Hello. It is very common to feel tired when taking medications like Calchek (amlodipine) and Nitrocontin (nitroglycerin), as they lower your blood pressure. Atchol (atorvastatin) can also occasionally contribute to fatigue. While these side effects can be frustrating, please do not stop taking your prescribed medications suddenly, as they are crucial for your heart health. Your fatigue is a manageable issue. I gently encourage you to consult your doctor, who can check your blood pressure and safely adjust your dosages or timing to help you feel more energetic.