Both your underlying hypothyroidism and your current treatments could be playing a role. Hair changes, like eyebrow thinning, and facial swelling are classic signs of thyroid imbalance. However, supplements containing biotin (in Riotin plus) or high-dose B-vitamins (in Neurofast OD) can sometimes trigger acne. Additionally, skin itching or swelling might suggest a mild sensitivity to one of your supplements or the topical Lashisma. Please share these symptoms with your endocrinologist. They can check your thyroid levels and safely adjust your regimen to help you feel much better.