I understand how frustrating and uncomfortable this persistent itch must be, especially after 10 days. Since your symptoms are spreading despite using oral pheniramine (Avil) and topical clobetasol (Clobate), it is very important to have this re-evaluated by a healthcare provider. The skin on the neck is delicate, and because clobetasol is a highly potent steroid, continued use without improvement needs professional review. This could be an ongoing contact allergy or even a non-allergic issue, like a fungal infection, which steroids can worsen.

It sounds like you are experiencing an allergic reaction, possibly triggered by something in the hotel food. While Avil (pheniramine) provides temporary relief, the allergen may still be affecting your system, or you might be encountering ongoing triggers. I gently recommend consulting a doctor or allergist who can help identify the exact cause through allergy testing and prescribe a safe, daily non-drowsy antihistamine. Please seek immediate medical care if you ever experience any difficulty breathing, swallowing, or swelling of your lips and throat.

Norfloxacin is typically cleared from your body within 24 hours. However, the allergic immune response it triggered can sometimes persist for several days or even a couple of weeks, which is why you are still seeing hives. Your use of Avil (pheniramine) and levocetirizine is excellent for managing these symptoms, but it can take some time for the skin to fully calm down. Please continue to monitor your symptoms. If you experience any swelling of your lips or face, or have difficulty breathing, please seek medical attention immediately.

Given that the severe itching is on your hands and worsens significantly at night, one strong possibility to consider is scabies, a very common and highly treatable skin condition. Other possibilities include dyshidrotic eczema or contact dermatitis. Because over-the-counter options haven't helped, I highly recommend seeing a healthcare provider for a proper diagnosis. If it is scabies, they can prescribe a generic permethrin cream. If it is eczema, a topical corticosteroid may be recommended.

Your daily symptoms suggest allergic rhinitis or nasal sensitivity triggered by sudden temperature changes from cold water and air conditioning. While Avil (pheniramine) is effective, taking it daily long-term is not recommended, as it can cause drowsiness and lead to tolerance. For daily control, non-drowsy generic antihistamines like cetirizine or fexofenadine are generally safer and more suitable. Please be reassured that this condition is highly manageable. I encourage you to consult a healthcare professional to tailor a safe, daily treatment plan and discuss allergen avoidance strategies.

Avil (pheniramine) can pass into breast milk and may cause drowsiness in your baby, so safer alternatives are generally preferred while breastfeeding. More importantly, because your hives and facial swelling are worsening, it is crucial that you see a doctor immediately. Facial swelling can potentially affect your airway and requires urgent evaluation. A healthcare professional can safely assess your symptoms, provide a more effective, breastfeeding-friendly treatment, and ensure both you and your baby remain safe. Please get evaluated right away.