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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Justnow 5mg Tablet is used to treat heavy, painful, or irregular periods, premenstrual syndrome (PMS), and endometriosis. Additionally, it may be used in the treatment of breast cancer. It contains Norethisterone which works by restoring the hormone levels in the body. In some cases, this medicine may cause side effects such as unusual vaginal bleeding or spotting, dizziness, dry mouth, constipation, nausea, and diarrhoea. Let the doctor know if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Drug-Drug Interactions

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NorethisteroneTelaprevir
Severe

Drug-Drug Interactions

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How does the drug interact with Justnow 5mg Tablet:
Coadministration of Justnow 5mg Tablet with Tizanidine can cause drowsiness, confusion, slow heart rate, shallow breathing, feeling light-headed, fainting.

How to manage the interaction:
Taking Justnow 5mg Tablet with Tizanidine together can result in an interaction, but it can be taken if your doctor has advised it. However, if you notice any symptoms, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
NorethisteroneTelaprevir
Severe
How does the drug interact with Justnow 5mg Tablet:
Using Telaprevir and Justnow 5mg Tablet together can increase risk of unintended pregnancy and decrease the effectiveness of norethindrone.

How to manage the interaction:
Combining Telaprevir with Justnow 5mg Tablet can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience any symptoms like increased hot flashes, vaginal dryness, or menstrual abnormalities, contact the doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Justnow 5mg Tablet:
Coadministration of Justnow 5mg Tablet with Oxcarbazepine can reduce the blood levels and effects of norethindrone. This increases the risk of severe bleeding and unintended pregnancy.

How to manage the interaction:
Although taking oxcarbazepine and Justnow 5mg Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. If you experience any symptoms like abnormal bleeding, consult the doctor immediately Do not discontinue any medications without consulting a doctor.
How does the drug interact with Justnow 5mg Tablet:
Eslicarbazepine may reduce the effects of Justnow 5mg Tablet and its blood levels.

How to manage the interaction:
Although taking Eslicarbazepine and Justnow 5mg Tablet results in an interaction, they can be taken together if prescribed by your doctor. Do not stop using any medications without consulting a doctor.
How does the drug interact with Justnow 5mg Tablet:
Co-administration of Justnow 5mg Tablet with Bosentan can reduce the blood levels and effects of norethindrone.

How to manage the interaction:
Taking Justnow 5mg Tablet with Bosentan together can result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without talking to a doctor.
How does the drug interact with Justnow 5mg Tablet:
Coadministration of Justnow 5mg Tablet with Rifabutin can reduce the blood levels and effects of norethindrone.This increases the risk of severe bleeding and unintended pregnancy.

How to manage the interaction:
Taking Justnow 5mg Tablet with Rifabutin together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any symptoms of abnormal bleeding, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
Severe
How does the drug interact with Justnow 5mg Tablet:
Using Felbamate and Justnow 5mg Tablet together can reduce the blood levels and effects of norethindrone.

How to manage the interaction:
There may be a possibility of interaction between Justnow 5mg Tablet and Felbamate, but it can be taken if prescribed by a doctor. If you notice any unusual symptoms like changes in your menstrual cycle, excessive bleeding, make sure to contact a doctor right away. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Justnow 5mg Tablet:
Using tranexamic acid together with norethindrone may increase the risk of blood clots.

How to manage the interaction:
Taking Justnow 5mg Tablet with tranexamic acid can lead to an interaction, however, it can be taken only if a doctor has advised it. If you experience symptoms such as chest pain, shortness of breath, coughing up blood, blood in the urine, sudden loss of vision, and pain, redness, or swelling in your arm or leg, contact a doctor immediately .Do not discontinue any medications without consulting a doctor.
NorethisteroneFosamprenavir
Severe
How does the drug interact with Justnow 5mg Tablet:
Using norethindrone together with fosamprenavir may decrease the effects of fosamprenavir.

How to manage the interaction:
Taking Justnow 5mg Tablet with Fosamprenavir together can result in an interaction, but it can be taken if your doctor has advised it. If you're taking birth control and experiencing any symptoms, it's important to reach out to a doctor right away. They can recommend other options that won't interfere with your medication. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Justnow 5mg Tablet:
Coadministration of Acitretin with Justnow 5mg Tablet may interfere with the contraceptive effect of Justnow 5mg Tablet.

How to manage the interaction:
Acitretin and Justnow 5mg Tablet should be used together only if prescribed by your doctor. Use of at least two methods of effective contraception is mandatory during acitretin therapy and for at least 3 years after stopping therapy.

Drug-Food Interactions

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NORETHISTERONE-5MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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NORETHISTERONE-5MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice

How to manage the interaction:
Consuming Grapefruit juice may increase the blood levels of Justnow 5mg Tablet. Avoid or limit the consumption of grapefruit and grapefruit juice while taking the Justnow 5mg Tablet dose. Avoid or limit the consumption of grapefruit and grapefruit juice while taking the Justnow 5mg Tablet dose.

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