Severe itching around the anal area and genital region can be caused by common problems like a fungal infection, irritation from sweat or tight clothing, poor hygiene, allergic reactions to soaps or sanitary products, or sometimes worms or vaginal infections. To manage this, keep the area clean and dry, wash gently with plain water, avoid harsh or scented products, and wear loose cotton undergarments. An antifungal cream may help if the cause is a fungal infection, but if the itching is intense, persistent, or associated with discharge, pain, or burning, it is important to consult a doctor for proper diagnosis and treatment, which may include antifungal, anti-allergic, or deworming medicines depending on the cause.