It is quite common for Aldactone (spironolactone) and Obimet SR (metformin) to cause temporary stomach upset and loss of appetite. To help ease this, try taking your medications with meals and stay well-hydrated with small sips of water throughout the day. However, since you are constantly feeling sick and unable to eat, please contact your doctor. They can safely adjust your doses or discuss gentler options to make you more comfortable. Please do not stop taking your medication without consulting them first.
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What should I do if I am constantly feeling sick to my stomach and unable to eat after taking Aldactone and Obimet SR?