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సంఘటన :
TOFACITINIB-5MG
తయారీదారు/మార్కెటర్ :
Pfizer Ltd
వినియోగ రకం :
నోటి ద్వారా
రిటర్న్ పాలసీ :
తిరిగి ఇవ్వబడదు
ఇప్పటి నుండి గడువు ముగుస్తుంది :
Jan-27
Drug-Drug Interactions
TofacitinibStreptozocin
Severe
Drug-Drug Interactions
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How does the drug interact with Jakmac-ER Tablet:
Taking Jakmac-ER Tablet and Mercaptopurine increases the risk of infection.
How to manage the interaction:
Although there is a possible interaction between Mercaptopurine and Jakmac-ER Tablet, you can take these medicines together if prescribed by your doctor. If you experience any of these symptoms - serious infections, complications, fever, chills, diarrhea, sore throat, muscle pain, difficulty breathing, weight loss, or pain or burning when you pee - contact your doctor right away. Do not stop using any medications without talking to a doctor.
Taking Jakmac-ER Tablet and Mercaptopurine increases the risk of infection.
How to manage the interaction:
Although there is a possible interaction between Mercaptopurine and Jakmac-ER Tablet, you can take these medicines together if prescribed by your doctor. If you experience any of these symptoms - serious infections, complications, fever, chills, diarrhea, sore throat, muscle pain, difficulty breathing, weight loss, or pain or burning when you pee - contact your doctor right away. Do not stop using any medications without talking to a doctor.
TofacitinibStreptozocin
Severe
How does the drug interact with Jakmac-ER Tablet:
Taking Jakmac-ER Tablet with Streptozocin may increase the risk of infection.
How to manage the interaction:
Although taking Streptozocin and Jakmac-ER Tablet together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without consulting your doctor.
Taking Jakmac-ER Tablet with Streptozocin may increase the risk of infection.
How to manage the interaction:
Although taking Streptozocin and Jakmac-ER Tablet together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without consulting your doctor.
Severe
How does the drug interact with Jakmac-ER Tablet:
Taking carbamazepine and Jakmac-ER Tablet together may possibly reduce the blood levels of Jakmac-ER Tablet.
How to manage the interaction:
Although taking carbamazepine and Jakmac-ER Tablet together can possibly result in an interaction, it can be taken if your doctor has prescribed it. If your symptoms worsen or your condition changes while taking these medications, consult your doctor without delay.
Taking carbamazepine and Jakmac-ER Tablet together may possibly reduce the blood levels of Jakmac-ER Tablet.
How to manage the interaction:
Although taking carbamazepine and Jakmac-ER Tablet together can possibly result in an interaction, it can be taken if your doctor has prescribed it. If your symptoms worsen or your condition changes while taking these medications, consult your doctor without delay.
Severe
How does the drug interact with Jakmac-ER Tablet:
Combining Infliximab with Jakmac-ER Tablet can lead to or increase the risk or severity of developing serious infections.
How to manage the interaction:
Although taking Jakmac-ER Tablet and Infliximab together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience symptoms of fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in sputum, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Combining Infliximab with Jakmac-ER Tablet can lead to or increase the risk or severity of developing serious infections.
How to manage the interaction:
Although taking Jakmac-ER Tablet and Infliximab together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience symptoms of fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in sputum, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Severe
How does the drug interact with Jakmac-ER Tablet:
Taking Jakmac-ER Tablet with Dactinomycin may increase the risk of serious infection.
How to manage the interaction:
Taking Dactinomycin with Jakmac-ER Tablet together can possibly result in an interaction, but it can be taken if your doctor has advised it. If you experience any complications, infections, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, or pain or burning when you pee, make sure to call your doctor right away. Do not stop using any medications without first talking to your doctor.
Taking Jakmac-ER Tablet with Dactinomycin may increase the risk of serious infection.
How to manage the interaction:
Taking Dactinomycin with Jakmac-ER Tablet together can possibly result in an interaction, but it can be taken if your doctor has advised it. If you experience any complications, infections, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, or pain or burning when you pee, make sure to call your doctor right away. Do not stop using any medications without first talking to your doctor.
Severe
How does the drug interact with Jakmac-ER Tablet:
Taking Jakmac-ER Tablet with ritonavir may increase the blood levels of Jakmac-ER Tablet.
How to manage the interaction:
Although there is a possible interaction between Jakmac-ER Tablet and Ritonavir, but it can be taken together if prescribed by your doctor. However, consult your doctor if you experience fatigue, dizziness, fainting, fever, chills, loose stools, sore throat, muscle aches, shortness of breath, red or inflamed skin, body sores, and pain or burning during urination Do not stop using any medications without a doctor's advice.
Taking Jakmac-ER Tablet with ritonavir may increase the blood levels of Jakmac-ER Tablet.
How to manage the interaction:
Although there is a possible interaction between Jakmac-ER Tablet and Ritonavir, but it can be taken together if prescribed by your doctor. However, consult your doctor if you experience fatigue, dizziness, fainting, fever, chills, loose stools, sore throat, muscle aches, shortness of breath, red or inflamed skin, body sores, and pain or burning during urination Do not stop using any medications without a doctor's advice.
Severe
How does the drug interact with Jakmac-ER Tablet:
Taking Jakmac-ER Tablet with Doxorubicin may increase the risk of serious infection.
How to manage the interaction:
Although taking Jakmac-ER Tablet and Doxorubicin together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. It is important to keep a close eye on your condition. Do not stop using any medications without a doctor's advice.
Taking Jakmac-ER Tablet with Doxorubicin may increase the risk of serious infection.
