Itching lasting for three months despite taking medications like CZ3 and Azapure could be due to several reasons, including side effects of the medicines, an underlying skin condition, or an immune-related issue.

🩺 Possible Reasons

• Azapure (azathioprine) suppresses the immune system and can sometimes cause side effects like skin reactions or increased susceptibility to infections, which might contribute to persistent itching.
• CZ3 (likely an antihistamine or related drug) may not fully control itching if the cause is not allergic or if there is another underlying condition.
• Chronic itching can also be caused by dry skin, eczema, liver or kidney issues, or other systemic conditions that need evaluation.

🩺 What You Should Do Next

• Consult a dermatologist or immunologist to evaluate the cause of persistent itching, especially since you are on immunosuppressive therapy.
• Your doctor may recommend blood tests or skin examinations to check for infections, allergic reactions, or other causes.
• Avoid scratching to prevent skin damage and inform your doctor if you notice new symptoms like rash, fever, or swelling.

Seeing a specialist is important to identify the exact cause and adjust your treatment safely. If itching worsens or you develop signs of infection or severe reactions, seek medical attention promptly.To narrow down potential causes, we will need some more information.Please tell me your age and gender. I understand you've been experiencing itching for the past 3 months, even after taking medicines. I'll do my best to help.