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సంఘటన :
టోఫాసిటినిబ్-11ఎంజి
తయారీదారు/మార్కెటర్ :
ఎమ్క్యూర్ ఫార్మాస్యూటికల్స్ లిమిటెడ్
వినియోగ రకం :
నోటి ద్వారా
రిటర్న్ పాలసీ :
3 రోజుల్లో తిరిగి ఇవ్వవచ్చు
వీటి తర్వాత గడువు ముగుస్తుంది :
Jan-27
Drug-Drug Interactions
Severe
Severe
Drug-Drug Interactions
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Severe
How does the drug interact with Tobraza XR Tablet:
Coadministration of Ketoconazole and Tobraza XR Tablet may increase the blood levels and effects of Tobraza XR Tablet which may lead to side effects (low blood cell counts, anemia, serious infections, and elevated blood lipid levels).
How to manage the interaction:
Although taking Ketoconazole and Tobraza XR Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience symptoms like paleness, exhaustion, dizziness, fainting, fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in the phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning when urinating, consult a doctor. Do not stop using any medications without a doctor's advice.
Coadministration of Ketoconazole and Tobraza XR Tablet may increase the blood levels and effects of Tobraza XR Tablet which may lead to side effects (low blood cell counts, anemia, serious infections, and elevated blood lipid levels).
How to manage the interaction:
Although taking Ketoconazole and Tobraza XR Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience symptoms like paleness, exhaustion, dizziness, fainting, fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in the phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning when urinating, consult a doctor. Do not stop using any medications without a doctor's advice.
Severe
How does the drug interact with Tobraza XR Tablet:
Coadministration of methotrexate with Tobraza XR Tablet can increase the risk of developing serious infections.
How to manage the interaction:
Although there is a possible interaction between Tobraza XR Tablet and methotrexate, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, red or inflamed skin and pain or burning during urination, consult a doctor. Do not stop using any medications without consulting to a doctor.
Coadministration of methotrexate with Tobraza XR Tablet can increase the risk of developing serious infections.
How to manage the interaction:
Although there is a possible interaction between Tobraza XR Tablet and methotrexate, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, red or inflamed skin and pain or burning during urination, consult a doctor. Do not stop using any medications without consulting to a doctor.
Severe
How does the drug interact with Tobraza XR Tablet:
Taking Etanercept with Tobraza XR Tablet can increase the risk of serious infections as well as sometimes may lead to cancers.
How to manage the interaction:
Although there is a possible interaction between Tobraza XR Tablet and Etanercept, you can take these medicines together if prescribed by a doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not stop using any medications without talking to a doctor.
Taking Etanercept with Tobraza XR Tablet can increase the risk of serious infections as well as sometimes may lead to cancers.
How to manage the interaction:
Although there is a possible interaction between Tobraza XR Tablet and Etanercept, you can take these medicines together if prescribed by a doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not stop using any medications without talking to a doctor.
TofacitinibBoceprevir
Severe
How does the drug interact with Tobraza XR Tablet:
Taking Tobraza XR Tablet with Boceprevir may increases the blood levels of Tobraza XR Tablet which increases risk of side effects.
How to manage the interaction:
There may be a possibility of interaction between Tobraza XR Tablet and Boceprevir, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience fatigue, dizziness, fainting, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without consulting your doctor.
Taking Tobraza XR Tablet with Boceprevir may increases the blood levels of Tobraza XR Tablet which increases risk of side effects.
How to manage the interaction:
There may be a possibility of interaction between Tobraza XR Tablet and Boceprevir, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience fatigue, dizziness, fainting, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without consulting your doctor.
Severe
How does the drug interact with Tobraza XR Tablet:
Taking Carfilzomib with Tobraza XR Tablet may increase the risk of serious infections.
How to manage the interaction:
Co-administration of Tobraza XR Tablet with Carfilzomib can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without first consulting your doctor.
Taking Carfilzomib with Tobraza XR Tablet may increase the risk of serious infections.
How to manage the interaction:
Co-administration of Tobraza XR Tablet with Carfilzomib can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without first consulting your doctor.
TofacitinibEnzalutamide
Severe
How does the drug interact with Tobraza XR Tablet:
Co-administration of Enzalutamide and Tobraza XR Tablet may decrease the blood levels of Tobraza XR Tablet, which may make Tobraza XR Tablet less effective.
How to manage the interaction:
Although taking Enzalutamide and Tobraza XR Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. Do not stop using any medications without consulting a doctor.
Co-administration of Enzalutamide and Tobraza XR Tablet may decrease the blood levels of Tobraza XR Tablet, which may make Tobraza XR Tablet less effective.
How to manage the interaction:
Although taking Enzalutamide and Tobraza XR Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. Do not stop using any medications without consulting a doctor.
Severe
How does the drug interact with Tobraza XR Tablet:
Taking Tobraza XR Tablet with Docetaxel may increase the risk of infection.
How to manage the interaction:
Although there is a possible interaction between Tobraza XR Tablet and Docetaxel, you can take these medicines together if prescribed by your doctor. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without first talking to your doctor.
Taking Tobraza XR Tablet with Docetaxel may increase the risk of infection.
How to manage the interaction:
Although there is a possible interaction between Tobraza XR Tablet and Docetaxel, you can take these medicines together if prescribed by your doctor. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without first talking to your doctor.
