For temporary relief from severe tooth pain, over-the-counter pain relievers can be highly effective. You can take ibuprofen, which helps reduce inflammation, or acetaminophen (paracetamol). Always follow the package instructions for correct dosages. If safe for you, alternating between these two medications can provide better relief. Holding a cold compress to your cheek or rinsing with warm salt water can also help. Please note that these medications only temporarily mask the pain. Severe tooth pain often indicates an underlying issue like decay or an infection, so it is very important to see a dentist promptly for a proper evaluation and treatment.