Dapalex M 10/500 Tablet contains dapagliflozin and metformin, which are oral medicines used to control diabetes. Mixtard 50 is an insulin and is used when additional blood sugar control is needed. Whether both should be taken together depends on your blood sugar levels, HbA1c, and overall health, and your doctor must make this decision. In some cases, tablets and insulin are prescribed together, but it is not safe to start insulin on your own due to the risk of low blood sugar. Please consult your doctor, who can assess your condition and advise on whether Mixtard 50 is appropriate alongside Dapalex M.