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సంఘటన :
టోఫాసిటినిబ్-11ఎంజి
తయారీదారు/మార్కెటర్ :
ఎమ్క్యూర్ ఫార్మాస్యూటికల్స్ లిమిటెడ్
వినియోగ రకం :
నోటి ద్వారా
రిటర్న్ పాలసీ :
3 రోజుల్లో తిరిగి ఇవ్వవచ్చు
వీటి తర్వాత గడువు ముగుస్తుంది :
Jan-27
Drug-Drug Interactions
Severe
Severe
Drug-Drug Interactions
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Severe
How does the drug interact with Flexjak ER Tablet:
Taking Flexjak ER Tablet with Docetaxel may increase the risk of infection.
How to manage the interaction:
Although there is a possible interaction between Flexjak ER Tablet and Docetaxel, you can take these medicines together if prescribed by your doctor. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without first talking to your doctor.
Taking Flexjak ER Tablet with Docetaxel may increase the risk of infection.
How to manage the interaction:
Although there is a possible interaction between Flexjak ER Tablet and Docetaxel, you can take these medicines together if prescribed by your doctor. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without first talking to your doctor.
Severe
How does the drug interact with Flexjak ER Tablet:
Taking Flexjak ER Tablet with Temsirolimus may increase the risk of infection.
How to manage the interaction:
Although there is a possible interaction between Flexjak ER Tablet and Temsirolimus, you can take these medicines together if prescribed by your doctor. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without consulting your doctor.
Taking Flexjak ER Tablet with Temsirolimus may increase the risk of infection.
How to manage the interaction:
Although there is a possible interaction between Flexjak ER Tablet and Temsirolimus, you can take these medicines together if prescribed by your doctor. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Flexjak ER Tablet:
Coadministration of Mycophenolic acid and Flexjak ER Tablet can increase the risk or severity of developing serious infections
How to manage the interaction:
Taking Mycophenolic acid and Flexjak ER Tablet together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience fever, chills, diarrhoea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination consult a doctor. Do not discontinue any medications without a doctor's advice.
Coadministration of Mycophenolic acid and Flexjak ER Tablet can increase the risk or severity of developing serious infections
How to manage the interaction:
Taking Mycophenolic acid and Flexjak ER Tablet together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience fever, chills, diarrhoea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination consult a doctor. Do not discontinue any medications without a doctor's advice.
Severe
How does the drug interact with Flexjak ER Tablet:
Taking Ceritinib with Flexjak ER Tablet may increase the risk of side effects.
How to manage the interaction:
Although there is a possible interaction between Ceritinib and Flexjak ER Tablet, you can take these medicines together if prescribed by your doctor. If you notice any symptoms like feeling tired, dizzy, or faint, or if you have a fever, diarrhea, or difficulty breathing, it is important to contact a doctor. Do not discontinue any medications without consulting a doctor.
Taking Ceritinib with Flexjak ER Tablet may increase the risk of side effects.
How to manage the interaction:
Although there is a possible interaction between Ceritinib and Flexjak ER Tablet, you can take these medicines together if prescribed by your doctor. If you notice any symptoms like feeling tired, dizzy, or faint, or if you have a fever, diarrhea, or difficulty breathing, it is important to contact a doctor. Do not discontinue any medications without consulting a doctor.
Severe
How does the drug interact with Flexjak ER Tablet:
When Flexjak ER Tablet and Olaparib are taken together, the breakdown of Flexjak ER Tablet in the body may be reduced.
How to manage the interaction:
Although there is a possible interaction between Olaparib and Flexjak ER Tablet, you can take these medicines together if prescribed by your doctor. It's better to be safe and get medical help if you have a fever, chills, diarrhea, sore throat, muscle aches, trouble breathing, weight loss, or pain while urinating. Do not stop using any medications without first talking to your doctor.
When Flexjak ER Tablet and Olaparib are taken together, the breakdown of Flexjak ER Tablet in the body may be reduced.
