It is generally safe and highly recommended for you to get the COVID-19 vaccine, even with a history of blood clots and while taking Acitrom (acenocoumarol). In fact, protecting yourself against COVID-19 is important because the virus itself can significantly increase your risk of blood clots. Since you are on a blood thinner, there is a small risk of bleeding or bruising at the injection site. To make it safer, please ensure your INR is stable and within your target range before getting the shot. Inform the vaccinator that you take Acitrom so they can use a fine needle and apply firm pressure to the site for at least five minutes afterward.