Yes, Aldactone 100 Tablet (Spironolactone) has anti-androgenic effects. It is primarily a potassium-sparing diuretic used to treat high blood pressure (hypertension) and fluid retention (oedema), but it can also block the action of male hormones (androgens). Because of this, it is sometimes used off-label for conditions such as acne, excess hair growth (hirsutism), and hormonal imbalances. Always consult a doctor before using it for these purposes to ensure it is safe and appropriate for you.