To lower your diastolic blood pressure, start with lifestyle adjustments: reduce salt intake, exercise regularly, manage stress, and limit alcohol. If lifestyle changes aren't enough, highly effective generic medications are available. Doctors commonly prescribe ACE inhibitors (such as lisinopril), ARBs (such as losartan), Calcium Channel Blockers (such as amlodipine), or thiazide diuretics (such as hydrochlorothiazide). These medications safely relax blood vessels or help remove excess fluid. Managing blood pressure is a very common and highly treatable process. Please consult your healthcare provider to find the safest and most effective plan tailored for you.