It is completely normal to feel a bit nervous about starting a new medication like sertraline. Please be reassured that this is a very common, safe, and effective option to help support your well-being. In the first couple of weeks, you might experience mild, temporary side effects like slight nausea or minor sleep changes, but these typically fade as your body gently adjusts. It usually takes about four to six weeks to feel the full, positive benefits. Taking it with food can help prevent any stomach upset. You are doing a wonderful job taking proactive steps for your health, and your doctor is always there to support you.