Could sequential dosing of paracetamol and a nimesulide/paracetamol combination to treat a high fever cause subsequent severe abdominal pain, cramping, and watery diarrhea?
Yes, taking paracetamol sequentially with a nimesulide and paracetamol combination can cause these symptoms. Nimesulide is a strong anti-inflammatory that can sometimes irritate the stomach lining, leading to abdominal pain, cramping, and diarrhea. Additionally, the high fever itself might be due to a stomach virus causing these digestive issues. Please pause these medications, rest, and focus on sipping fluids to stay hydrated. I highly recommend consulting a healthcare professional to safely evaluate your symptoms, check your liver health after the overlapping doses, and find a gentler way to manage your fever.