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సంఘటన :
టోఫాసిటినిబ్-11ఎంజి
తయారీదారు/మార్కెటర్ :
ఎమ్క్యూర్ ఫార్మాస్యూటికల్స్ లిమిటెడ్
వినియోగ రకం :
నోటి ద్వారా
రిటర్న్ పాలసీ :
3 రోజుల్లో తిరిగి ఇవ్వవచ్చు
వీటి తర్వాత గడువు ముగుస్తుంది :
Jan-27
Drug-Drug Interactions
Severe
Severe
Drug-Drug Interactions
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Severe
How does the drug interact with Tofajak XR Tablet:
Taking Tofajak XR Tablet with atazanavir may increase the blood levels of Tofajak XR Tablet. This may lead to cause severe infections.
How to manage the interaction:
Co-administration of Tofajak XR Tablet with Atazanavir can possibly result in an interaction, but it can be taken if your doctor has advised it. However consult your doctor if you experience fatigue, dizziness, fainting, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without talking to your doctor.
Taking Tofajak XR Tablet with atazanavir may increase the blood levels of Tofajak XR Tablet. This may lead to cause severe infections.
How to manage the interaction:
Co-administration of Tofajak XR Tablet with Atazanavir can possibly result in an interaction, but it can be taken if your doctor has advised it. However consult your doctor if you experience fatigue, dizziness, fainting, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without talking to your doctor.
Severe
How does the drug interact with Tofajak XR Tablet:
Taking tacrolimus together with Tofajak XR Tablet may increase the risk of serious infections.
How to manage the interaction:
Although taking tacrolimus and Tofajak XR Tablet together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without consulting doctor.
Taking tacrolimus together with Tofajak XR Tablet may increase the risk of serious infections.
How to manage the interaction:
Although taking tacrolimus and Tofajak XR Tablet together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without consulting doctor.
Severe
How does the drug interact with Tofajak XR Tablet:
Using Tofajak XR Tablet together with dasatinib may increase the risk of serious infections.
How to manage the interaction:
Co-administration of Tofajak XR Tablet with Dasatinib can result in an interaction, but it can be taken if a doctor has advised it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without consulting a doctor.
Using Tofajak XR Tablet together with dasatinib may increase the risk of serious infections.
How to manage the interaction:
Co-administration of Tofajak XR Tablet with Dasatinib can result in an interaction, but it can be taken if a doctor has advised it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Tofajak XR Tablet:
Taking Cyclophosphamide with Tofajak XR Tablet may increase the risk of serious infections.
How to manage the interaction:
Although there is a possible interaction, Cyclophosphamide can be taken with Tofajak XR Tablet if prescribed by the doctor. Consult the doctor immediately if you develop signs and symptoms of infection such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue the medication without consulting a doctor.
Taking Cyclophosphamide with Tofajak XR Tablet may increase the risk of serious infections.
How to manage the interaction:
Although there is a possible interaction, Cyclophosphamide can be taken with Tofajak XR Tablet if prescribed by the doctor. Consult the doctor immediately if you develop signs and symptoms of infection such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue the medication without consulting a doctor.
Severe
How does the drug interact with Tofajak XR Tablet:
Using Tofajak XR Tablet together with phenytoin may reduce the blood levels and effects of Tofajak XR Tablet.
How to manage the interaction:
Taking Tofajak XR Tablet with Phenytoin together can result in an interaction, but it can be taken if your doctor has advised it. Doctors can recommend other options that won't cause any problems when taken together. Do not stop using any medications without talking to a doctor.
Using Tofajak XR Tablet together with phenytoin may reduce the blood levels and effects of Tofajak XR Tablet.
How to manage the interaction:
Taking Tofajak XR Tablet with Phenytoin together can result in an interaction, but it can be taken if your doctor has advised it. Doctors can recommend other options that won't cause any problems when taken together. Do not stop using any medications without talking to a doctor.
TofacitinibAntithymocyte Globulin
Severe
How does the drug interact with Tofajak XR Tablet:
Using Tofajak XR Tablet together with antithymocyte globulin can increase the risk of serious infections.
How to manage the interaction:
Taking Antithymocyte Globulin with Tofajak XR Tablet together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, pain or burning during urination contact your doctor. Do not discontinue any medications without consulting your doctor.
Using Tofajak XR Tablet together with antithymocyte globulin can increase the risk of serious infections.
How to manage the interaction:
Taking Antithymocyte Globulin with Tofajak XR Tablet together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, pain or burning during urination contact your doctor. Do not discontinue any medications without consulting your doctor.
TofacitinibEnzalutamide
Severe
How does the drug interact with Tofajak XR Tablet:
Co-administration of Enzalutamide and Tofajak XR Tablet may decrease the blood levels of Tofajak XR Tablet, which may make Tofajak XR Tablet less effective.
How to manage the interaction:
Although taking Enzalutamide and Tofajak XR Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. Do not stop using any medications without consulting a doctor.
Co-administration of Enzalutamide and Tofajak XR Tablet may decrease the blood levels of Tofajak XR Tablet, which may make Tofajak XR Tablet less effective.
How to manage the interaction:
Although taking Enzalutamide and Tofajak XR Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. Do not stop using any medications without consulting a doctor.
Severe
How does the drug interact with Tofajak XR Tablet:
Taking Tofajak XR Tablet with Doxorubicin may increase the risk of serious infection.