Severe
How does the drug interact with Tobraza XR Tablet:
Combining Infliximab with Tobraza XR Tablet can lead to or increase the risk or severity of developing serious infections.
How to manage the interaction:
Although taking Tobraza XR Tablet and Infliximab together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience symptoms of fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in sputum, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Combining Infliximab with Tobraza XR Tablet can lead to or increase the risk or severity of developing serious infections.
How to manage the interaction:
Although taking Tobraza XR Tablet and Infliximab together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience symptoms of fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in sputum, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Tobraza XR Tablet:
Taking Tobraza XR Tablet and Mercaptopurine increases the risk of infection.
How to manage the interaction:
Although there is a possible interaction between Mercaptopurine and Tobraza XR Tablet, you can take these medicines together if prescribed by your doctor. If you experience any of these symptoms - serious infections, complications, fever, chills, diarrhea, sore throat, muscle pain, difficulty breathing, weight loss, or pain or burning when you pee - contact your doctor right away. Do not stop using any medications without talking to a doctor.
Taking Tobraza XR Tablet and Mercaptopurine increases the risk of infection.
How to manage the interaction:
Although there is a possible interaction between Mercaptopurine and Tobraza XR Tablet, you can take these medicines together if prescribed by your doctor. If you experience any of these symptoms - serious infections, complications, fever, chills, diarrhea, sore throat, muscle pain, difficulty breathing, weight loss, or pain or burning when you pee - contact your doctor right away. Do not stop using any medications without talking to a doctor.
Severe
How does the drug interact with Tobraza XR Tablet:
Taking Tobraza XR Tablet with Nilotinib may increase the risk of infections.
How to manage the interaction:
Although there is a possible interaction between Tobraza XR Tablet and Nilotinib, you can take these medicines together if prescribed by your doctor. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without a doctor's advice.
Taking Tobraza XR Tablet with Nilotinib may increase the risk of infections.
How to manage the interaction:
Although there is a possible interaction between Tobraza XR Tablet and Nilotinib, you can take these medicines together if prescribed by your doctor. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without a doctor's advice.
Drug-Food Interactions
TOFACITINIB-11MGGrapefruit and Grapefruit Juice
Moderate
Drug-Food Interactions
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TOFACITINIB-11MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit, Grapefruit Juice
How to manage the interaction:
Consuming grapefruit products while taking Tobraza XR Tablet can increase the risk of side effects. Avoid consuming grapefruit products while being treated with Tobraza XR Tablet, as it can lead to an interaction.
Grapefruit, Grapefruit Juice
How to manage the interaction:
Consuming grapefruit products while taking Tobraza XR Tablet can increase the risk of side effects. Avoid consuming grapefruit products while being treated with Tobraza XR Tablet, as it can lead to an interaction.
Product Substitutes
మద్యం
జాగ్రత్త
ఆల్కహాల్ Tobraza XR Tablet 10'sతో సంకర్షణ చెందుతుందో లేదో తెలియదు, కాబట్టి దయచేసి వైద్యుడిని సంప్రదించండి.
గర్భం
అసురక్షితం
గర్భధారణ సమయంలో Tobraza XR Tablet 10's తీసుకోకూడదు. మీరు గర్భం దాల్చే అవకాశం ఉన్న స్త్రీ అయితే, Tobraza XR Tablet 10'sతో చికిత్స సమయంలో మరియు ఆపివేసిన 4 వారాల తర్వాత సమర్థవంతమైన గర్భనిరోధకతను ఉపయోగించండి.
తల్లిపాలు ఇవ్వడం
అసురక్షితం
Tobraza XR Tablet 10's తీసుకుంటున్నప్పుడు తల్లిపాలు ఇవ్వడం మానుకోండి. మీకు ఏవైనా సందేహాలు ఉంటే దయచేసి వైద్యుడిని సంప్రదించండి.
డ్రైవింగ్
సురక్షితం
సాధారణంగా Tobraza XR Tablet 10's మీ డ్రైవింగ్ సామర్థ్యాన్ని ప్రభావితం చేయదు. అయితే, మీరు అప్రమత్తంగా ఉన్నప్పుడు మాత్రమే డ్రైవ్ చేయండి లేదా యంత్రాలను ఆపరేట్ చేయండి.
లివర్
జాగ్రత్త
కాలేయ బలహీనత ఉన్న రోగులలో మోతాదు సర్దుబాటు అవసరం కావచ్చు. మీకు కాలేయ బలహీనత లేదా దీనికి సంబంధించి ఏవైనా సందేహాలు ఉంటే దయచేసి మీ వైద్యుడిని సంప్రదించండి. తీవ్రమైన కాలేయ సమస్యలు ఉన్న రోగులకు Tobraza XR Tablet 10's సిఫారసు చేయబడలేదు.
కిడ్నీ
జాగ్రత్త
కిడ్నీ బలహీనత ఉన్న రోగులలో మోతాదు సర్దుబాటు అవసరం కావచ్చు. మీకు కిడ్నీ బలహీనత లేదా దీనికి సంబంధించి ఏవైనా సందేహాలు ఉంటే దయచేసి మీ వైద్యుడిని సంప్రదించండి.
పిల్లలు
అసురక్షితం
భద్రత మరియు ప్రభావం నిర్ధారించబడనందున 18 సంవత్సరాల కంటే తక్కువ వయస్సు ఉన్న పిల్లలకు Tobraza XR Tablet 10's సిఫారసు చేయబడలేదు.
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