Yes, it is generally safe to take your blood pressure medication, AMLODAC AT (amlodipine/atenolol), alongside your diabetes medications, ISTAMATE (sitagliptin/metformin) and GLUMATE SR (metformin). They work well together to protect your heart and kidneys. However, please be aware that the atenolol in AMLODAC AT can sometimes mask the early warning signs of low blood sugar, such as a fast heart rate. Additionally, since both of your diabetes medications contain metformin, please ensure your doctor is monitoring your total daily dose to keep your kidneys healthy. Please continue taking them as prescribed and monitor your levels regularly.