Cotaryl Cream contains emollient and keratolytic ingredients that help soften dry, rough, and scaly skin, providing symptomatic relief in conditions like X-linked ichthyosis by improving skin hydration and reducing scaling. However, it does not cure the underlying genetic condition and requires regular, long-term use alongside other moisturisers, as advised by a dermatologist. Skin darkening is not a common major effect with Cotaryl, but irritation or dryness can occur in some people, depending on skin sensitivity and frequency of use. Since X-linked ichthyosis often requires a tailored skincare plan (sometimes combining urea, lactic acid, or ceramide-based creams), it is better to confirm the best option with a dermatologist, especially if you have already experienced side effects with previous treatment.