Since you have diabetes, skin infections like painful boils (furuncles) can escalate quickly and require professional care. Calamine lotion only soothes itching; it will not cure a bacterial infection. I strongly advise seeing a doctor promptly. You may need a prescription oral antibiotic or an antibiotic ointment (such as mupirocin). In the meantime, apply warm, moist compresses to the area for 10 to 15 minutes, three to four times a day, to help them drain naturally. Please do not squeeze or attempt to pop the boils, as this can spread the infection. Keep monitoring your blood sugar closely.