Ear pain since evening may be due to irritation, infection, or wax, and using Candibiotic just once may not give immediate relief. Avoid putting anything into the ear (including cotton buds), keep the ear dry, and you may take a pain relief tablet if needed, as advised. Do not keep using ear drops repeatedly without proper diagnosis, as the treatment depends on the exact cause. If the pain persists beyond 1-2 days, worsens, or is associated with discharge, fever, or hearing difficulty, you should consult a doctor (ENT) for proper examination and treatment.

Your symptoms suggest irritation or infection of the ear canal, likely worsened by repeated use of cotton buds, which can injure the skin and push infection deeper. Since you now have severe pain and yellow discharge and are not improving with Candibiotic drops, you should stop using cotton buds and avoid putting anything into the ear, keep the ear dry, and seek an ENT doctor's evaluation as soon as possible, as you may need proper cleaning of the ear and specific treatment such as antibiotic or antifungal medication based on the cause. You can take pain relief as advised, but do not self-medicate further, and seek urgent care if pain becomes severe, swelling develops, or hearing is affected.

Recurring ear pain that improves only temporarily with drops like Candibiotic may mean the underlying cause is not fully treated or may not be limited to the ear canal. Your cough and voice changes can sometimes be related, as throat or upper respiratory infections can affect the Eustachian tube (which connects the throat to the ear) and cause ear discomfort. It is best to get examined by an ENT doctor to check both your ear and throat and identify the exact cause. Avoid self-medicating repeatedly with ear drops, keep your ear dry, stay well hydrated, and seek prompt care if symptoms persist, worsen, or are associated with fever, discharge, or hearing changes.