How to manage the interaction:
Although there is a possible interaction between Olaparib and Flexjak ER Tablet, you can take these medicines together if prescribed by your doctor. It's better to be safe and get medical help if you have a fever, chills, diarrhea, sore throat, muscle aches, trouble breathing, weight loss, or pain while urinating. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Flexjak ER Tablet:
Taking Flexjak ER Tablet and Mercaptopurine increases the risk of infection.
How to manage the interaction:
Although there is a possible interaction between Mercaptopurine and Flexjak ER Tablet, you can take these medicines together if prescribed by your doctor. If you experience any of these symptoms - serious infections, complications, fever, chills, diarrhea, sore throat, muscle pain, difficulty breathing, weight loss, or pain or burning when you pee - contact your doctor right away. Do not stop using any medications without talking to a doctor.
Taking Flexjak ER Tablet and Mercaptopurine increases the risk of infection.
How to manage the interaction:
Although there is a possible interaction between Mercaptopurine and Flexjak ER Tablet, you can take these medicines together if prescribed by your doctor. If you experience any of these symptoms - serious infections, complications, fever, chills, diarrhea, sore throat, muscle pain, difficulty breathing, weight loss, or pain or burning when you pee - contact your doctor right away. Do not stop using any medications without talking to a doctor.
How does the drug interact with Flexjak ER Tablet:
Taking Clarithromycin may boost the blood levels of Flexjak ER Tablet, increasing side effects such as low blood cell count, anemia, serious infections, and elevated blood lipid levels.
How to manage the interaction:
Although there is a possible interaction, clarithromycin can be taken with Flexjak ER Tablet if prescribed by the doctor. Consult the prescriber if you experience paleness, fatigue, dizziness, fainting, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without a doctor's advice.
Taking Clarithromycin may boost the blood levels of Flexjak ER Tablet, increasing side effects such as low blood cell count, anemia, serious infections, and elevated blood lipid levels.
How to manage the interaction:
Although there is a possible interaction, clarithromycin can be taken with Flexjak ER Tablet if prescribed by the doctor. Consult the prescriber if you experience paleness, fatigue, dizziness, fainting, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without a doctor's advice.
Severe
How does the drug interact with Flexjak ER Tablet:
When Flexjak ER Tablet and Clozapine are taken together, that may increase the risk of severe infections.
How to manage the interaction:
There may be a possibility of interaction between Flexjak ER Tablet and Clozapine, but it can be taken if prescribed by a doctor. Your doctor can recommend other options that won't cause problems when taken together. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without first talking to your doctor.
When Flexjak ER Tablet and Clozapine are taken together, that may increase the risk of severe infections.
How to manage the interaction:
There may be a possibility of interaction between Flexjak ER Tablet and Clozapine, but it can be taken if prescribed by a doctor. Your doctor can recommend other options that won't cause problems when taken together. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without first talking to your doctor.
Severe
How does the drug interact with Flexjak ER Tablet:
Coadministration of methotrexate with Flexjak ER Tablet can increase the risk of developing serious infections.
How to manage the interaction:
Although there is a possible interaction between Flexjak ER Tablet and methotrexate, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, red or inflamed skin and pain or burning during urination, consult a doctor. Do not stop using any medications without consulting to a doctor.
Coadministration of methotrexate with Flexjak ER Tablet can increase the risk of developing serious infections.
How to manage the interaction:
Although there is a possible interaction between Flexjak ER Tablet and methotrexate, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, red or inflamed skin and pain or burning during urination, consult a doctor. Do not stop using any medications without consulting to a doctor.
Severe
How does the drug interact with Flexjak ER Tablet:
Taking Flexjak ER Tablet with Thiotepa may increase the risk of infection.
How to manage the interaction:
Co-administration of Thiotepa with Flexjak ER Tablet can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without a doctor's advice.
