When taking a combination supplement like L-Arginine, Lycopene, Folic Acid, Vitamin B6, and Vitamin B12, it's important to be aware of potential side effects, although many people tolerate these well.

• L-Arginine can sometimes cause gastrointestinal discomfort, such as bloating, diarrhea, or nausea.
• Lycopene is generally safe but in rare cases might cause digestive upset.
• Folic Acid is usually well tolerated, but very high doses might lead to sleep disturbances or allergic reactions.
• Vitamin B6 in high amounts over long periods can cause nerve-related symptoms like numbness or tingling.
• Vitamin B12 is typically safe with minimal side effects.

If you notice symptoms like persistent stomach pain, unusual skin reactions, numbness, or any other new symptoms after starting this medicine, it's best to consult your doctor promptly. Always take the supplement as directed and inform your doctor about any other medications or health conditions you have to avoid interactions or complications.