How to manage the interaction:
Although taking Jakmac-ER Tablet and Doxorubicin together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. It is important to keep a close eye on your condition. Do not stop using any medications without a doctor's advice.
Severe
How does the drug interact with Jakmac-ER Tablet:
The use of Jakmac-ER Tablet with azathioprine may raise the risk of severe infections.
How to manage the interaction:
Co-administration of Azathioprine with Jakmac-ER Tablet can result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, and pain or burning during urination. Do not stop using any medications without a doctor's advice.
The use of Jakmac-ER Tablet with azathioprine may raise the risk of severe infections.
How to manage the interaction:
Co-administration of Azathioprine with Jakmac-ER Tablet can result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, and pain or burning during urination. Do not stop using any medications without a doctor's advice.
Severe
How does the drug interact with Jakmac-ER Tablet:
Taking Jakmac-ER Tablet together with lenalidomide may increase the risk of serious infections.
How to manage the interaction:
Although there is an interaction between lenalidomide and Jakmac-ER Tablet, it can be taken if prescribed by a doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, pain or burning during urination contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Taking Jakmac-ER Tablet together with lenalidomide may increase the risk of serious infections.
How to manage the interaction:
Although there is an interaction between lenalidomide and Jakmac-ER Tablet, it can be taken if prescribed by a doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, pain or burning during urination contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Jakmac-ER Tablet:
Taking Clarithromycin may boost the blood levels of Jakmac-ER Tablet, increasing side effects such as low blood cell count, anemia, serious infections, and elevated blood lipid levels.
How to manage the interaction:
Although there is a possible interaction, clarithromycin can be taken with Jakmac-ER Tablet if prescribed by the doctor. Consult the prescriber if you experience paleness, fatigue, dizziness, fainting, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without a doctor's advice.
Taking Clarithromycin may boost the blood levels of Jakmac-ER Tablet, increasing side effects such as low blood cell count, anemia, serious infections, and elevated blood lipid levels.
How to manage the interaction:
Although there is a possible interaction, clarithromycin can be taken with Jakmac-ER Tablet if prescribed by the doctor. Consult the prescriber if you experience paleness, fatigue, dizziness, fainting, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without a doctor's advice.
Drug-Food Interactions
TOFACITINIB-11MGGrapefruit and Grapefruit Juice
Moderate
Drug-Food Interactions
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TOFACITINIB-11MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit, Grapefruit Juice
How to manage the interaction:
Consuming grapefruit products while taking Jakmac-ER Tablet can increase the risk of side effects. Avoid consuming grapefruit products while being treated with Jakmac-ER Tablet, as it can lead to an interaction.
Grapefruit, Grapefruit Juice
How to manage the interaction:
Consuming grapefruit products while taking Jakmac-ER Tablet can increase the risk of side effects. Avoid consuming grapefruit products while being treated with Jakmac-ER Tablet, as it can lead to an interaction.
Product Substitutes
మద్యం
జాగ్రత్త
ఆల్కహాల్ Jakmac-ER Tablet 10'sతో సంకర్షణ చెందుతుందో లేదో తెలియదు, కాబట్టి దయచేసి వైద్యుడిని సంప్రదించండి.
గర్భం
అసురక్షితం
గర్భధారణ సమయంలో Jakmac-ER Tablet 10's తీసుకోకూడదు. మీరు గర్భం దాల్చే అవకాశం ఉన్న స్త్రీ అయితే, Jakmac-ER Tablet 10'sతో చికిత్స సమయంలో మరియు ఆపివేసిన 4 వారాల తర్వాత ప్రభావవంతమైన గర్భనిరోధకతను ఉపయోగించండి.
తల్లిపాలు ఇవ్వడం
అసురక్షితం
Jakmac-ER Tablet 10's తీసుకుంటున్నప్పుడు తల్లిపాలు ఇవ్వడం మానుకోండి. మీకు ఏవైనా సందేహాలు ఉంటే దయచేసి వైద్యుడిని సంప్రదించండి.
డ్రైవింగ్
సురక్షితం
సాధారణంగా Jakmac-ER Tablet 10's మీరు డ్రైవ్ చేసే సామర్థ్యాన్ని ప్రభావితం చేయదు. అయితే, మీరు అప్రమత్తంగా ఉంటే మాత్రమే డ్రైవ్ చేయండి లేదా యంత్రాలను నడపండి.
కాలేయం
జాగ్రత్త
కాలేయ బలహీనత ఉన్న రోగులలో మోతాదు సర్దుబాటు అవసరం కావచ్చు. మీకు కాలేయ బలహీనత లేదా దీనికి సంబంధించి ఏవైనా సందేహాలు ఉంటే దయచేసి మీ వైద్యుడిని సంప్రదించండి. తీవ్రమైన కాలేయ సమస్యలు ఉన్న రోగులకు Jakmac-ER Tablet 10's సిఫార్సు చేయబడలేదు.
కిడ్నీ
జాగ్రత్త
కిడ్నీ బలహీనత ఉన్న రోగులలో మోతాదు సర్దుబాటు అవసరం కావచ్చు. మీకు కిడ్నీ బలహీనత లేదా దీనికి సంబంధించి ఏవైనా సందేహాలు ఉంటే దయచేసి మీ వైద్యుడిని సంప్రదించండి.
పిల్లలు
అసురక్షితం
భద్రత మరియు ప్రభావం నిర్ధారించబడనందున 18 సంవత్సరాల కంటే తక్కువ వయస్సు ఉన్న పిల్లలకు Jakmac-ER Tablet 10's సిఫార్సు చేయబడలేదు.
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