It sounds incredibly frustrating, especially since it disrupts your sleep. Since you have not seen improvement after a month of using antihistamines like cetirizine, levocetirizine, and hydroxyzine, alongside your topical creams, it is time for a fresh approach. The next best step is to consult a dermatologist. They can run specific tests to pinpoint the exact cause, which might be nerve-related, severe eczema, or deep dry skin. In the meantime, try using a thick, fragrance-free moisturizing cream immediately after bathing and apply cool compresses to soothe the skin.

If your face has been reacting like this for a long time with dryness, cracking, and weather allergy-type flares, it usually means the skin barrier has become quite sensitive. In conditions like chronic eczema or allergic contact dermatitis, the skin easily loses moisture and reacts again and again to small triggers like dust, temperature change, soaps, or even some creams. That's why antihistamines and steroid creams may calm things down for a while, but the problem comes back once the effect wears off or when the skin gets exposed again. For better long-term control, the main focus should be on daily skin repair rather than only treating flare-ups. Using a very gentle face wash and applying a thick, simple moisturiser regularly can help the skin stay protected and reduce cracking over time. Try to avoid hot water on the face, harsh soaps, scrubbing, or frequently changing products, as all of these can keep the skin irritated. Sun exposure can also make dryness and sensitivity worse, especially around thin areas like under the eyes. Since this has been going on for a year despite treatment, it's worth getting a detailed dermatology review again. Sometimes the exact trigger is missed, and identifying it can make long-term control much easier.

While mild rashes can occasionally happen after a DPT vaccine, the distribution on her face, hands, and legs is also characteristic of insect bites or scabies. If your pediatrician prescribed Nupermy (permethrin) and Atarax (hydroxyzine), they are safe and appropriate for a 15-month-old when used exactly as directed. Permethrin will treat potential scabies, while hydroxyzine will help soothe her itching and keep her comfortable. Please closely follow your doctor's application instructions, and reach out to them if her rash worsens or she develops a fever.

Please do not give Atarax (hydroxyzine) drops to your four-week-old baby without consulting a pediatrician first, as antihistamines can be unsafe for newborns. The red bumps could be common, harmless conditions like baby acne, heat rash, or erythema toxicum, which usually clear up on their own. However, because she is so young, it is very important to have her evaluated by a pediatrician to get an accurate diagnosis and safe treatment plan.

To help manage your hives, try keeping your skin cool with cool compresses and wearing loose, breathable clothing. Avoid hot showers, friction, and potential triggers like stress or alcohol. Since you are already taking cetirizine and hydroxyzine, your doctor might suggest temporarily increasing your daily cetirizine dose (up to four times the standard dose under medical supervision) or adding a short course of oral corticosteroids to quickly calm the inflammation. Please continue using the soothing calamine lotion and consult your doctor before making any medication changes.

Since the rash is worsening despite taking hydroxyzine (Atarax) and deflazacort (DEFZA 6), and applying Labate GM cream, it is very important that you get evaluated by a doctor or visit an urgent care center right away. Your current treatment plan may need to be adjusted. Most importantly, if you develop any swelling of your lips, tongue, or throat, or experience any difficulty breathing or dizziness, please seek emergency medical attention immediately.