How to manage the interaction:
Although taking Tofajak XR Tablet and Doxorubicin together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. It is important to keep a close eye on your condition. Do not stop using any medications without a doctor's advice.
Taking Tofajak XR Tablet with Doxorubicin may increase the risk of serious infection.
How to manage the interaction:
Although taking Tofajak XR Tablet and Doxorubicin together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. It is important to keep a close eye on your condition. Do not stop using any medications without a doctor's advice.
TofacitinibBasiliximab
Severe
How does the drug interact with Tofajak XR Tablet:
Basiliximab can enhance the immune-suppressing effects of Tofajak XR Tablet which increases risk of infections.
How to manage the interaction:
There may be a possibility of interaction between Tofajak XR Tablet and Basiliximab, but it can be taken if prescribed by a doctor. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without first consulting your doctor.
Basiliximab can enhance the immune-suppressing effects of Tofajak XR Tablet which increases risk of infections.
How to manage the interaction:
There may be a possibility of interaction between Tofajak XR Tablet and Basiliximab, but it can be taken if prescribed by a doctor. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without first consulting your doctor.
How does the drug interact with Tofajak XR Tablet:
Taking Clarithromycin may boost the blood levels of Tofajak XR Tablet, increasing side effects such as low blood cell count, anemia, serious infections, and elevated blood lipid levels.
How to manage the interaction:
Although there is a possible interaction, clarithromycin can be taken with Tofajak XR Tablet if prescribed by the doctor. Consult the prescriber if you experience paleness, fatigue, dizziness, fainting, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without a doctor's advice.
Taking Clarithromycin may boost the blood levels of Tofajak XR Tablet, increasing side effects such as low blood cell count, anemia, serious infections, and elevated blood lipid levels.
How to manage the interaction:
Although there is a possible interaction, clarithromycin can be taken with Tofajak XR Tablet if prescribed by the doctor. Consult the prescriber if you experience paleness, fatigue, dizziness, fainting, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without a doctor's advice.
Drug-Food Interactions
TOFACITINIB-11MGGrapefruit and Grapefruit Juice
Moderate
Drug-Food Interactions
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TOFACITINIB-11MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit, Grapefruit Juice
How to manage the interaction:
Consuming grapefruit products while taking Tofajak XR Tablet can increase the risk of side effects. Avoid consuming grapefruit products while being treated with Tofajak XR Tablet, as it can lead to an interaction.
Grapefruit, Grapefruit Juice
How to manage the interaction:
Consuming grapefruit products while taking Tofajak XR Tablet can increase the risk of side effects. Avoid consuming grapefruit products while being treated with Tofajak XR Tablet, as it can lead to an interaction.
Product Substitutes
మద్యం
జాగ్రత్త
ఆల్కహాల్ Tofajak XR Tablet 10'sతో సంకర్షణ చెందుతుందో లేదో తెలియదు, కాబట్టి దయచేసి వైద్యుడిని సంప్రదించండి.
గర్భం
అసురక్షితం
గర్భధారణ సమయంలో Tofajak XR Tablet 10's తీసుకోకూడదు. మీరు గర్భం దాల్చే అవకాశం ఉన్న స్త్రీ అయితే, Tofajak XR Tablet 10'sతో చికిత్స సమయంలో మరియు ఆపివేసిన 4 వారాల తర్వాత సమర్థవంతమైన గర్భనిరోధకతను ఉపయోగించండి.
తల్లిపాలు ఇవ్వడం
అసురక్షితం
Tofajak XR Tablet 10's తీసుకుంటున్నప్పుడు తల్లిపాలు ఇవ్వడం మానుకోండి. మీకు ఏవైనా సందేహాలు ఉంటే దయచేసి వైద్యుడిని సంప్రదించండి.
డ్రైవింగ్
సురక్షితం
సాధారణంగా Tofajak XR Tablet 10's మీ డ్రైవింగ్ సామర్థ్యాన్ని ప్రభావితం చేయదు. అయితే, మీరు అప్రమత్తంగా ఉన్నప్పుడు మాత్రమే డ్రైవ్ చేయండి లేదా యంత్రాలను ఆపరేట్ చేయండి.
లివర్
జాగ్రత్త
కాలేయ బలహీనత ఉన్న రోగులలో మోతాదు సర్దుబాటు అవసరం కావచ్చు. మీకు కాలేయ బలహీనత లేదా దీనికి సంబంధించి ఏవైనా సందేహాలు ఉంటే దయచేసి మీ వైద్యుడిని సంప్రదించండి. తీవ్రమైన కాలేయ సమస్యలు ఉన్న రోగులకు Tofajak XR Tablet 10's సిఫారసు చేయబడలేదు.
కిడ్నీ
జాగ్రత్త
కిడ్నీ బలహీనత ఉన్న రోగులలో మోతాదు సర్దుబాటు అవసరం కావచ్చు. మీకు కిడ్నీ బలహీనత లేదా దీనికి సంబంధించి ఏవైనా సందేహాలు ఉంటే దయచేసి మీ వైద్యుడిని సంప్రదించండి.
పిల్లలు
అసురక్షితం
భద్రత మరియు ప్రభావం నిర్ధారించబడనందున 18 సంవత్సరాల కంటే తక్కువ వయస్సు ఉన్న పిల్లలకు Tofajak XR Tablet 10's సిఫారసు చేయబడలేదు.
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