Could long-term therapy with aripiprazole (10 mg) and amisulpride (200 mg) cause anal sphincter rigidity or pelvic floor dystonia leading to severe dyschezia and mobility impairment, and what are the recommended diagnostic and management strategies when conservative dietary measures fail? | Apollo Pharmacy

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Could long-term therapy with aripiprazole (10 mg) and amisulpride (200 mg) cause anal sphincter rigidity or pelvic floor dystonia leading to severe dyschezia and mobility impairment, and what are the recommended diagnostic and management strategies when conservative dietary measures fail?

Asked by Female, 40 · 11 days ago

G.santoshini Reddy

M Pharmacy (Pharmaceutics)

11 days ago

Yes, long-term use of medications like aripiprazole and amisulpride can occasionally cause muscle stiffness or spasms, known as dystonia, which can affect the pelvic floor and cause severe difficulty with bowel movements. Please know you are not alone, and this can be managed. I highly recommend discussing this with your prescribing doctor or a neurologist. They can safely evaluate you, perhaps using specialized pelvic tests, and consider gently adjusting your medication or suggesting targeted pelvic floor physical therapy.

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Could long-term therapy with aripiprazole (10 mg) and amisulpride (200 mg) cause anal sphincter rigidity or pelvic floor dystonia leading to severe dyschezia and mobility impairment, and what are the recommended diagnostic and management strategies when conservative dietary measures fail?

Answered 11 days ago

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Could long-term therapy with aripiprazole (10 mg) and amisulpride (200 mg) cause anal sphincter rigidity or pelvic floor dystonia leading to severe dyschezia and mobility impairment, and what are the recommended diagnostic and management strategies when conservative dietary measures fail? | Apollo Pharmacy