Allegra is currently keeping your symptoms under control. While there is no immediate 'permanent cure' for chronic hives, the good news is that they often resolve on their own over time. For a long-term solution, I highly recommend consulting an allergist or dermatologist. They can help identify underlying triggers and discuss advanced, targeted treatments to help you achieve lasting remission.

Given her recent travel and acute calf pain, she needs a prompt medical evaluation to rule out deep vein thrombosis (DVT). The widespread boils and body aches also require urgent assessment to check for any post-operative infection. Please contact her surgeon or visit an emergency room today for an evaluation, which may include a leg ultrasound. For now, she can continue her fexofenadine (Allegra) and nasal spray as prescribed, but please avoid new medications until she is seen.

Since fexofenadine (Allegra) is no longer helping, you might try cetirizine or loratadine, which are effective, daily non-drowsy antihistamines. The skin darkening you are experiencing is likely post-inflammatory hyperpigmentation, a common and temporary response to skin inflammation and scratching that typically fades once the itching stops. To soothe your skin, cool compresses or a mild hydrocortisone cream can help. Consult a healthcare provider to safely adjust your treatment and ensure you find lasting relief.

Fexofenadine (Allegra) is designed to last 24 hours, but if your allergic trigger is strong, symptoms can recur as the drug's peak levels begin to decline. Regarding your blood pressure, hypotension is not a side effect of fexofenadine. Rather, low blood pressure can be a serious complication of a severe allergic reaction, known as anaphylaxis. If you are experiencing low blood pressure, dizziness, or trouble breathing, please seek emergency medical attention immediately.

Since your symptoms return quickly after stopping deflazacort and fexofenadine, it is important to find a safer, long-term solution. Prolonged steroid use can have side effects. Under a specialist's guidance, next steps often involve increasing your daily non-drowsy antihistamine (like fexofenadine) up to four times the standard dose. If this is still ineffective, advanced therapies such as a targeted biologic injection (omalizumab) or other immunomodulating medications can be highly effective. Please consult an allergist or dermatologist to safely transition off the steroid and find a personalized treatment plan.

A severe wet cough with a runny nose is often due to a viral infection and usually improves with rest, fluids, and steam inhalation. If symptoms worsen, fever develops, or breathing becomes difficult, you should consult a doctor for proper evaluation and treatment.