Your elevated IgE and eosinophils point toward an allergic response. A specialist will likely recommend allergy testing to identify triggers, and blood tests to check C1-esterase inhibitor levels to rule out other causes. For treatment, daily non-drowsy antihistamines are often used, and carrying an epinephrine autoinjector is crucial for safety during flares. Regarding vitamins, low vitamin D levels are linked to immune system changes and can sometimes worsen allergic swelling. Correcting any deficiency may help. Please consult an allergist to guide your care.

Since Avil, Tetmosol soap, and the lotion have not provided relief, I highly recommend consulting a dermatologist. The itching could be due to resistant scabies, an allergic reaction, or post-treatment skin sensitivity. In the meantime, try using a gentle, fragrance-free moisturizer to soothe your skin, and avoid hot showers, which can worsen itching. A doctor can safely prescribe targeted treatments, like stronger generic antihistamines or topical creams, to help you find relief and heal.

Since allergy medications did not help, you can try gently soaking your hands and feet in cool water?please avoid ice, as extreme cold can damage the skin. Applying over-the-counter topical lidocaine cream can help numb the burning sensation. Elevating your hands and feet when resting can also help reduce the swelling. Please protect your skin from direct heat, and consider seeing a doctor soon to find the exact cause of these symptoms so you can get the right care.

Your symptoms are very classic for scabies, which is why standard antihistamines and antiseptics haven't provided relief. Please reassure yourself that this is common and highly treatable. The most effective treatments are prescription-strength medications, specifically a topical cream called permethrin, applied from the neck down overnight, or an oral prescription called ivermectin. Because scabies spreads easily, household contacts should be treated at the same time, and bedding should be washed in hot water. Please consult a healthcare provider to get the right prescription so you can finally get some comfortable sleep.

Since pheniramine isn't fully helping, you might find better relief with newer, non-drowsy second-generation antihistamines like cetirizine, loratadine, or fexofenadine. For that stubborn nasal congestion and cough, a daily corticosteroid nasal spray, such as fluticasone, is highly effective. You can also use antihistamine eye drops, like ketotifen, for your itchy eyes. Please consult a healthcare professional to tailor the best treatment plan for you.

Your whole-body rash and facial swelling are worsening despite taking medications and a pheniramine (Avil) injection, this could be a severe allergic reaction. It is very important that you go to the nearest emergency room or urgent care center immediately. You may require stronger, fast-acting treatments like systemic corticosteroids or epinephrine under close medical supervision to safely reverse these symptoms. Please do not wait to see if it improves on its own; a prompt medical evaluation is the safest and most effective way to help you feel better quickly.