A skin infection that is spreading despite treatment with medicines like fluconazole, LCZ, and Candid Total plus may be a resistant or improperly treated fungal infection. It is important to stop self-medication and consult a dermatologist for proper examination, as you may need the correct antifungal treatment for an adequate duration and possibly lab tests to confirm the diagnosis. In the meantime, keep the area clean and completely dry, wear loose cotton clothing, avoid tight or sweaty garments, and do not share towels or clothes. Avoid using combination creams unless prescribed, and follow the full course of treatment advised to prevent recurrence.