Taking Flexjak ER Tablet with Thiotepa may increase the risk of infection.
How to manage the interaction:
Co-administration of Thiotepa with Flexjak ER Tablet can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without a doctor's advice.
Drug-Food Interactions
TOFACITINIB-11MGGrapefruit and Grapefruit Juice
Moderate
Drug-Food Interactions
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TOFACITINIB-11MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit, Grapefruit Juice
How to manage the interaction:
Consuming grapefruit products while taking Flexjak ER Tablet can increase the risk of side effects. Avoid consuming grapefruit products while being treated with Flexjak ER Tablet, as it can lead to an interaction.
Grapefruit, Grapefruit Juice
How to manage the interaction:
Consuming grapefruit products while taking Flexjak ER Tablet can increase the risk of side effects. Avoid consuming grapefruit products while being treated with Flexjak ER Tablet, as it can lead to an interaction.
Product Substitutes
మద్యం
జాగ్రత్త
ఆల్కహాల్ ఫ్లెక్స్జాక్ ER టాబ్లెట్ 10'sతో సంకర్షణ చెందుతుందో లేదో తెలియదు, కాబట్టి దయచేసి వైద్యుడిని సంప్రదించండి.
గర్భం
అసురక్షితం
గర్భధారణ సమయంలో ఫ్లెక్స్జాక్ ER టాబ్లెట్ 10's తీసుకోకూడదు. మీరు గర్భం దాల్చే అవకాశం ఉన్న స్త్రీ అయితే, ఫ్లెక్స్జాక్ ER టాబ్లెట్ 10'sతో చికిత్స సమయంలో మరియు ఆపివేసిన 4 వారాల తర్వాత సమర్థవంతమైన గర్భనిరోధకతను ఉపయోగించండి.
తల్లిపాలు ఇవ్వడం
అసురక్షితం
ఫ్లెక్స్జాక్ ER టాబ్లెట్ 10's తీసుకుంటున్నప్పుడు తల్లిపాలు ఇవ్వడం మానుకోండి. మీకు ఏవైనా సందేహాలు ఉంటే దయచేసి వైద్యుడిని సంప్రదించండి.
డ్రైవింగ్
సురక్షితం
సాధారణంగా ఫ్లెక్స్జాక్ ER టాబ్లెట్ 10's మీ డ్రైవింగ్ సామర్థ్యాన్ని ప్రభావితం చేయదు. అయితే, మీరు అప్రమత్తంగా ఉన్నప్పుడు మాత్రమే డ్రైవ్ చేయండి లేదా యంత్రాలను ఆపరేట్ చేయండి.
లివర్
జాగ్రత్త
కాలేయ బలహీనత ఉన్న రోగులలో మోతాదు సర్దుబాటు అవసరం కావచ్చు. మీకు కాలేయ బలహీనత లేదా దీనికి సంబంధించి ఏవైనా సందేహాలు ఉంటే దయచేసి మీ వైద్యుడిని సంప్రదించండి. తీవ్రమైన కాలేయ సమస్యలు ఉన్న రోగులకు ఫ్లెక్స్జాక్ ER టాబ్లెట్ 10's సిఫారసు చేయబడలేదు.
కిడ్నీ
జాగ్రత్త
కిడ్నీ బలహీనత ఉన్న రోగులలో మోతాదు సర్దుబాటు అవసరం కావచ్చు. మీకు కిడ్నీ బలహీనత లేదా దీనికి సంబంధించి ఏవైనా సందేహాలు ఉంటే దయచేసి మీ వైద్యుడిని సంప్రదించండి.
పిల్లలు
అసురక్షితం
భద్రత మరియు ప్రభావం నిర్ధారించబడనందున 18 సంవత్సరాల కంటే తక్కువ వయస్సు ఉన్న పిల్లలకు ఫ్లెక్స్జాక్ ER టాబ్లెట్ 10's సిఫారసు చేయబడలేదు.
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