Aciloc RD contains two active medicines: omeprazole and domperidone. While omeprazole is generally considered safe during pregnancy, domperidone is typically not recommended, especially during your first trimester at 12 weeks, due to limited safety data. For managing your acid reflux safely, it is best to start with lifestyle adjustments, such as eating smaller, more frequent meals and avoiding lying down right after eating. Safe antacids or single-ingredient medications may also be options. Please consult your obstetrician before taking Aciloc RD so they can recommend the safest and most comfortable treatment plan.