For a severe cold, cough, and fever, you can take Acetaminophen (Tylenol) or Ibuprofen to reduce fever and body aches. For a wet cough, an expectorant like Guaifenesin helps clear mucus; for a dry cough, a suppressant like Dextromethorphan is better. An over-the-counter antihistamine or decongestant can relieve nasal congestion. Always read packaging labels carefully to avoid duplicating active ingredients. Please stay well-hydrated, get plenty of rest, and consult a doctor if your fever lasts more than three days, or if you experience difficulty breathing.