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Naxdom 500 Tablet is used to treat migraine headaches. Additionally, it can also be used to alleviate pain associated with rheumatoid arthritis, gout, and dysmenorrhea (menstrual pain). It contains Naproxen and Domperidone, which work by reducing certain chemical substances (prostaglandins) that cause pain and swelling. Also, it prevents nausea and vomiting symptoms by blocking certain receptors (like dopamine and serotonin) that stimulate the vomiting centre in the brain. It may cause common side effects, such as dry mouth, abdominal pain, constipation, drowsiness, dizziness, visual disturbances, hearing problems, and headache. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Lakshmithulasi Yarragunta ,
Reviewed By Veda Maddala , M Pharmacy
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Drug-Drug Interactions

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Drug-drug interactions: Naxdom 500 Tablet may interact with other NSAIDs (such as ketorolac), anticoagulants (such as warfarin), corticosteroids (such as prednisolone), anti-hypertensive medications (such as ramipril and amlodipine), antibiotics (such as amikacin), lipid-lowering drugs (such as atorvastatin), and antidepressants (such as citalopram and fluoxetine).

Drug-food interactions: No interactions found.

Drug-disease interactions: Patients with peptic ulcers, inflammatory bowel disease (inflammation of the digestive tract), liver diseases, kidney diseases, heart problems, and respiratory diseases should take the Naxdom 500 Tablet only when prescribed by a doctor.

Drug-Drug Interactions

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How does the drug interact with Naxdom 500 Tablet:
Co-administration of Naxdom 500 Tablet with Meloxicam can increase the risk or severity of side effects (gastric bleeding, ulceration, and rarely, perforation leading to serious blood loss).

How to manage the interaction:
Taking Meloxicam with Naxdom 500 Tablet is not advised as it can result in an interaction, it can be taken if a doctor has advised it. You should seek immediate medical attention if you experience any unusual bleeding or bruising or have other signs and symptoms of bleeding such as dizziness; lightheadedness; red or black, tarry stools; coughing up or vomiting fresh or dried blood that looks like coffee grounds; severe headache; and weakness. Do not discontinue the medications without consulting a doctor.
How does the drug interact with Naxdom 500 Tablet:
Co-administration of Ketorolac with Naxdom 500 Tablet can increase the risk of side effects in the gastrointestinal tract such as inflammation, bleeding, ulceration, and rarely, perforation.

How to manage the interaction:
Taking Ketorolac with Naxdom 500 Tablet together is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Naxdom 500 Tablet:
Taking Cidofovir with Naxdom 500 Tablet may increase the risk or severity of kidney problems.

How to manage the interaction:
Taking Cidofovir with Naxdom 500 Tablet is generally avoided as it can result in an interaction. If you experience symptoms such as vomiting, loss of hunger, irregular urination, sudden weight gain or loss, swelling, shortness of breath, muscle cramps, or dizziness. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Naxdom 500 Tablet:
Co-administration of Naxdom 500 Tablet and Bepridil can increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Naxdom 500 Tablet and Bepridil together can cause an interaction, it can be taken if a doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Naxdom 500 Tablet:
Co-administration of Naxdom 500 Tablet and Apixaban can increase the risk of bleeding.

How to manage the interaction:
Taking Naxdom 500 Tablet and Apixaban can lead to an interaction, it can be taken if a doctor advises you to. Consult a doctor if you experience symptoms like unusual bleeding or bruising, tarry stools, coughing up or vomiting blood, severe headache, and weakness. Do not discontinue the medications without consulting a doctor.
How does the drug interact with Naxdom 500 Tablet:
Co-administration of Naxdom 500 Tablet and Celecoxib can increase the risk or severity of stomach inflammation or ulceration.

How to manage the interaction:
Taking Naxdom 500 Tablet and Celecoxib together can result in an interaction, it can be taken if a doctor has advised it. Do not stop using any medications without talking to a doctor.
Severe
How does the drug interact with Naxdom 500 Tablet:
Co-administration of Naxdom 500 Tablet and Rofecoxib can increase the risk or severity of stomach bleeding and rarely lead to serious blood loss.

How to manage the interaction:
There may be a possible interaction between Naxdom 500 Tablet and Rofecoxib, but they can be taken together if a doctor prescribes them. Do not discontinue any medication without a doctor's advice.
Severe
How does the drug interact with Naxdom 500 Tablet:
Co-administration of Naxdom 500 Tablet and Tinzaparin may increase the risk or severity of bleeding problems.

How to manage the interaction:
Taking Naxdom 500 Tablet and Tinzaparin together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult the doctor. Do not discontinue any medication without a doctor's advice.
How does the drug interact with Naxdom 500 Tablet:
Co-administration of Naxdom 500 Tablet and Rivaroxaban may increase the risk or severity of bleeding problems.

How to manage the interaction:
There may be a possible interaction between Naxdom 500 Tablet and Rivaroxaban, but they can be taken together if the doctor prescribes them. However, if you experience unusual bleeding or bruising, or have other signs and symptoms of bleeding such as dizziness; lightheadedness; red or black, stools; coughing up or vomiting fresh or dried blood that looks like coffee grounds; severe headache; and weakness, consult the doctor. Do not discontinue any medication without a doctor's advice.
How does the drug interact with Naxdom 500 Tablet:
Co-administration of Naxdom 500 Tablet and Iodamide may increase the effectiveness of Iodamide.

How to manage the interaction:
There may be a possible interaction between Naxdom 500 Tablet and Iodamide, but they can be taken together if they are prescribed by doctor. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm and weakness consult the doctor. Do not discontinue any medication without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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