Taking different antibiotics, such as Clindamycin, Cefuroxime, and Spiramycin, without a doctor?s guidance is not recommended, as it may lead to side effects or drug resistance. Antihistamines and hot gargles may help relieve symptoms, but they will not treat the infection itself. Your wife should consult a doctor for a proper diagnosis and, if needed, to select the most appropriate antibiotic.

Since your wife is pregnant, it is important to treat the urinary tract infection promptly to avoid complications. She should see her doctor for a proper urine culture and sensitivity test to identify the bacteria, and then choose a safe antibiotic for pregnancy. Common options include nitrofurantoin or amoxicillin, depending on the bacteria. She should complete the full course as prescribed and stay well hydrated.

Cefuroxime is generally considered safe to use during pregnancy if prescribed by a doctor. It is commonly used to treat bacterial infections and has not been shown to harm the baby. You should only take it under medical supervision and follow the prescribed dose and duration. Always inform your doctor that you are pregnant before starting any antibiotic.