAID) class. It works by blocking the effect of chemical messengers called prostaglandins by inhibiting cyclooxygenase (COX) enzymes. Thus, it reduces mild to moderate pain and inflammation at the injured or damaged site. S ETODOLAC is used as a painkiller for short-term pain management.

Directions for Use

Take S ETODOLAC as prescribed by your doctor. Take it with food to prevent stomach aches. Swallow the medicine as a whole with a glass of water. Do not chew, crush or break the medicine.

Storage

Store in a cool and dry place away from sunlight

Side Effects of S ETODOLAC

  • Nausea
  • Abdominal pain
  • Indigestion
  • Diarrhoea
  • Constipation
  • Fatigue
  • Flushes
  • Dizziness
  • Increased blood sugar levels
  • Rashes
  • Palpitations
  • Blurred vision
  • Dry mouth
  • Loss of appetite

In-Depth Precautions and Warning

Drug Warnings

If you are allergic to S ETODOLAC, you should avoid it. Keep your doctor informed about your medical condition and medications to rule out any interactions. In patients with gastrointestinal disorders, diabetes, cardiovascular disorders, severe anaphylactic reactions, or liver/kidney disease, this medication should be used with caution. S ETODOLAC should not be used in patients with a history of liver disease, kidney disease, peptic ulcer disease, bleeding disorders, heart failure, asthma, or IBD because it can worsen the conditions. S ETODOLAC can make you drowsy and dizzy, so drive carefully. Consuming alcohol with S ETODOLAC may cause increased drowsiness and dizziness and an increased risk of stomach bleeding. Taking more medicine than prescribed or for a longer period is not recommended. Inform your doctor if you are pregnant, planning a pregnancy, or breastfeeding before taking S ETODOLAC.

Drug Interactions

Drug-Drug Interactions: S ETODOLAC may interact with antihypertensive medicines (captopril, Lisinopril, losartan), diuretics (furosemide), mood stabiliser (lithium), DMARD (methotrexate), steroids (prednisolone), aspirin and blood-thinners (clopidogrel, warfarin, enoxaparin), anti-gout drug (probenecid), anti-epileptic drugs (phenytoin, carbamazepine), psychoactive drugs (fluoxetine, alprazolam), and anti-depressants (SSRI’s like citalopram, escitalopram) etc.

Drug-Food Interactions: Avoid alcohol consumption and smoking.

Drug-Disease Interactions: S ETODOLAC should be used with caution in patients with a known hypersensitivity disorder, diabetes mellitus, epilepsy, kidney disease, liver disease, cardiovascular disorders, asthma, bleeding disorders, peptic ulcers, hypertension, anaemia, and any disease-causing swelling in the feet and hands.

Drug-Drug Interactions Checker List:

  • PREDNISOLONE
  • ASPIRIN
  • CLOPIDOGREL
  • WARFARIN
  • PHENYTOIN
  • CARBAMAZEPINE
  • FLUOXETINE
  • ESCITALOPRAM
  • PROBENECID
  • CAPTOPRIL
  • METHOTREXATE
  • Safety Advice

    • Safety Warning

      Alcohol

      unsafe

      You are advised not to consume alcohol with S ETODOLAC as it can increase dizziness.

    • Safety Warning

      Pregnancy

      caution

      If you are pregnant or planning pregnancy, inform your doctor before receiving S ETODOLAC. Your doctor may prescribe this medicine if the benefits outweigh the risks.

    • Safety Warning

      Breast Feeding

      unsafe

      S ETODOLAC passes into breast milk. Hence, avoid breastfeeding while taking S ETODOLAC. Please consult your doctor if you have any concerns.

    • Safety Warning

      Driving

      unsafe

      S ETODOLAC may cause dizziness and drowsiness, affecting your driving ability. Hence, drive or operate machinery only when you are alert.

    • Safety Warning

      Liver

      caution

      If you have a pre-existing or history of liver disease, inform your doctor before taking S ETODOLAC. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

    • Safety Warning

      Kidney

      caution

      If you have a pre-existing or history of kidney disease, inform your doctor before taking S ETODOLAC. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

    • Safety Warning

      Children

      unsafe

      S ETODOLAC is not recommended for use in children below 16 years of age as the safety and efficacy are not established.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Stay hydrated by drinking plenty of water.
    • Make a balanced diet. Eat more fruits, green leafy vegetables, nuts, oily fish etc.
    • Avoid or decrease the intake of sweets and sugars, as these can worsen inflammation.
    • Avoid alcohol consumption, as this can increase the risk of bleeding.
    • Try to do meditation and deep breathing to reduce overall stress and pain.
    • Stop smoking, as it is known to worsen pain conditions.
    • Engage in mild physical exercise daily and keep your body active.
    • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
    • Get adequate sleep, as resting the muscles can help reduce inflammation and swelling.
    • Follow heat or cold therapy, and apply a cold or hot compress on the joints for 15-20 minutes regularly.

    Special Advise

    • Do not discontinue taking S ETODOLAC abruptly or without the physician's advice.
    • It is advised not to take more than the prescribed dose or take this medicine for a longer duration.
    • Your doctor may suggest blood tests to check for any cause of anaemia (low blood levels).
    • Before starting the treatment, it is important to inform the doctor if you have conditions like peptic ulcers or any bleeding disorders.

    Patients Concern

    Disease/Condition Glossary

    Pain: Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body. Pain may be dull or sharp, it might be constant or may come and go. The tolerance level of pain might vary from person to person. Pain can be generalized (overall body aches) or localized (affecting a specific area of the body). Pain can be considered a good thing as it helps us know that something is wrong in the body and thereby helps diagnose the condition. The common causes of pain include headache, muscle strain, cramps, cuts, bone fractures, and arthritis.

    Osteoarthritis: Osteoarthritis is a joint disease in which the two ends of the joints come together due to the breakdown of a protective covering called cartilage. Due to the absence of this protective covering, the joints rub against each other, leading to pain and stiffness. Symptoms include pain, stiffness, inflammation and tenderness.

    Rheumatoid arthritis: Rheumatoid arthritis is an auto-immune disease (the body's immune system attacks its tissue), leading to joint pain and damage. Symptoms of rheumatoid arthritis include pain, swelling, stiffness, deformities and loss of joint function.

    FAQs

    How does S ETODOLAC work?

    S ETODOLAC contains S Etodolac, which reduces the levels of prostaglandins (inflammatory markers) and relieves the body of inflammation and pain.

    Why can’t I use S ETODOLAC for long-term management of pain?

    While S ETODOLAC is safe for treating acute pain, S ETODOLAC is not meant for long-term use because it can damage the kidneys and/or cause internal bleeding if over-used.

    Can S ETODOLAC be used for pain-relief during labour and delivery?

    No, S ETODOLAC is not indicated as a painkiller during labour and delivery as it may cause uterine bleeding.

    Available Medicines for

    S ETODOLAC